TEST BANK
Lehne's Pharmacology for Nursing Care 11th Edition
by
Jacqueline Rosenjack Burchum
,TABLE OF CONTENT
Chapter 01: Orientation to Pharmacology .................................................................................................... 5
Chapter 02: Application of Pharmacology in Nursing Practice .................................................................. 7
Chapter 03: Drug Regulation, Development, Names, and Information Burchum: ................................. 13
Chapter 04: Pharmacokinetics ...................................................................................................................... 16
Chapter 05: Pharmacodynamics .................................................................................................................. 21
Chapter 06: Drug Interactions ...................................................................................................................... 24
Chapter 07: Adverse Drug Reactions and Medication Errors .................................................................. 29
Chapter 08: Individual Variation To Drug Responses ............................................................................... 35
Chapter 09: Genetic and Genomic Considerations ..................................................................................... 39
Chapter 10: Introduction to Immunomodulators ....................................................................................... 42
Chapter 11: Drug Therapy During Pregnancy and Breast-Feeding Burchum: ...................................... 45
Chapter 12: Drug Therapy in Pediatric Patients ........................................................................................ 49
Chapter 13: Drug Therapy in Older Adults ................................................................................................ 52
Chapter 14: Basic Principles of Neuropharmacology ................................................................................. 57
Chapter 15: Physiology of the Peripheral Nervous System........................................................................ 60
Chapter 16: Muscarinic Agonists ................................................................................................................. 63
Chapter 17: Muscarinic Antagonists ............................................................................................................ 66
Chapter 18: Cholinesterase Inhibitors and Their Use in Myasthenia Gravis Burchum ......................... 69
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission Burchum: ...................................... 72
Chapter 20: Adrenergic Agonists ................................................................................................................. 76
Chapter 21: Adrenergic Antagonists ............................................................................................................ 80
Chapter 22: Indirect-Acting Antiadrenergic Agents .................................................................................. 86
Chapter 23: Introduction to Central Nervous System Pharmacology Burchum: ................................... 90
Chapter 24: Drugs for Parkinson Disease ................................................................................................... 93
Chapter 25: Drugs for Alzheimer Disease ................................................................................................... 98
Chapter 26: Drugs for Multiple Sclerosis .................................................................................................. 102
Chapter 27: Drugs for Seizure Disorders .................................................................................................. 107
Chapter 28: Drugs for Muscle Spasm and Spasticity ............................................................................... 114
Chapter 29: Local Anesthetics .................................................................................................................... 117
Chapter 30: General Anesthetics ................................................................................................................ 121
Chapter 31: Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ..... 127
Chapter 32: Pain Management in Patients with Cancer .......................................................................... 132
Chapter 33: Drugs for Headache ................................................................................................................ 139
Chapter 34: Antipsychotic Agents and Their Use in Schizophrenia Burchum: .................................... 143
Chapter 35: Antidepressants ....................................................................................................................... 149
Chapter 36: Drugs for Bipolar Disorder .................................................................................................... 155
Chapter 37: Sedative-Hypnotic Drugs ....................................................................................................... 160
Chapter 38: Management of Anxiety Disorders........................................................................................ 165
Chapter 39: Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder ....... 169
2
,Chapter 40: Substance Use Disorders I: Basic Considerations ............................................................... 173
Chapter 41: Substance Use Disorders II: Alcohol..................................................................................... 177
Chapter 42: Substance Use Disorders III: Nicotine .................................................................................. 183
Chapter 43: Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine 187
Chapter 44: Diuretics ................................................................................................................................... 193
Chapter 45: Agents Affecting the Volume and Ion Content of Body Fluids Burchum: ....................... 197
Chapter 46: Review of Hemodynamics ...................................................................................................... 202
Chapter 47: Drugs Acting on the Renin-Angiotensin-Aldosterone System Burchum: ........................ 204
Chapter 48: Calcium Channel Blockers..................................................................................................... 209
Chapter 49: Vasodilators ............................................................................................................................. 211
Chapter 50: Drugs for Hypertension .......................................................................................................... 215
Chapter 51: Drugs for Heart Failure ......................................................................................................... 222
Chapter 52: Antidysrhythmic Drugs .......................................................................................................... 229
Chapter 53: Drugs That Help Normalize Cholesterol and Triglyceride Levels Burchum: .................. 236
Chapter 54: Drugs for Angina Pectoris ..................................................................................................... 242
Chapter 55: Anticoagulant, Antiplatelet, and Thrombolytic Drugs Burchumr .................................... 248
Chapter 56: Management of ST-Elevation Myocardial Infarction Burchum: ...................................... 255
Chapter 57: Drugs for Hemophilia ............................................................................................................. 259
Chapter 58: Drugs for Deficiency Anemias ............................................................................................... 263
Chapter 59: Hematopoietic Agents ............................................................................................................. 269
Chapter 60: Drugs for Diabetes Mellitus ................................................................................................... 273
Chapter 61: Drugs for Thyroid Disorders ................................................................................................. 279
Chapter 62: Drugs Related to Hypothalamic and Pituitary Function Burchum: ................................. 284
Chapter 63: Drugs for Disorders of the Adrenal Cortex .......................................................................... 288
Chapter 64: Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications ..... 292
Chapter 65: Birth Control ........................................................................................................................... 296
Chapter 66: Drug Therapy for Infertility .................................................................................................. 301
Chapter 67: Drugs That Affect Uterine Function ..................................................................................... 305
Chapter 68: Androgens ................................................................................................................................ 310
Chapter 69: Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia Burchum: r .............. 314
Chapter 70: Review of the Immune System............................................................................................... 318
Chapter 71: Childhood Immunization ....................................................................................................... 322
Chapter 72: Immunosuppressants .............................................................................................................. 327
Chapter 73: Antihistamines ........................................................................................................................ 331
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-inflammatory Drugs and Acetaminophen
........................................................................................................................................................................ 336
Chapter 75: Glucocorticoids in Nonendocrine Disorders ........................................................................ 341
Chapter 76: Drug Therapy for Rheumatoid Arthritis ............................................................................. 347
Chapter 77: Drug Therapy for Gout .......................................................................................................... 350
Chapter 78: Drugs Affecting Calcium Levels and Bone Mineralization Burchum ............................... 353
3
, Chapter 79: Drugs for Asthma and Chronic Obstructive Pulmonary Disease
Burchum…………………………………………………………………………………………………..:359
Chapter 80: Drugs for Allergic Rhinitis, Cough, and Colds .................................................................... 366
Chapter 81: Drugs for Peptic Ulcer Disease .............................................................................................. 371
Chapter 82: Laxatives .................................................................................................................................. 376
Chapter 83: Other Gastrointestinal Drugs ................................................................................................ 381
Chapter 84: Vitamins ................................................................................................................................... 388
Chapter 85: Drugs for Weight Loss ........................................................................................................... 394
Chapter 86: Complementary and Alternative Therapy ........................................................................... 399
Chapter 87: Basic Principles of Antimicrobial Therapy .......................................................................... 402
Chapter 88: Drugs That Weaken the Bacterial Cell Wall I: Penicillins Burchumg .............................. 407
Chapter 89: Drugs That Weaken the Bacterial Cell Wall II: Other Drugs Burchum: ......................... 412
Chapter 90: Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides, and Others .. 416
Chapter 91: Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis Burchum: ...................... 424
Chapter 92: Sulfonamides and Trimethoprim .......................................................................................... 430
Chapter 93: Drug Therapy for Urinary Tract Infections ........................................................................ 434
Chapter 94: Antimycobacterial Agents ...................................................................................................... 440
Chapter 95: Miscellaneous Antibacterial Drugs ....................................................................................... 447
Chapter 96: Antifungal Agents ................................................................................................................... 451
Chapter 97: Antiviral Agents I: Drugs for Non-HIV Viral Infections Burchum: ................................. 458
Chapter 98: Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections ...... 463
Chapter 99: Drug Therapy for Sexually Transmitted Diseases ............................................................... 468
Chapter 100: Antiseptics and Disinfectants ............................................................................................... 472
Chapter 101: Anthelmintics ........................................................................................................................ 476
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents ..................................................................... 479
Chapter 103: Antiprotozoal Drugs II: Miscellaneous Agents .................................................................. 483
Chapter 104: Ectoparasiticides ................................................................................................................... 485
Chapter 105: Basic Principles of Cancer Chemotherapy ......................................................................... 489
Chapter 106: Anticancer Drugs I: Cytotoxic Agents ................................................................................ 495
Chapter 107: Anticancer Drugs II: Noncytotoxic Agents ........................................................................ 500
Chapter 108: Drugs for the Eye .................................................................................................................. 504
Chapter 109: Drugs for the Skin................................................................................................................. 509
Chapter 110: Drugs for the Ear .................................................................................................................. 516
Chapter 111: Management of Poisoning .................................................................................................... 521
Chapter 112: Potential Weapons of Biologic, Radiologic, and Chemical Terrorism Burchum: .......... 525
4
Lehne's Pharmacology for Nursing Care 11th Edition
by
Jacqueline Rosenjack Burchum
,TABLE OF CONTENT
Chapter 01: Orientation to Pharmacology .................................................................................................... 5
Chapter 02: Application of Pharmacology in Nursing Practice .................................................................. 7
Chapter 03: Drug Regulation, Development, Names, and Information Burchum: ................................. 13
Chapter 04: Pharmacokinetics ...................................................................................................................... 16
Chapter 05: Pharmacodynamics .................................................................................................................. 21
Chapter 06: Drug Interactions ...................................................................................................................... 24
Chapter 07: Adverse Drug Reactions and Medication Errors .................................................................. 29
Chapter 08: Individual Variation To Drug Responses ............................................................................... 35
Chapter 09: Genetic and Genomic Considerations ..................................................................................... 39
Chapter 10: Introduction to Immunomodulators ....................................................................................... 42
Chapter 11: Drug Therapy During Pregnancy and Breast-Feeding Burchum: ...................................... 45
Chapter 12: Drug Therapy in Pediatric Patients ........................................................................................ 49
Chapter 13: Drug Therapy in Older Adults ................................................................................................ 52
Chapter 14: Basic Principles of Neuropharmacology ................................................................................. 57
Chapter 15: Physiology of the Peripheral Nervous System........................................................................ 60
Chapter 16: Muscarinic Agonists ................................................................................................................. 63
Chapter 17: Muscarinic Antagonists ............................................................................................................ 66
Chapter 18: Cholinesterase Inhibitors and Their Use in Myasthenia Gravis Burchum ......................... 69
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission Burchum: ...................................... 72
Chapter 20: Adrenergic Agonists ................................................................................................................. 76
Chapter 21: Adrenergic Antagonists ............................................................................................................ 80
Chapter 22: Indirect-Acting Antiadrenergic Agents .................................................................................. 86
Chapter 23: Introduction to Central Nervous System Pharmacology Burchum: ................................... 90
Chapter 24: Drugs for Parkinson Disease ................................................................................................... 93
Chapter 25: Drugs for Alzheimer Disease ................................................................................................... 98
Chapter 26: Drugs for Multiple Sclerosis .................................................................................................. 102
Chapter 27: Drugs for Seizure Disorders .................................................................................................. 107
Chapter 28: Drugs for Muscle Spasm and Spasticity ............................................................................... 114
Chapter 29: Local Anesthetics .................................................................................................................... 117
Chapter 30: General Anesthetics ................................................................................................................ 121
Chapter 31: Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ..... 127
Chapter 32: Pain Management in Patients with Cancer .......................................................................... 132
Chapter 33: Drugs for Headache ................................................................................................................ 139
Chapter 34: Antipsychotic Agents and Their Use in Schizophrenia Burchum: .................................... 143
Chapter 35: Antidepressants ....................................................................................................................... 149
Chapter 36: Drugs for Bipolar Disorder .................................................................................................... 155
Chapter 37: Sedative-Hypnotic Drugs ....................................................................................................... 160
Chapter 38: Management of Anxiety Disorders........................................................................................ 165
Chapter 39: Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder ....... 169
2
,Chapter 40: Substance Use Disorders I: Basic Considerations ............................................................... 173
Chapter 41: Substance Use Disorders II: Alcohol..................................................................................... 177
Chapter 42: Substance Use Disorders III: Nicotine .................................................................................. 183
Chapter 43: Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine 187
Chapter 44: Diuretics ................................................................................................................................... 193
Chapter 45: Agents Affecting the Volume and Ion Content of Body Fluids Burchum: ....................... 197
Chapter 46: Review of Hemodynamics ...................................................................................................... 202
Chapter 47: Drugs Acting on the Renin-Angiotensin-Aldosterone System Burchum: ........................ 204
Chapter 48: Calcium Channel Blockers..................................................................................................... 209
Chapter 49: Vasodilators ............................................................................................................................. 211
Chapter 50: Drugs for Hypertension .......................................................................................................... 215
Chapter 51: Drugs for Heart Failure ......................................................................................................... 222
Chapter 52: Antidysrhythmic Drugs .......................................................................................................... 229
Chapter 53: Drugs That Help Normalize Cholesterol and Triglyceride Levels Burchum: .................. 236
Chapter 54: Drugs for Angina Pectoris ..................................................................................................... 242
Chapter 55: Anticoagulant, Antiplatelet, and Thrombolytic Drugs Burchumr .................................... 248
Chapter 56: Management of ST-Elevation Myocardial Infarction Burchum: ...................................... 255
Chapter 57: Drugs for Hemophilia ............................................................................................................. 259
Chapter 58: Drugs for Deficiency Anemias ............................................................................................... 263
Chapter 59: Hematopoietic Agents ............................................................................................................. 269
Chapter 60: Drugs for Diabetes Mellitus ................................................................................................... 273
Chapter 61: Drugs for Thyroid Disorders ................................................................................................. 279
Chapter 62: Drugs Related to Hypothalamic and Pituitary Function Burchum: ................................. 284
Chapter 63: Drugs for Disorders of the Adrenal Cortex .......................................................................... 288
Chapter 64: Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications ..... 292
Chapter 65: Birth Control ........................................................................................................................... 296
Chapter 66: Drug Therapy for Infertility .................................................................................................. 301
Chapter 67: Drugs That Affect Uterine Function ..................................................................................... 305
Chapter 68: Androgens ................................................................................................................................ 310
Chapter 69: Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia Burchum: r .............. 314
Chapter 70: Review of the Immune System............................................................................................... 318
Chapter 71: Childhood Immunization ....................................................................................................... 322
Chapter 72: Immunosuppressants .............................................................................................................. 327
Chapter 73: Antihistamines ........................................................................................................................ 331
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-inflammatory Drugs and Acetaminophen
........................................................................................................................................................................ 336
Chapter 75: Glucocorticoids in Nonendocrine Disorders ........................................................................ 341
Chapter 76: Drug Therapy for Rheumatoid Arthritis ............................................................................. 347
Chapter 77: Drug Therapy for Gout .......................................................................................................... 350
Chapter 78: Drugs Affecting Calcium Levels and Bone Mineralization Burchum ............................... 353
3
, Chapter 79: Drugs for Asthma and Chronic Obstructive Pulmonary Disease
Burchum…………………………………………………………………………………………………..:359
Chapter 80: Drugs for Allergic Rhinitis, Cough, and Colds .................................................................... 366
Chapter 81: Drugs for Peptic Ulcer Disease .............................................................................................. 371
Chapter 82: Laxatives .................................................................................................................................. 376
Chapter 83: Other Gastrointestinal Drugs ................................................................................................ 381
Chapter 84: Vitamins ................................................................................................................................... 388
Chapter 85: Drugs for Weight Loss ........................................................................................................... 394
Chapter 86: Complementary and Alternative Therapy ........................................................................... 399
Chapter 87: Basic Principles of Antimicrobial Therapy .......................................................................... 402
Chapter 88: Drugs That Weaken the Bacterial Cell Wall I: Penicillins Burchumg .............................. 407
Chapter 89: Drugs That Weaken the Bacterial Cell Wall II: Other Drugs Burchum: ......................... 412
Chapter 90: Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides, and Others .. 416
Chapter 91: Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis Burchum: ...................... 424
Chapter 92: Sulfonamides and Trimethoprim .......................................................................................... 430
Chapter 93: Drug Therapy for Urinary Tract Infections ........................................................................ 434
Chapter 94: Antimycobacterial Agents ...................................................................................................... 440
Chapter 95: Miscellaneous Antibacterial Drugs ....................................................................................... 447
Chapter 96: Antifungal Agents ................................................................................................................... 451
Chapter 97: Antiviral Agents I: Drugs for Non-HIV Viral Infections Burchum: ................................. 458
Chapter 98: Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections ...... 463
Chapter 99: Drug Therapy for Sexually Transmitted Diseases ............................................................... 468
Chapter 100: Antiseptics and Disinfectants ............................................................................................... 472
Chapter 101: Anthelmintics ........................................................................................................................ 476
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents ..................................................................... 479
Chapter 103: Antiprotozoal Drugs II: Miscellaneous Agents .................................................................. 483
Chapter 104: Ectoparasiticides ................................................................................................................... 485
Chapter 105: Basic Principles of Cancer Chemotherapy ......................................................................... 489
Chapter 106: Anticancer Drugs I: Cytotoxic Agents ................................................................................ 495
Chapter 107: Anticancer Drugs II: Noncytotoxic Agents ........................................................................ 500
Chapter 108: Drugs for the Eye .................................................................................................................. 504
Chapter 109: Drugs for the Skin................................................................................................................. 509
Chapter 110: Drugs for the Ear .................................................................................................................. 516
Chapter 111: Management of Poisoning .................................................................................................... 521
Chapter 112: Potential Weapons of Biologic, Radiologic, and Chemical Terrorism Burchum: .......... 525
4
