Final Exam: NR 568 (NR568) |Latest 2023/ 2024| Advanced Pharmacology for the Adult-Gerontology Primary Care Nurse Practitioner| Guide with Verified Answers- Chamberlain

Final Exam: NR 568 (NR568) |Latest 2023/ 2024| Advanced Pharmacology for the Adult-Gerontology Primary Care Nurse Practitioner| Guide with Verified Answers- Chamberlain Q: How to treat TCA toxicity? Answer: NaHCO3 Q: Examples of MAOIs Answer: phenelzine (Nardil) Isocarboxazid (Marplan) Tranylcypromine (Parnate) Selegiline (Emsam)-transdermal MAOI Q: Adverse effect of MAOIs Answer: hypertensive crisis Q: Which medications increase risk of HTN with MAOIs? Answer: Sympathometics TCA SSRI/SNRI Q: Baseline assessment before starting MAOIs? (*think: adverse reactions) Answer: Baseline BP Q: Examples of atypical antidepressants Answer: bupropion, mirtazapine Q: Adverse reactions of Bupropion Answer: Seizures Psychotic effects Q: Signs of Extrapyramidal effects Answer: 1. Acute dystonia (abn. movements) 2. Parkinsonism 3. Akathisia (restlessness) 4. Tardive dyskinesia (wormlike tongue movement) *Late effect *2nd generation antipsychotics are less likely to cause EPS Q: 1st generation antipsychotics Answer: Haloperidol Chlorpromazine Q: 2nd generation antipsychotics Answer: clozapine, risperidone, olanzapine Q: side effect of haldol Answer: QT prolongation, EPS Q: Patients to avoid giving haldol to and why Answer: Pts with Parkinson's, depression, dementia Death can occur with dementia related psychosis Q: Adverse reaction with 2nd generation antipsychotics (clozapine) Answer: Agranulocytosis (black box) New onset diabetes HLD Seizures Myocarditis Q: Monitoring with 2n generation antipsychotics (*think side effects) Answer: - WBC & neutrophils must be WNL prior to starting and monitored throughout beginning of treatment - Glucose levels - Lipids - Electrolytes - Weight - EKG Q: Would should antidepressants not be given alone with Bipolar Disorder? Answer: Can cause mania or hypomania Q: Why TCAs be avoided with Bipolar Disorder? Answer: Can worsen mania Q: Why should caution be taken when combining lithium with diuretics? Answer: Can cause dehydration and lead to lithium retention Q: Black box warning: Lithium Answer: Lithium toxicity Hepatotoxicity Pancreatitis Teratogenic