Handling Hazardous drugs| Questions and answers with 100% correct answers | Verified

Define Hazardous Drugs - Prescription drugs directly toxic or have potential for toxicity to the patient using the drug. A drug labeled hazardous posses toxicity risk to healthcare workers who come in contact with drug. What are the 3 hazardous drug categories? - antineoplastics non-antineoplastics (hormones and transplant drugs) reproductive risk NIOSH - National Institute for Occupational Safety and Health. Determines which drugs a re hazardous and produces a list. US pharmacopoeia (USP) - sets standards on how to work safely with hazardous drugs. Chapter 800, adds to but does not replace 795 or 797 ASHP - provides detailed guidance for hospital pharmacist on implementing USP standards What are the two options for risk assessment? - 1. Follow all recommendations in USP chapter 800 2. Conduct risk assessment to determine appropriate procedures for managing drugs that will be less stringent than USP 800 requirements. Hazardous drug categories - Teratogeinc (all cetogry X or D drugs, paroxetine, mtx, misoprostol, mifepristine, ribavarin) Carcinogenic ( chemotherapy) genotoxichormones (contracetpives, estradiol, testosterone) Transplant drugs (mycophenolate, tacrolimus, cyclosproine, everolimus, sirolimus) Others: colchicine, fluconazole, spironolactone, risperidone, raloxefiene, rasagliine, ziprasidone Engineering controls - Primary: ventilated hood Secondary: the room where hood is located Supplemental: additional tools for protection Standards that apply to sterile and non-sterile HD compounding - each type should be compounded in separate room (sterile HD, non-sterile HD, sterile non HD, non sterile non HD,etc) with the exception of sterile and non-sterile HDs can be made in same room if has ISO 7 air during non sterile compounding and placed at least 1 meter apart