NUR 2474 Pharmacology for Professional Nursing Quiz 1: Quiz 1 Pharm: Guaranteed A+ Score: Latest Updated: Rasmussen

Properties of the ideal drug Ch 1 p. 2 Effective*** Safe* Selective* Reversible action Predictable Ease of administration - fewer administration errors Freedom from drug interactions Low cost Chemical stability Possession of a simple generic name No adverse effects *most important What items are desired when selecting a drug? Ch 1 p. 3 -maximum benefit, minimum harm What are physiological considerations that should be considered in medication selection? Ch 1 p. 4 -Age Gender Weight Race Past reactions to medications Why is ease of administration important? Ch 1 p. 2 Convenience 1. it can increase adherence among patients (more compliant) 2. It can decrease risk (skin integrity/infection with injections) determine how much of an administered dose gets to its sites of action movement of a drug through a body what the body does to the drug 4 processes: - Absorption - Distribution - Metabolism (biotransformation) - Excretion (elimination) Ch 1 p. 3 >Pharmacokinetics The molecular interactions of a drug with specific biological receptors on or in the body's cells, which lead to a desired therapeutic response what the drug does to the body; mechanism of action Ch 1 p. 3 >Pharmacodynamics a drug that elicits only the response for which it is given "no side effects (ideally)" Ch 1 p.2 Selectivity *there is no such thing as a wholly selective drug because all drugs cause side effects the ability to know how the body will react to an administered drug Ch 1 p.2 Predictability the time required for the amount of drug in the body to decrease by 50% Ch 4 p.40 Half life why do we care? The half-life of a drug determines the dosing interval (i.e., how much time separates each dose). combination of metabolism and excretion