Maryville NURS 615 Pharm 3 exam with all the correct answers (100% Verified 2020/2021 exam)

How do antigout medications work? Correct Answer- by inhibiting the infiltration and phagocytosis of leukocytes, thus decreasing the breakdown of uric acid to urate crystals. Deposition of urate crystals causes Correct Answer- pain and inflammation What is Colchicine Correct Answer- anti-gout medication how does Colchicine work? Correct Answer- Works by inhibiting inflammation, reducing pain and swelling common side effects of Colchicine Correct Answer- GI problems (diarrhea) use with caution in elderly Also can cause blood dyscrasias & abdominal pain patient education with Colchicine Correct Answer- Can be given with food & milk to decrease GI issues Avoid beer, ale, & wine: may cause gout attack Increase fluid intake: increases excretion of uric acid Avoid smoked meats & high-protein diets Low dose of Colchicine Correct Answer- Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8 milligrams total High dose of Colchicine Correct Answer- high dose colchicine is 1.2mg followed by 0.6mg every four to six hours; or 4.8mg total. Difference between high dose and low dose Colchicine Correct Answer- The difference between the two is low dose is as effective as high dose with a lower side effect profile. Lab values to monitor with Colchicine Correct Answer- Check renal function test, BUN, Creatine