WGU 785 Final Exam Latest 2021 With Complete Solution

WGU 785 Final Exam Latest 2021 With Complete Solution 1. Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome for their kids?: His daughters would be carriers. This is x-link recessive. 2. Autosomal: Dominant:: Autosomal: males and females equally affected. Dominant: non-carrier parents 3. polymerase chain reaction (PCR): The process of copying DNA in the lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA primers. 4. 3 Steps of PCR: 1. Denaturation: DNA is heated to 95C to separate it. 2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and add DNA polymerase. 3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building a new DNA strand. 5. Base Excision Repair (BER): How you repair a mutation. BER is used to repair damage to a base caused by harmful molecules. You remove the base that is damaged and replace it. *BER removes a single nucleotide* DNA glycolsylase - sees damaged DNA and removes it. DNA polymerase-puts the right one back in while DNA ligase seals it. 6. Mismatch repair (MMR) occurs during:: replication. DNA polymerase proof- reads but sometimes a mismatch pair gets through. MMR removes a large section of the nucleotides from the new DNA and DNA polymerase tries again. (Ex: C-T instead of C-A) 7. Mismatch Repair corrects what kind of DNA damage?: When a base is mis- matched due to errors in replication. Such as G-T instead of G-C. DNA polymerase comes by and fixes it. 8. What happens when