Nursing 54A - Hepatic Pathophysiology. Complete Study Guide.

Hepatic Pathophysiology  Hepatic includes the liver, gallbladder and pancreas  2 things to look at: 1. Function of the liver 2. Structure or the liver  Both have implications in the manifestations of disease  Some DOs impact more the structure of the liver and that will present in a certain, vice versa Physiology and Function of Bile Flow  Bile flow- starts intrahepatic then goes extrahepatic  Bile is composed of primarily water, but cholesterol, bile acids (primary and secondary), pigments are present  Bile produced by hepatocytes in liver; they have intrahepatic ducts, ends up being stored in gallbladder o Primary bile acids: choli, chenodeoxycholic acid o Secondary bile acids: deoxycholic acid, ursodeoxycholic acid, lithocholic acid o Composed primarily of H2O, electrolytes, organic solute; low protein content o Additional components include pigment cholesterol phospholipids Physiology and Function of Bile Flow Gallbladder  Purpose of the gallbladder (GB) is not just to store the bile for use when we need extra bile for fatty foods (emulsification of fats?),