University of Alberta
Department of Biochemistry
NAME:
CLEARLY WRITE YOUR I.D. # ON EACH PAGE INSIDE
University of Alberta
Department of Biochemistry
BIOCH 330
Midterm Exam
Dr. J. Parrish
Time Limit: 80 minutes February 16, 2023
INSTRUCTIONS
• Enter your NAME on this cover page and your I.D.# on each page inside.
• Check that you have 10 pages.
• Ensure all multiple choice questions are completed on the scantron sheet.
• Ensure your scantron sheet has your NAME and I.D.#
• Short-answer questions should be answered in the spaces provided.
• This exam contains 42 marks worth 40% of your final grade.
Page 1 of 10
, Part A: Multiple Choice, please complete on the scantron sheet.
1. Which of the statements below is true for the four common deoxynucleotides?
A. The substituent at position 2 of pyrimidines is a hydrogen bond acceptor.
B. Nitrogen 7 in purines is always a hydrogen bond donor.
C. The anti conformation for thymine will place a carbonyl group over the deoxyribose
ring.
D. Purines are attached to the sugar through N1.
E. None of the above statements are true.
2. The sugar structure shown above…
A. … is found in RNA and not DNA.
B. … is in the conformation you would expect to find in B DNA
C. … is in a conformation found in Z-DNA.
D. … will only be found with anti glycosidic bond conformations.
E. Both choices C and D can complete this sentence.
3. Which of the statements below describes a role for E. coli DNA Pol III?
A. Lagging strand synthesis.
B. Base excision repair.
C. Mismatch repair.
D. Both A and C.
E. All of these are roles for DNA Pol III.
4. Which of the following statements is FALSE regarding DnaA?
A. DnaA is a sequence that is part of oriC in E. coli.
B. DnaA is an important component in DNA replication initiation.
C. DnaA affects the writhe in oriC in E. coli.
D. Both A and B are false.
E. Both B and C are false.
Department of Biochemistry
NAME:
CLEARLY WRITE YOUR I.D. # ON EACH PAGE INSIDE
University of Alberta
Department of Biochemistry
BIOCH 330
Midterm Exam
Dr. J. Parrish
Time Limit: 80 minutes February 16, 2023
INSTRUCTIONS
• Enter your NAME on this cover page and your I.D.# on each page inside.
• Check that you have 10 pages.
• Ensure all multiple choice questions are completed on the scantron sheet.
• Ensure your scantron sheet has your NAME and I.D.#
• Short-answer questions should be answered in the spaces provided.
• This exam contains 42 marks worth 40% of your final grade.
Page 1 of 10
, Part A: Multiple Choice, please complete on the scantron sheet.
1. Which of the statements below is true for the four common deoxynucleotides?
A. The substituent at position 2 of pyrimidines is a hydrogen bond acceptor.
B. Nitrogen 7 in purines is always a hydrogen bond donor.
C. The anti conformation for thymine will place a carbonyl group over the deoxyribose
ring.
D. Purines are attached to the sugar through N1.
E. None of the above statements are true.
2. The sugar structure shown above…
A. … is found in RNA and not DNA.
B. … is in the conformation you would expect to find in B DNA
C. … is in a conformation found in Z-DNA.
D. … will only be found with anti glycosidic bond conformations.
E. Both choices C and D can complete this sentence.
3. Which of the statements below describes a role for E. coli DNA Pol III?
A. Lagging strand synthesis.
B. Base excision repair.
C. Mismatch repair.
D. Both A and C.
E. All of these are roles for DNA Pol III.
4. Which of the following statements is FALSE regarding DnaA?
A. DnaA is a sequence that is part of oriC in E. coli.
B. DnaA is an important component in DNA replication initiation.
C. DnaA affects the writhe in oriC in E. coli.
D. Both A and B are false.
E. Both B and C are false.
