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CSP Exam Test | 2026 | 200+ Verified Q&A on Specialty Medications, Oncology, Hepatitis, HIV, and MS Treatment

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This expert-verified study guide provides over 200 exam-style questions and answers specifically designed for the Certified Specialty Pharmacist (CSP) exam, updated for the 2026 certification cycle. Structured in a high-yield flashcard format, the content covers a broad range of specialty pharmaceutical domains, making it an essential revision tool for pharmacy professionals aiming for certification. Key clinical areas covered include: Specialty drug classes and clinical indications: Immunomodulators, Jak inhibitors (e.g., Xeljanz), biologics for psoriasis and arthritis (e.g., Humira, Stelara, Dupixent), MS treatments (e.g., Tecfidera, Copaxone, Gilenya) Oncology medications and protocols: Oral chemotherapy cycles, food-drug interactions (e.g., Xeloda, Zytiga), hepatic impairment dosing, black box warnings (e.g., Iclusig), REMS programs (e.g., Revlimid, Thalomid) HIV and hepatitis therapeutics: CD4-based treatment initiation, PrEP regimens (e.g., Truvada), contraindications, drug interactions (e.g., Vosevi + omeprazole), and HBV reactivation risks Adherence metrics and specialty operations: Proportion of Days Covered (PDC) vs MPR, refill logic, billing hierarchies (Medicare/Medicaid), limited distribution drugs, and cold-chain logistics Clinical scenarios: Case-based questions on statin selection, MS medication and pregnancy, vaccine contraindications in immunocompromised patients, and specialty pharmacy handling Each answer is clearly labeled and immediately follows the question, enhancing usability for self-testing, rapid revision, and exam simulation. Best suited for: Pharmacists preparing for the CSP certification Clinical pharmacists and pharmacy residents in ambulatory, oncology, infectious disease, or MS-focused roles Specialty pharmacy technicians and pharmacy managers seeking deeper knowledge in specialty drug protocols Pharmacy educators and trainers compiling test prep or case-based learning content The document’s practical Q&A layout and up-to-date therapeutic coverage make it a powerful asset for both independent study and structured CSP prep courses. Keywords: CSP exam, 2026 certification, specialty pharmacy, oncology medications, HIV treatment, hepatitis C, MS drugs, REMS program, immunotherapy, Jak inhibitors, CD4 count, PrEP, oral chemotherapy, biologics, specialty medication storage, PDC, MPR, Medicare billing, cold chain logistics, pharmacy operations, Zytiga, Stelara, Xeljanz, Tecfidera, Gilenya, Epclusa, Truvada, omeprazole interaction, medication counseling, vaccine safety, drug reconstitution, formulary management

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CSP - Certified Safety Professional
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Institution
CSP - Certified Safety Professional
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CSP - Certified Safety Professional

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Uploaded on
January 30, 2026
Number of pages
30
Written in
2025/2026
Type
Exam (elaborations)
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Questions & answers

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CSP Exam Test 2026 Exam
Questions and Answers | A+
Score Assured



PDC calculation - 🧠ANSWER ✔✔PDC = (# of unique days with supply /

number of days in a period) x 100

Which medication is a Jak inhibitor?

a. Humira (adalimumab)

b. Orencia (abatacept)

c. Actemra (toclizumab)


d. Xeljanz (tofacitinib) - 🧠ANSWER ✔✔d. Xeljanz (tofacitinib)

,Which medication can elevate cholesterol?

a. Actemra (toclizumab)

b. Enbrel (etanercept)

c. Simponi (golimumab)


d. Kineret (anakinra) - 🧠ANSWER ✔✔a. Actemra (toclizumab)


Which shingles vaccine is safe to administer with TNF inhibitors?

a. Adacel

b. Zostavax

c. Shingrix


d. Varivax - 🧠ANSWER ✔✔c. Shingrix


Most biologics increase the risk of infections, which of the following also

increases the risk of

neutropenia?

a. Rituxin (rituximab)

b. Taltz (ixekizumab)

c. Remicade (infliximab)

, d. Cimzia (certolizumab pegol) - 🧠ANSWER ✔✔b. Taltz (ixekizumab)


Which psoriasis medication does not require screening for tuberculosis?

a. Stelara (ustekinumab)

b. Otezla (apremilast)

c. Cocentyx (seculinumab)


d. Humira (adalimumab) - 🧠ANSWER ✔✔b. Otezla (apremilast)


What is the standard starting dose for Taltz (ixekizumab) when used to

treat psoriatic arthritis?

a. 160mg subcutaneously once, followed by 80mg subcutaneously at

weeks 2, 4, 6, 8, 10

and 12; then 80mg subcutaneously every 4 weeks

b. 160mg subcutaneously once, followed by 80mg subcutaneously every 4

weeks

c. 160mg subcutaneously once, followed by 80mg subcutaneously every

week for 4 weeks,

then 80mg every 4 weeks




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