NR 565 - advanced pharmacology midterm – Chamberlain ALL
QUESTIONS AND 100% CORRECT ANSWERS ALREADY GRADED A+ - LATEST
UPDATE 2026-2027
During what trimester is a pregnant woman most at risk for adverse drug
reactions with potential long term consequences? - CORRECT ANSWER
1st trimester (fetus most at risk d/t rapid growth)
QUESTION : What is BEERS criteria? - CORRECT ANSWER
Recommendations of medications inappropriate for elderly (65 and older),
prescriber ultimately decides
QUESTION : What is the CYP450 (cytochrome P450) - CORRECT ANSWER
liver enzyme system where medications are metabolized, can either be inducers
or inhibitors and create drug-drug interactions
QUESTION : CYP450 inducers - CORRECT ANSWER Speed up
metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease
blood levels of drug), elevate CYP450 enzymes
QUESTION : CYP450 inducers pneumonic - CORRECT ANSWER
"Bullshit Crap GPS INDUCES rage"
UPDATED exam 2026
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QUESTION : CYP450 inducer drug names - CORRECT ANSWER
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin,
griseofulvin, phenobarbital, sulfonylureas
QUESTION : CYP450 inhibitors - CORRECT ANSWER inhibit
metabolism, increase blood levels of medications
QUESTION : CYP450 pneumonic - CORRECT ANSWER "VISA credit card
debt INHIBITS spending on designers like CK to look GQ"
QUESTION : CYP450 inhibitors drug names - CORRECT ANSWER
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole,
grapefruit juice, quinidine
QUESTION : Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of drugs? - CORRECT
ANSWER increase glomerular filtration rate leads to increase durg
excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
QUESTION : Examples of medications that can be teratogenic - CORRECT
ANSWER Antiepileptic drugs, antimicrobials such as tetracyclines and
fluoroquinolones, vitamin A in large doses, some anticoagulants, and hormonal
medications such as diethylstilbestrol (DES).
UPDATED exam 2026
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QUESTION : How is absorption of intramuscular medications different in
neonates? - CORRECT ANSWER slow and erratic due to low blood flow
in muscles first few days of life
QUESTION : Why is absorption of medication in the stomach increased in
infancy? - CORRECT ANSWER delayed gastric emptying
QUESTION : Some medications that should be avoided in the pediatric patient?
- CORRECT ANSWER glucocorticoids, discoloration of developing teeth
with tetracyclines, and kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
QUESTION : what should be included in medication administration patient
education? - CORRECT ANSWER dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
QUESTION : What are some things that put the elderly patient at higher risk for
adverse drug reactions? - CORRECT ANSWER reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
UPDATED exam 2026
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use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
QUESTION : How can healthcare providers decrease likelihood of an elderly
patient experiencing an adverse drug reaction? - CORRECT ANSWER
obtaining a thorough drug history that includes over-the-counter medications
considering pharmacokinetic and pharmacodynamics changes due to age
monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list
QUESTION : How can we promote medication adherence with elderly patients?
- CORRECT ANSWER simplifying drug regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems
UPDATED exam 2026