Midterm Exam: NR565/ NR 565
Advanced Pharmacology Care
Question and answers already passed
2025/2026
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for those with
diabetes and a risk score >7.5% - correct answer ✔ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or fibrate -
correct answer ✔Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from the small
intestine, without affecting triglycerides - correct answer ✔Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking cessation -
correct answer ✔Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-tolerated side
effects - correct answer ✔Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of preload and
afterload, and promotion of vasodilation - correct answer ✔Organic Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including grapefruit juice, HIV
protease inhibitors, macrolide antibiotics, azole antifungal drugs, and some CCB - correct answer
✔Ranolazine Contraindications
Avoid in children under 10 - correct answer ✔Statin Prescription Age
, Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - correct answer ✔CCB
Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with symptoms -
correct answer ✔HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac oxygen demand -
correct answer ✔CCB Stable Angina
Prescribe a BB to help with increased heart rate - correct answer ✔Nitro Patches Side Effect Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity - correct
answer ✔CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent for
relieving pain - correct answer ✔Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - correct answer ✔Gouty Arthritis
NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year - correct
answer ✔Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - correct answer ✔Colchicine Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - correct answer
✔Colchicine Adverse Effects
Advanced Pharmacology Care
Question and answers already passed
2025/2026
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for those with
diabetes and a risk score >7.5% - correct answer ✔ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or fibrate -
correct answer ✔Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from the small
intestine, without affecting triglycerides - correct answer ✔Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking cessation -
correct answer ✔Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-tolerated side
effects - correct answer ✔Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of preload and
afterload, and promotion of vasodilation - correct answer ✔Organic Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including grapefruit juice, HIV
protease inhibitors, macrolide antibiotics, azole antifungal drugs, and some CCB - correct answer
✔Ranolazine Contraindications
Avoid in children under 10 - correct answer ✔Statin Prescription Age
, Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - correct answer ✔CCB
Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with symptoms -
correct answer ✔HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac oxygen demand -
correct answer ✔CCB Stable Angina
Prescribe a BB to help with increased heart rate - correct answer ✔Nitro Patches Side Effect Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity - correct
answer ✔CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent for
relieving pain - correct answer ✔Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - correct answer ✔Gouty Arthritis
NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year - correct
answer ✔Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - correct answer ✔Colchicine Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - correct answer
✔Colchicine Adverse Effects
