NU 578
UNIT 5 EXAM
University of South Alabama.
High-Yield Qs & Verified Answers
with Rationales
This Exam Features:
This document includes 50 high-yield Exam
questions with verified answers and detailed
rationales for Unit 5 of NU 578 at the University of
South Alabama. It is designed to help students quickly review and
reinforce core concepts likely to appear on assessments. The
structured Q&A format supports focused exam preparation and
strengthens clinical reasoning and test-taking skills.
,Question 1
With the drug combination of Metronidazole, certain cephalosporins,
and alcohol you might see which reaction:
A. Anaphylactic reaction
B. Cardiac arrhythmias
C. Antabuse reaction
D. Enhanced anti-coagulant effect
Correct Answer: C. Antabuse reaction
Expert Rationale:
Metronidazole and some cephalosporins (such as cefotetan) can inhibit
aldehyde dehydrogenase, mimicking disulfiram (Antabuse) and causing a
reaction when combined with alcohol. Symptoms include flushing, nausea,
vomiting, and tachycardia. This disulfiram-like reaction is the expected
adverse interaction, and patients should be advised to avoid alcohol during
therapy.
---
Question 2
The most common adverse reactions to azoles are:
A. GI symptoms
B. Neuro symptoms
C. Integumentary symptoms
,D. Hematologic symptoms
Correct Answer: A. GI symptoms
Expert Rationale:
Azole antifungals commonly cause gastrointestinal side effects like nausea,
vomiting, abdominal pain, and diarrhea due to irritation of the GI mucosa.
Although other side effects can occur, GI symptoms are the most frequently
reported adverse effects, and patients should be counseled accordingly.
---
Question 3
A female patient who takes soy for its estrogenic effect is being treated
for sinusitis and experiencing hot flashes. The APN will consider what
data regarding soy?
A. Estrogenic effects on healing
B. Antibiotic antagonism of soy
C. Patient's sinusitis is misdiagnosed
D. Soy is not indicated for estrogen replacement
E. All the above are accurate
Correct Answer: E. All the above are accurate
Expert Rationale:
, Soy contains phytoestrogens that can modulate estrogenic activity potentially
affecting healing processes. Some antibiotics may interfere with soy
metabolism or effectiveness. Additionally, soy is not a formal estrogen
replacement therapy and may be insufficient to control menopausal
symptoms like hot flashes, suggesting possible misdiagnosis or inadequate
therapy.
---
Question 4
Aminoglycosides are usually given to treat:
A. Gram negative infections
B. Gram positive infections
C. Both a and b are correct since aminoglycosides are broad spectrum
Correct Answer: A. Gram negative infections
Expert Rationale:
Aminoglycosides exhibit potent bactericidal activity primarily against aerobic
gram-negative bacilli, including Pseudomonas and Enterobacteriaceae. They
have limited efficacy against gram-positive organisms unless combined with
cell wall-active agents like beta-lactams or vancomycin.
---
Question 5
UNIT 5 EXAM
University of South Alabama.
High-Yield Qs & Verified Answers
with Rationales
This Exam Features:
This document includes 50 high-yield Exam
questions with verified answers and detailed
rationales for Unit 5 of NU 578 at the University of
South Alabama. It is designed to help students quickly review and
reinforce core concepts likely to appear on assessments. The
structured Q&A format supports focused exam preparation and
strengthens clinical reasoning and test-taking skills.
,Question 1
With the drug combination of Metronidazole, certain cephalosporins,
and alcohol you might see which reaction:
A. Anaphylactic reaction
B. Cardiac arrhythmias
C. Antabuse reaction
D. Enhanced anti-coagulant effect
Correct Answer: C. Antabuse reaction
Expert Rationale:
Metronidazole and some cephalosporins (such as cefotetan) can inhibit
aldehyde dehydrogenase, mimicking disulfiram (Antabuse) and causing a
reaction when combined with alcohol. Symptoms include flushing, nausea,
vomiting, and tachycardia. This disulfiram-like reaction is the expected
adverse interaction, and patients should be advised to avoid alcohol during
therapy.
---
Question 2
The most common adverse reactions to azoles are:
A. GI symptoms
B. Neuro symptoms
C. Integumentary symptoms
,D. Hematologic symptoms
Correct Answer: A. GI symptoms
Expert Rationale:
Azole antifungals commonly cause gastrointestinal side effects like nausea,
vomiting, abdominal pain, and diarrhea due to irritation of the GI mucosa.
Although other side effects can occur, GI symptoms are the most frequently
reported adverse effects, and patients should be counseled accordingly.
---
Question 3
A female patient who takes soy for its estrogenic effect is being treated
for sinusitis and experiencing hot flashes. The APN will consider what
data regarding soy?
A. Estrogenic effects on healing
B. Antibiotic antagonism of soy
C. Patient's sinusitis is misdiagnosed
D. Soy is not indicated for estrogen replacement
E. All the above are accurate
Correct Answer: E. All the above are accurate
Expert Rationale:
, Soy contains phytoestrogens that can modulate estrogenic activity potentially
affecting healing processes. Some antibiotics may interfere with soy
metabolism or effectiveness. Additionally, soy is not a formal estrogen
replacement therapy and may be insufficient to control menopausal
symptoms like hot flashes, suggesting possible misdiagnosis or inadequate
therapy.
---
Question 4
Aminoglycosides are usually given to treat:
A. Gram negative infections
B. Gram positive infections
C. Both a and b are correct since aminoglycosides are broad spectrum
Correct Answer: A. Gram negative infections
Expert Rationale:
Aminoglycosides exhibit potent bactericidal activity primarily against aerobic
gram-negative bacilli, including Pseudomonas and Enterobacteriaceae. They
have limited efficacy against gram-positive organisms unless combined with
cell wall-active agents like beta-lactams or vancomycin.
---
Question 5
