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Sickle Cell Anemia NCLEX QUESTIONS AND ANSWERS GRADED A+

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Sickle Cell Anemia NCLEX QUESTIONS AND ANSWERS GRADED A+

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NCLEX Hematology-Immune
Course
NCLEX Hematology-Immune











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Institution
NCLEX Hematology-Immune
Course
NCLEX Hematology-Immune

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Uploaded on
January 23, 2026
Number of pages
142
Written in
2025/2026
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Sickle Cell Anemia NCLEX QUESTIONS
AND ANSWERS GRADED A+

A newly admitted client has sickle cell crisis. The nurse is planning care based on

assessment of the client. The client is complaining of severe pain in his feet and

hands. The pulse oximetry is 89. Which of the following interventions would be

implemented first? Assume that there are orders for each intervention.

a. Adjust the room temperature

b. Give a bolus of IV fluids

c. Start O2

d. Administer meperidine (Demerol) 75mg IV push - Correct answer-C

A 43-year-old African American male is admitted with sickle cell anemia. The

nurse plans to assess circulation in the lower extremities every 2 hours. Which of

the following outcome criteria would the nurse use?

A. Body temperature of 99°F or less

B. Toes moved in active range of motion


©COPYRIGHT 2025, ALL RIGHTS RESERVED 1

,C. Sensation reported when soles of feet are touched

D. Capillary refill of < 3 seconds - Correct answer-D

A 25-year-old male is admitted in sickle cell crisis. Which of the following

interventions would be of highest priority for this client?

A. Taking hourly blood pressures with mechanical cuff

B. Encouraging fluid intake of at least 200mL per hour

C. Position in high Fowler's with knee gatch raised

D. Administering Tylenol as ordered - Correct answer-B

A 14 year old girl has been hospitalized with Sickle Cell Anemia in vasoocclusive

crisis. Which of these Nursing diagnoses should receive priority in the Nursing

plan of care? --

A. Impaired social interaction --

B. Alteration in body image --

C. Pain --

D. Alteration in tissue perfusion - Correct answer-D

Which of the following foods would the nurse encourage the client in sickle cell

crisis to eat? --

©COPYRIGHT 2025, ALL RIGHTS RESERVED 2

,A. Peaches --

B. Cottage cheese --

C. Popsicles --

D. Lima beans - Correct answer-C

The male client with sickle cell anemia comes to the emergency room with a

temperature of 101.4 F and tells the nurse that he is having a sickle cell crisis.

Which diagnostic test should the nurse anticipate the emergency room doctor

ordering for the client? --

A. Spinal tap. --

B. Hemoglobin electrophoresis. --

C. Sickle-turbidity test (Sickledex). --

D. Blood cultures. - Correct answer-D

A Client in crisis should: - Correct answer-1. Management of Pain

2. Administration of oxygen

3. Promoting Hydration to decrease blood viscocity

4. Monitor for



©COPYRIGHT 2025, ALL RIGHTS RESERVED 3

, The nurse is teaching a group of parents whose children have sickle cell anemia.

When a parent asks the cause of the symptoms, the nurse responds with which of

the following? - Correct answer-"Sickled cells clump in the smaller blood vessels

and obstruct blood flow."




Rationale:

All the symptoms of sickle cell are a result of the clumping of the sickled cells in

the microvasculature, causing obstruction of blood flow. The other statements are

inaccurate.

A child with suspected sickle cell disease (SCD) is in the clinic for laboratory

studies. The parents ask the nurse what results will tell the physician that their

child has SCD. The nurse responds that which of the following is increased in this

disease? - Correct answer-Reticulocyte count




Rationale:

The reticulocyte count will be increased because the life span of sickled red blood

cells is shortened. Hemoglobin, hematocrit, and platelet levels will be decreased.




©COPYRIGHT 2025, ALL RIGHTS RESERVED 4
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