Pharm Quiz 2 with Thyroid and Pneumonia Questions Verified Answers Rated A+ Package with Solution 2025/ 2026 Complete Pharmacology Nursing Study Resource

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Terms in this set (671) Original




High TSH, low T4 Hypothyroidism



Weight gain, fatigue, hypothyroidism
bradycardia,
constipation, cold
intolerance




Hypothyroidism goals of Improve symptoms, normalize TSH secretion,
therapy reduce goiter size (if present), avoid overtreatment



Gold standard treatment Levothyroxine
for hypothyroidism?



How do you dose Weight based (and lower fixed dose in
levothyroxine? elderly/coronary heart disease)



Should you take No (food will decrease the absorption). Take 30-60
levothyroxine with food? min prior to breakfast.



Over-replacement of atrial fib and accelerated bone loss
levothyroxine can lead
to...



Do not admin calcium or iron products
levothyroxine within 4
hours of...



Check xxx 4-8 weeks TSH
after initiation or
adjustment of
levothyroxine dose




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Test 3: You have 4 weeks
increased the dose of a
patient's levothyroxine.
What time frame should
be the earliest in which
you would recheck a
patient's thyroid
stimulating hormone
(TSH)?



Is brand or generic Considered equivalent by the FDA. However,
levothyroxine better? multiple guidelines disagree.



IV dosing of 75
Levothyroxine is xxx% of
oral dosing




Why is desiccated Desiccated thyroid extract contains T4:T3 in a ratio
thyroid extract not of 4:1
recommended to treat
for hypothyroidism?



What is the half life of 18 hours
Liothyronine (T3)?



Is Liothyronine No because of toxicity concerns
recommended as
monotherapy?



Which is better, T4/T3 Studies show combo has no benefit over T4 alone
combo therapy or T4
alone?



When should you not Euthyroid patients for tx of obesity, weight loss, or
treat hypothyroidism? depression



TSH elevated, T4 normal subclinical hypothyroidism



Should you treat mild- Decision to treat is based on the individual (age,
mod subclinical symptoms, CV risk)
hypothyroidism?



Should you treat severe Yes. Consider tx with Levothyroxine.
subclinical
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subc ca
hypothyroidism?



Meds that cause Amiodarone
hypothyroidism Lithium
Interferon alpha
Interleukin 2
Tyrosine kinase inhibitors
Checkpoint inhibitors



In med-induced Treat with levothyroxine and monitor TSH every 6-
hypothyroidism, what is 12 months
the treatment and what
should you monitor?




Severe hypothyroidism -- Myxedema
> decreased mental
status, hypothermia,
hypotension,
bradycardia,
hyponatremia,
hypoventilation



Treatment for myxedema -Stress dose of IV glucocorticoids
-High dose load of IV Levothyroxine (T4) followed
by standard dosing
-Liothyronine (T3) until recovery



Low TSH, high T4 Hyperthyroidism



Weight loss, sweating, Hyperthyroidism
anxiety, heat intolerance,
tachycardia



Treatment options Hyperthyroidism
include:
-Thionamides
-Radioactive Iodine
-Surgery
-Beta blockers
-Iodides



Methimazole, Thionamides
Propylthiouracil



MOA: Inhibit thyroid Thionamides
peroxidase, block
synthesis of T3 and T4
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