RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
Which of the following statements is true regarding B cells?
B cells stimulate T-helper cells through MHC peptides
B cells directly activate the complement cascade
B cells are part of the innate immune system
B cells stimulate T-helper cells to produce antibodies CORRECT ANSWERS
B cells stimulate T-helper cells through MHC peptides
Decreased serum complement is associated with autoimmune diseases such as systemic lupus
erythematosus (SLE).
True
False CORRECT ANSWERS
True
C3 and C4 can be measured in the blood:
•Increased values: cancer, infection, UC
•Decreased values: liver disease, autoimmune disease (lupus), kidney disease.
Which of the following are considered to be environmental triggers for autoimmunity?
Diet and lifestyle
UV Radiation
Infections
Only diet and lifestyle and infections are considered to be common environmental triggers for
autoimmunity
All of the above are triggers for autoimmunity CORRECT ANSWERS
All of the above are triggers for autoimmunity
Environmental triggers for autoimmunity:
•Hormone production
•Infections
•Microbial flora (skin, GI, vaginal...etc)
•UV radiation
,RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
•Toxic exposure (heavy metals, pharmaceuticals...etc)
•Diet and lifestyle (obesity, food allergies...etc)
Elevated ferritin levels are often present in chronic inflammation.
True
False
Ferritin increases in acute inflammation, but chronic inflammation will deplete iron levels over
time making ferritin levels in the serum low.
Low ferritin: iron deficiency, chronic inflammation
High ferritin: iron overload (hemochromatosis), cancer, acute inflammation, infection
CORRECT ANSWERS
False
Ferritin increases in acute inflammation, but chronic inflammation will deplete iron levels over
time making ferritin levels in the serum low.
Low ferritin: iron deficiency, chronic inflammation
High ferritin: iron overload (hemochromatosis), cancer, acute inflammation, infection
Which of the following is NOT considered to be an immune system dysregulation in
the adaptive immune system?
Molecular mimicry
Over activation of T-cells
Lack of Treg induction by dendritic cells
Problems with central tolerance in the thymus CORRECT ANSWERS
Lack of Treg induction by dendritic cells
From the immune system dysregulation slide:
Innate Immune Response
Overexpression of TLRs by spontaneous gene duplication
,RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
Lack of TReg induction by dendritic cells
Failure to properly clear apoptotic cells
Over activation of complement components
Adaptive Immune Response
Reduction in TReg activity
Problems with central tolerance in the thymus
Overactivation of T-cells
Molecular mimicry
Which of the following is NOT commonly considered to be an immunogenic determinant:
Molecular size of antigen
Reduction in Treg activity
Antigenic determinants (epitopes)
Chemical-structural complexity
Immunogenic Determinants:
•Foreignness
•Molecular size
•Chemical-structural complexity
•Antigenic determinants (epitopes)
•Dosage, route and timing of antigen administration
•Genetic constitution of the host (HLA genes)
•Adjuvants - or immune system enhancers CORRECT ANSWERS
Reduction in Treg activity
Immunogenic Determinants:
•Foreignness
•Molecular size
, RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
•Chemical-structural complexity
•Antigenic determinants (epitopes)
•Dosage, route and timing of antigen administration
•Genetic constitution of the host (HLA genes)
•Adjuvants - or immune system enhancers
Which of the following is NOT a main function of the innate immune response?
Trigger the adaptive immune response
Clear foreign and potentially detrimental materials
Activate complement
Immunologic memory CORRECT ANSWERS
Immunologic memory
The main functions of the innate immune response:
Clear foreign and potentially detrimental materials
Recruit, activate and stimulate effector activity of immune cells
Activate complement
Enhances and modulates humoral and cellular immune responses
Trigger the adaptive immune response
Cell signaling and antigen presentation
Major histocompatibility complexes (MHC) are also known as which of the following:
T-cell Receptors (TCRs)
Toll-like receptors (TLRs)
Pattern recognition receptors (PRRs)
Human leukocyte antigens (HLAs) CORRECT ANSWERS
Human leukocyte antigens (HLAs)
- MHC proteins in humans are known as human leukocyte antigens (HLAs)
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
Which of the following statements is true regarding B cells?
B cells stimulate T-helper cells through MHC peptides
B cells directly activate the complement cascade
B cells are part of the innate immune system
B cells stimulate T-helper cells to produce antibodies CORRECT ANSWERS
B cells stimulate T-helper cells through MHC peptides
Decreased serum complement is associated with autoimmune diseases such as systemic lupus
erythematosus (SLE).
True
False CORRECT ANSWERS
True
C3 and C4 can be measured in the blood:
•Increased values: cancer, infection, UC
•Decreased values: liver disease, autoimmune disease (lupus), kidney disease.
Which of the following are considered to be environmental triggers for autoimmunity?
Diet and lifestyle
UV Radiation
Infections
Only diet and lifestyle and infections are considered to be common environmental triggers for
autoimmunity
All of the above are triggers for autoimmunity CORRECT ANSWERS
All of the above are triggers for autoimmunity
Environmental triggers for autoimmunity:
•Hormone production
•Infections
•Microbial flora (skin, GI, vaginal...etc)
•UV radiation
,RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
•Toxic exposure (heavy metals, pharmaceuticals...etc)
•Diet and lifestyle (obesity, food allergies...etc)
Elevated ferritin levels are often present in chronic inflammation.
True
False
Ferritin increases in acute inflammation, but chronic inflammation will deplete iron levels over
time making ferritin levels in the serum low.
Low ferritin: iron deficiency, chronic inflammation
High ferritin: iron overload (hemochromatosis), cancer, acute inflammation, infection
CORRECT ANSWERS
False
Ferritin increases in acute inflammation, but chronic inflammation will deplete iron levels over
time making ferritin levels in the serum low.
Low ferritin: iron deficiency, chronic inflammation
High ferritin: iron overload (hemochromatosis), cancer, acute inflammation, infection
Which of the following is NOT considered to be an immune system dysregulation in
the adaptive immune system?
Molecular mimicry
Over activation of T-cells
Lack of Treg induction by dendritic cells
Problems with central tolerance in the thymus CORRECT ANSWERS
Lack of Treg induction by dendritic cells
From the immune system dysregulation slide:
Innate Immune Response
Overexpression of TLRs by spontaneous gene duplication
,RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
Lack of TReg induction by dendritic cells
Failure to properly clear apoptotic cells
Over activation of complement components
Adaptive Immune Response
Reduction in TReg activity
Problems with central tolerance in the thymus
Overactivation of T-cells
Molecular mimicry
Which of the following is NOT commonly considered to be an immunogenic determinant:
Molecular size of antigen
Reduction in Treg activity
Antigenic determinants (epitopes)
Chemical-structural complexity
Immunogenic Determinants:
•Foreignness
•Molecular size
•Chemical-structural complexity
•Antigenic determinants (epitopes)
•Dosage, route and timing of antigen administration
•Genetic constitution of the host (HLA genes)
•Adjuvants - or immune system enhancers CORRECT ANSWERS
Reduction in Treg activity
Immunogenic Determinants:
•Foreignness
•Molecular size
, RHEUMATOLOGY (QUIZZES 1-8) EXAM QUESTIONS AND
ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE
SOLUTION ALL ANSWERS 100% CORRECT VERIFIED BEST
GRADED A+ FOR SUCCESS
•Chemical-structural complexity
•Antigenic determinants (epitopes)
•Dosage, route and timing of antigen administration
•Genetic constitution of the host (HLA genes)
•Adjuvants - or immune system enhancers
Which of the following is NOT a main function of the innate immune response?
Trigger the adaptive immune response
Clear foreign and potentially detrimental materials
Activate complement
Immunologic memory CORRECT ANSWERS
Immunologic memory
The main functions of the innate immune response:
Clear foreign and potentially detrimental materials
Recruit, activate and stimulate effector activity of immune cells
Activate complement
Enhances and modulates humoral and cellular immune responses
Trigger the adaptive immune response
Cell signaling and antigen presentation
Major histocompatibility complexes (MHC) are also known as which of the following:
T-cell Receptors (TCRs)
Toll-like receptors (TLRs)
Pattern recognition receptors (PRRs)
Human leukocyte antigens (HLAs) CORRECT ANSWERS
Human leukocyte antigens (HLAs)
- MHC proteins in humans are known as human leukocyte antigens (HLAs)
