1|Page
ADVANCED PHARMACOLOGY
FINAL 2026-2027 EXAM UTA| ALL
QUESTIONS AND CORRECT
DETAILED ANSWERS | RATED A + |
NEW AND REVISED
Which of the following is a common adverse effect of
trimethoprim/ sulfamethoxazole (TMP/SMZ)?
•A. Decreased prothrombin times in patients receiving warfarin
•B. Skin reactions
•C. Tendon rupture
•D. Constipation - ANSWER- B. Skin reactions
Which cephalosporins cause bleeding tendencies? - ANSWER-
Cefotetan, ceftriaxone
Which cephalosporins induced alcohol intolerance? -
ANSWER- Cefotetan, cefazolin
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Which macrolide is least likely to cause QT prolongation? -
ANSWER- Azithromycin
Which of the following cephalosporins has activity against gram
negative anaerobic pathogens such as Bacteroides fragilis? -
ANSWER- Cefoxitin [Mefoxin] (2nd generation)
A 20 year old comes to the office with UTI. Based on symptoms
and a UA, she is diagnosed with a UTI. Cultures reveal
Enterococcus faecalis that is sensitive to all antibiotics usually
tested for potential treatment. Which of the following is an
appropriate oral option to treat the UTI in this patient?
•Cephalexin
•Vancomycin
•Levofloxacin
•Amoxicillin - ANSWER- Amoxicillin
The first line antibiotic for a patient with comorbidities [or who
is immunosuppressed] who has pneumonia and can be treated as
an outpatient would be: - ANSWER- Levofloxacin
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John is a 4week old infant who has been diagnosed with
Chlamydial pneumonia. An appropriate treatment for his
pneumonia would be: - ANSWER- Erythromycin
Which of the following is the primary method of B-lactam
resistance with Streptococcus pneumoniae?
•Inactivation by bacterial enzymes
•Production of PBPs
•Modification of target site
•Decreased drug levels due to changes in permeability -
ANSWER- Modification of target site
An 80 year old patient will begin taking Cefdinir [Omnicef].
Before initiating therapy, the nurse practitioner should order: -
ANSWER- Creatinine clearance
A patient on long term Clindamycin therapy should be warned
of which side effects? - ANSWER- Clostridium difficile
diarrhea
What is maximum amount of Sumatriptan that can be taken in 1
day? - ANSWER- 200 mg
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The ability of the anesthetic to penetrate the axon membrane is
determined by 3 properties. What are they? - ANSWER-
Molecular size
Lipid solubility
Degree of ionization at tissue pH
Why is epinephrine given with local anesthetics? - ANSWER-
•Decreases local blood flow
•Delays systemic absorption of the anesthetic
•Prolongs anesthesia
•Reduces the risk of toxicity
What is the most widely used local anesthetic? - ANSWER-
Lidocaine
What is a possible fatal reaction to benzocaine? - ANSWER-
Methemoglobinemia
What is included in application guidelines for topical
anesthetics? Check all that apply.
•A. Apply largest amount needed
•B. Apply to large areas
ADVANCED PHARMACOLOGY
FINAL 2026-2027 EXAM UTA| ALL
QUESTIONS AND CORRECT
DETAILED ANSWERS | RATED A + |
NEW AND REVISED
Which of the following is a common adverse effect of
trimethoprim/ sulfamethoxazole (TMP/SMZ)?
•A. Decreased prothrombin times in patients receiving warfarin
•B. Skin reactions
•C. Tendon rupture
•D. Constipation - ANSWER- B. Skin reactions
Which cephalosporins cause bleeding tendencies? - ANSWER-
Cefotetan, ceftriaxone
Which cephalosporins induced alcohol intolerance? -
ANSWER- Cefotetan, cefazolin
,2|Page
Which macrolide is least likely to cause QT prolongation? -
ANSWER- Azithromycin
Which of the following cephalosporins has activity against gram
negative anaerobic pathogens such as Bacteroides fragilis? -
ANSWER- Cefoxitin [Mefoxin] (2nd generation)
A 20 year old comes to the office with UTI. Based on symptoms
and a UA, she is diagnosed with a UTI. Cultures reveal
Enterococcus faecalis that is sensitive to all antibiotics usually
tested for potential treatment. Which of the following is an
appropriate oral option to treat the UTI in this patient?
•Cephalexin
•Vancomycin
•Levofloxacin
•Amoxicillin - ANSWER- Amoxicillin
The first line antibiotic for a patient with comorbidities [or who
is immunosuppressed] who has pneumonia and can be treated as
an outpatient would be: - ANSWER- Levofloxacin
,3|Page
John is a 4week old infant who has been diagnosed with
Chlamydial pneumonia. An appropriate treatment for his
pneumonia would be: - ANSWER- Erythromycin
Which of the following is the primary method of B-lactam
resistance with Streptococcus pneumoniae?
•Inactivation by bacterial enzymes
•Production of PBPs
•Modification of target site
•Decreased drug levels due to changes in permeability -
ANSWER- Modification of target site
An 80 year old patient will begin taking Cefdinir [Omnicef].
Before initiating therapy, the nurse practitioner should order: -
ANSWER- Creatinine clearance
A patient on long term Clindamycin therapy should be warned
of which side effects? - ANSWER- Clostridium difficile
diarrhea
What is maximum amount of Sumatriptan that can be taken in 1
day? - ANSWER- 200 mg
, 4|Page
The ability of the anesthetic to penetrate the axon membrane is
determined by 3 properties. What are they? - ANSWER-
Molecular size
Lipid solubility
Degree of ionization at tissue pH
Why is epinephrine given with local anesthetics? - ANSWER-
•Decreases local blood flow
•Delays systemic absorption of the anesthetic
•Prolongs anesthesia
•Reduces the risk of toxicity
What is the most widely used local anesthetic? - ANSWER-
Lidocaine
What is a possible fatal reaction to benzocaine? - ANSWER-
Methemoglobinemia
What is included in application guidelines for topical
anesthetics? Check all that apply.
•A. Apply largest amount needed
•B. Apply to large areas
