WGU D115 Advanced Pathophysiology Practice Exam – Updated 2026 with Detailed Answers

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WGU D115 OA ADVANCED PATHOPHYSIOLOGY EXAM 2026 | ACTUAL EXAM QUESTIONS WITH
DETAILED ANSWERS WITH RATIONALES AND A READINESS PRACTICE EXAM WITH A STUDY
GUIDE RATED A GRADE.



Describe how your body responds to an infection. - CORRECT ANSWER T cells
produce cytokines, which stimulate B cells. B cells produce antibodies.



QUESTION : Identify role of DNA changes in congenital abnormalities. - CORRECT
ANSWER Mutations in genes or chromosomal abnormalities



QUESTION : How does development disrupts congenital abnormalities? - CORRECT
ANSWER Alterations of DNA



QUESTION : Describes factors that disrupt homeostasis and how disruptions affect wellbeing.
- CORRECT ANSWER (ex) Fluid and electrolyte shifts can cause n/v or dysrhythmias.



QUESTION : Explain RAAS - CORRECT ANSWER Renin-angiotensin-aldosterone
system
1. Reduce blood flow causes kidneys to release renin
> produce angiotensin I > converts angiotensin I to angiotensin II > vasoconstriction > release
aldosterone > kidneys conserve sodium and water > Result less water lost in urine and blood
pressure maintained.



QUESTION : DKA - CORRECT ANSWER increased anion gap, decreased HCO3



QUESTION : How do kidneys compensate for alkalosis - CORRECT ANSWER retain H
and excrete HCO3



QUESTION : Untreated acidosis leads to an increase in which electrolyte? - CORRECT
ANSWER Potassium


2026 2027 GRADED A+

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QUESTION : West Nile Virus - CORRECT ANSWER Transmitted through the bite of an
infected mosquito. Severe signs and symptoms; high fever, headache and stiff neck



QUESTION : Lyme disease - CORRECT ANSWER Tick-borne disease caused by the
spirochete Borrelia burgdorferi.



QUESTION : Erythema infectiosum - CORRECT ANSWER a febrile upper respiratory
illness in a child followed by the sudden appearance of red, flushed cheeks, "fifth disease"



QUESTION : Obesity ad diabetes are risk factors for having a child with _____. - CORRECT
ANSWER Spina bifida



QUESTION : Trousseau's sign - CORRECT ANSWER arm/carpal spasm associated with
hypocalcemia



QUESTION : Cause and sign of spina bifida - CORRECT ANSWER results from failure
of neural tube to close. sign - fluid filled sac on lower back.



QUESTION : hemophilia is more common in - CORRECT ANSWER males



QUESTION : Prenatal exposure to alcohol includes - CORRECT ANSWER ND-PAE,
decreased brain function, FAS



QUESTION : Connective vs muscle tissue disorders - CORRECT ANSWER Connective-
RA, Scleroderma, Lupus
Muscle - MS, Muscular dystrophy, Myasthenia Gravia




2026 2027 GRADED A+

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QUESTION : Describe Lupus - CORRECT ANSWER Inflammatory disorder
characterized by joint pain and butterfly rash



QUESTION : Describe Myasthenia Gravis - CORRECT ANSWER It is an autoimmune
disorder where antibodies attack own Ach receptors. This causes weakness of skeletal
muscles over the course of the day, along with ptosis, double vision, and difficulty
swallowing.



QUESTION : dermatitis - CORRECT ANSWER inflammation of the skin



QUESTION : eczema - CORRECT ANSWER noninfectious, inflammatory skin disease
characterized by redness, blisters, scabs, and itching



QUESTION : decubitus ulcer - CORRECT ANSWER sore caused by lying down for long
periods of time



QUESTION : Fungal infections - CORRECT ANSWER superficial, localized skin
conditions or deep tissue infections caused by exposure to spores


may or may not be transmitted



QUESTION : benign neoplasm - CORRECT ANSWER noncancerous growths,
stationary, distinct borders



QUESTION : malignant neoplasm - CORRECT ANSWER uncontrolled new tissue
growth, irregular borders, spreads



QUESTION : Osteoporosis - CORRECT ANSWER The loss of bone mass often due to
age, causing the bones to become porous, brittle, and easily fractured.




2026 2027 GRADED A+