HEMATO LOGY
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Test Bank For Rodak's Hematology: Clinical
Principles and Applications, 7th Edition by;
Elaine M. Keohane| All Chapters 1-43| Latest
Edition
Page 1 of 257
, HEMATO LOGY
Stuvia.com - Th e Marketplac e to B uy an d Sell your Study Material
TABLE OF CONTENTS
Part I: Introduction to Hematology
1. An Overview of Clinical Laboratory Hematology
2. Patient Safety in Hematology and Hemostasis
3. Quality Assurance in Hematology and Hemostasis Testing
PART II: Blood Cell Production, Structure, and Function
4. Cell Structure and Function
5. Hematopoiesis
6. Erythrocyte Production and Destruction
7. Erythrocyte Metabolism and Membrane Structure and Function
8. Hemoglobin Metabolism
9. Iron Kinetics and Laboratory Assessment
10. Leukocyte Development, Kinetics, and Functions
11. Platelet Production, Structure, and Function
PART III: Laboratory Evaluation of Blood Cells
12. Manual, Semiautomated, and Point-of-Care Testing in Hematology
13. Automated Blood Cell Analysis
14. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count
15. Bone Marrow Examination
PART IV: Erythrocyte Disorders
16. Anemias: Red Blood Cell Morphology and Approach to Diagnosis
17. Disorders of Iron Kinetics and Heme Metabolism
18. Anemias Caused by Defects of DNA Metabolism
19. Bone Marrow Failure
20. Introduction to Increased Destruction of Erythrocytes
21. Intrinsic Defects Leading to Increased Erythrocyte Destruction
22. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Nonimmune Causes
23. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Immune Causes
24. Hemoglobinopathies (Structural Defects in Hemoglobin)
25. Thalassemias
PART V: Leukocyte Disorders
26. Nonmalignant Leukocyte Disorders
27. Introduction to Hematologic Neoplasms
28. Flow Cytometric Analysis in Hematologic Disorders
29. Molecular Diagnostics in Hematopathology
30. Cytogenetics
31. Acute Leukemias
32. Myeloproliferative Neoplasms
33. Myelodysplastic Neoplasms
34. Mature Lymphoid Neoplasms
PART VI: Hemostasis and Thrombosis
35. Normal Hemostasis
36. Hemorrhagic Disorders and Laboratory Assessment
37. Qualitative Disorders of Platelets and Vasculature
38. Quantitative Disorders of Platelets: Thrombocytopenia and Thrombocytosis
39. Thrombotic Disorders and Laboratory Assessment
40. Antithrombotic Therapies and Laboratory Assessment
41. Laboratory Evaluation of Hemostasis
42. Hemostasis and Coagulation Instrumentation
PART VII: Hematology and Hemostasis in Selected Populations
43. Hematology and Hemostasis in the Pediatric, Pregnant, Geriatric, and Transgender Populations
Page 2 of 257
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1. chapter 01-01
hematology is the study of:
*a. blood cells.
b. serum electrolytes.
c. plasma hormone levels.
d. bacteria in the blood.
general feedback:
hematology is the study of blood cells*red blood cells, white blood cells, and platelets.
plasma and serum electrolytes and hormone levels are evaluated in various subdivisions of clinical chemistry, and bacteria
are evaluated in clinical microbiology.
2. chapter 01-02
the morphology of blood cells isimportant to evaluate:
a. every time a complete blood count (cbc)is requested on a patient.
b. when an instrument-generated flag isobtained.
*c. when a profiling instrument result is abnormal.
d. when the white count is elevated.
general feedback:
every laboratory must determine*based on its instrumentation, needs of the clinician and other parameter
flags that alert the medical laboratory scientist to the necessity for further evaluation* when it is necessary to evaluate cell
morphology. many instrument-generated flags, although useful, may not require review. if an automated cbcdoes not suggest
the need, no reason exists to evaluate the blood film, even if the white count is elevated.
3. chapter 01-03
who is ultimately responsible for determining the specimen integrity before analysis?
*a. medical laboratory professional
b. nursing staff
c. phlebotomist
d. specimen-processing personnel
general feedback:
the medical laboratory scientist is responsible for ensuring the integrity of a specimen before analysis. only
he or she can judge whether the specimen is acceptable so that valid results can beobtained. acceptable criteria include such
things as type of specimen for the test ordered (e.g., blood, serum, urine); appropriate additive present (if needed) and amount
of specimen relative to the additive; time interval since obtained; and presence or absence of hemolysis, lipemia, and other
similar conditions. none of the other personnel named have the education and understanding to fully make that judgment.
Page 3 of 257
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4. chapter 01-04 hematocrit is also
called:
a. white cell count.
b. bone marrowexamination.
c. red blood cell (rbc) count.
*d. packed red cell volume.
general feedback:
historically the hematocrit was determined by centrifuging an aliquot of anticoagulated whole blood under
specified conditions (e.g., centrifugal force, capillary tube length, and bore diameter) and then determining the ratio of the space
occupied by the packed red cells compared with that of the entire blood volume in the capillary tube, often expressed as a
percentage. hence, it is also called the packed red cell volume.
5. chapter 01-05
the primary function of platelets is to:
a. defend the body against bacterial invasion.
b. carry oxygen to tissues.
*c. facilitate blood clotting.
d. regulate acid-base balance.
general feedback:
whenever disruption occurs to a blood vessel so that bleeding results, platelets respond initially to stop the
bleeding in small vessels; they also play an integral role in facilitating the formation of a blood clot. white cells defend
against bacterial invasion; red cells (i.e., hemoglobin) carry oxygen to tissues; and a complex interaction of plasma
electrolytes, proteins, and carbon dioxide participates in acid-base balance.
6. chapter 01-06
which of the following can be evaluated only through the microscopic examination of a stained blood film?
a. white blood cell(wbc) count
b. reticulocyte count
c. hemoglobin concentration
*d. presence or absence of cytoplasmic inclusions
general feedback:
making and staining a blood film and then placing it under a microscope allow the medical laboratory
scientist to evaluate the morphology of blood cells and examine them for the presence or absence of blood cell inclusions.
these inclusions are important for cell identification and, when abnormal inclusions arepresent, sometimes provide “clues” as
to the cause of disease. all the other parameters mentioned areor can beperformed using an automated hematology
instrument, including reticulocyte counting.
3
Page 4 of 257
Stuvia.com - Th e Marketplac e to B uy an d Sell your Study Material
Test Bank For Rodak's Hematology: Clinical
Principles and Applications, 7th Edition by;
Elaine M. Keohane| All Chapters 1-43| Latest
Edition
Page 1 of 257
, HEMATO LOGY
Stuvia.com - Th e Marketplac e to B uy an d Sell your Study Material
TABLE OF CONTENTS
Part I: Introduction to Hematology
1. An Overview of Clinical Laboratory Hematology
2. Patient Safety in Hematology and Hemostasis
3. Quality Assurance in Hematology and Hemostasis Testing
PART II: Blood Cell Production, Structure, and Function
4. Cell Structure and Function
5. Hematopoiesis
6. Erythrocyte Production and Destruction
7. Erythrocyte Metabolism and Membrane Structure and Function
8. Hemoglobin Metabolism
9. Iron Kinetics and Laboratory Assessment
10. Leukocyte Development, Kinetics, and Functions
11. Platelet Production, Structure, and Function
PART III: Laboratory Evaluation of Blood Cells
12. Manual, Semiautomated, and Point-of-Care Testing in Hematology
13. Automated Blood Cell Analysis
14. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count
15. Bone Marrow Examination
PART IV: Erythrocyte Disorders
16. Anemias: Red Blood Cell Morphology and Approach to Diagnosis
17. Disorders of Iron Kinetics and Heme Metabolism
18. Anemias Caused by Defects of DNA Metabolism
19. Bone Marrow Failure
20. Introduction to Increased Destruction of Erythrocytes
21. Intrinsic Defects Leading to Increased Erythrocyte Destruction
22. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Nonimmune Causes
23. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Immune Causes
24. Hemoglobinopathies (Structural Defects in Hemoglobin)
25. Thalassemias
PART V: Leukocyte Disorders
26. Nonmalignant Leukocyte Disorders
27. Introduction to Hematologic Neoplasms
28. Flow Cytometric Analysis in Hematologic Disorders
29. Molecular Diagnostics in Hematopathology
30. Cytogenetics
31. Acute Leukemias
32. Myeloproliferative Neoplasms
33. Myelodysplastic Neoplasms
34. Mature Lymphoid Neoplasms
PART VI: Hemostasis and Thrombosis
35. Normal Hemostasis
36. Hemorrhagic Disorders and Laboratory Assessment
37. Qualitative Disorders of Platelets and Vasculature
38. Quantitative Disorders of Platelets: Thrombocytopenia and Thrombocytosis
39. Thrombotic Disorders and Laboratory Assessment
40. Antithrombotic Therapies and Laboratory Assessment
41. Laboratory Evaluation of Hemostasis
42. Hemostasis and Coagulation Instrumentation
PART VII: Hematology and Hemostasis in Selected Populations
43. Hematology and Hemostasis in the Pediatric, Pregnant, Geriatric, and Transgender Populations
Page 2 of 257
, HEMATO LOGY
Stuvia.com - Th e Marketplac e to B uy an d Sell your Study Material
1. chapter 01-01
hematology is the study of:
*a. blood cells.
b. serum electrolytes.
c. plasma hormone levels.
d. bacteria in the blood.
general feedback:
hematology is the study of blood cells*red blood cells, white blood cells, and platelets.
plasma and serum electrolytes and hormone levels are evaluated in various subdivisions of clinical chemistry, and bacteria
are evaluated in clinical microbiology.
2. chapter 01-02
the morphology of blood cells isimportant to evaluate:
a. every time a complete blood count (cbc)is requested on a patient.
b. when an instrument-generated flag isobtained.
*c. when a profiling instrument result is abnormal.
d. when the white count is elevated.
general feedback:
every laboratory must determine*based on its instrumentation, needs of the clinician and other parameter
flags that alert the medical laboratory scientist to the necessity for further evaluation* when it is necessary to evaluate cell
morphology. many instrument-generated flags, although useful, may not require review. if an automated cbcdoes not suggest
the need, no reason exists to evaluate the blood film, even if the white count is elevated.
3. chapter 01-03
who is ultimately responsible for determining the specimen integrity before analysis?
*a. medical laboratory professional
b. nursing staff
c. phlebotomist
d. specimen-processing personnel
general feedback:
the medical laboratory scientist is responsible for ensuring the integrity of a specimen before analysis. only
he or she can judge whether the specimen is acceptable so that valid results can beobtained. acceptable criteria include such
things as type of specimen for the test ordered (e.g., blood, serum, urine); appropriate additive present (if needed) and amount
of specimen relative to the additive; time interval since obtained; and presence or absence of hemolysis, lipemia, and other
similar conditions. none of the other personnel named have the education and understanding to fully make that judgment.
Page 3 of 257
, HEMATO LOGY
Stuvia.com - Th e Marketplac e to B uy an d Sell your Study Material
4. chapter 01-04 hematocrit is also
called:
a. white cell count.
b. bone marrowexamination.
c. red blood cell (rbc) count.
*d. packed red cell volume.
general feedback:
historically the hematocrit was determined by centrifuging an aliquot of anticoagulated whole blood under
specified conditions (e.g., centrifugal force, capillary tube length, and bore diameter) and then determining the ratio of the space
occupied by the packed red cells compared with that of the entire blood volume in the capillary tube, often expressed as a
percentage. hence, it is also called the packed red cell volume.
5. chapter 01-05
the primary function of platelets is to:
a. defend the body against bacterial invasion.
b. carry oxygen to tissues.
*c. facilitate blood clotting.
d. regulate acid-base balance.
general feedback:
whenever disruption occurs to a blood vessel so that bleeding results, platelets respond initially to stop the
bleeding in small vessels; they also play an integral role in facilitating the formation of a blood clot. white cells defend
against bacterial invasion; red cells (i.e., hemoglobin) carry oxygen to tissues; and a complex interaction of plasma
electrolytes, proteins, and carbon dioxide participates in acid-base balance.
6. chapter 01-06
which of the following can be evaluated only through the microscopic examination of a stained blood film?
a. white blood cell(wbc) count
b. reticulocyte count
c. hemoglobin concentration
*d. presence or absence of cytoplasmic inclusions
general feedback:
making and staining a blood film and then placing it under a microscope allow the medical laboratory
scientist to evaluate the morphology of blood cells and examine them for the presence or absence of blood cell inclusions.
these inclusions are important for cell identification and, when abnormal inclusions arepresent, sometimes provide “clues” as
to the cause of disease. all the other parameters mentioned areor can beperformed using an automated hematology
instrument, including reticulocyte counting.
3
Page 4 of 257
