Haveles: Applied Pharmacology for the Dental Hygienist, 10th Edition
X$ X$ X$ X$ X$ X$ X$ X$
MULTIPLE CHOICE X$
1. Knowledge of pharmacology aids the dental professional in X$ X$ X$ X$ X$ X$ X$
a. obtaining a patient’s health history. X$ X$ X$ X$
b. administering drugs in the office. X$ X$ X$ X$
c. handling emergency situations. X$ X$
d. selection of a nonprescription medication. X$ X$ X$ X$
e. All of the above. X$ X$ X$
ANS: E X $
All of the choices are true. Because many of our patients are being treated with drugs, knowledge o
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
f pharmacology helps in understanding and interpreting patients’ responses to health history question
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
s. Knowledge of the therapeutic and adverse effects of medications obviously helps in their proper a
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
dministration in the office. Emergency situations may be caused by drugs or treated by drugs; thus,
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
knowledge of pharmacology is of great help, especially because a rapid response is sometimes requi
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
red. A clear understanding of the concepts of drug action, drug handling by the body, and drug inter
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
actions will allow the dental practitioner to make proper judgments and grasp the concepts relevant
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
to new drug therapies on the market.
X$ X$ X$ X$ X$ X$
DIF: Application
REF: Role of the Dental Hygienist (Medication/Health History), Role of the Dental Hygienist (Medicati
X $ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
on Administration), Role of the Dental Hygienist (Emergency Situations), Role of the Dental Hygienist (
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
Nonprescription Medication) | pp. 2-3 OBJ: 1 X$ X$ X$ X$
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
2. Which of the following statements is true regarding planning appointments?
X$ X$ X$ X$ X$ X$ X$ X$ X$
a. Whether or not patients are taking medication for systemic diseases is of littl
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e
consequence in the dental office. X$ X$ X$ X$
b. Asthmatic patients should have dental appointments in the morning. X$ X$ X$ X$ X$ X$ X$ X$
c. Diabetic patients usually have fewer problems with a morning appointment c
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ompared with afternoon appointments. X$ X$ X$
d. Both B and C are true. X$ X$ X$ X$ X$
ANS: D X $
Asthmatic patients who experience dental anxiety should schedule their appointments when they are
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
not rushed or under pressure early in the morning. Diabetic patients usually have relatively fewer pr
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
oblems with a morning appointment. Patients taking medication for systemic diseases may require s
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
pecial handling in the dental office.
X$ X$ X$ X$ X$
DIF: Comprehension
REF: Role of the Dental Hygienist (Appointment Scheduling) | p
X $ X$ X$ X$ X$ X$ X$ X$ X$
. 3 OBJ: 1
X$ X$ TOP: NBDHE, 6.0. Pharmacology
X $ X $ X$ X$
,3. Nutritional or herbal supplements X$ X$ X$
a. carry the U.S. Food and Drug Administration (FDA) approval for disease states
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
.
b. are not drugs. X$ X$
c. can cause adverse effects. X$ X$ X$
d. will not interact with other drugs the patient may be taking.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ANS: C X $
Nutritional or herbal supplements are quite capable of causing adverse effects. The majority of nutritio
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
nal or herbal supplements do not carry FDA approval for treating disease states. These supplements a
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
re drugs and can cause adverse effects and interact with different drugs.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Role of the Dental Hygienist (Nutritional or Herbal Supplements) | p
X $ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
. 3 OBJ: 1
X$ X$ TOP: NBDHE, 6.0. Pharmacology
X $ X $ X$ X$
4. Which type of drug name usually begins with a lowercase letter?
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
a. Brand name X$
b. Code name X$
c. Generic name X$
d. Trade name X$
ANS: C X $
Before any drug is marketed, it is given a generic name that becomes the ―official‖ name of the dru
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
g. Each drug is assigned only one generic name selected by the U.S. Adopted Name Council, and t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
he name is not capitalized. The brand name is equivalent to the trade name and is capitalized. Altho
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ugh the brand name is technically the name of the company marketing the product, this term is often
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
used interchangeably with the trade name. The code name is the initial term used within a pharmac
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
eutical company to refer to a drug while it is undergoing investigation and is often a combination of
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
capital letters and numbers, the letters representing an abbreviation of the company name.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
X $ X$ X$ X$ X$ X$ X $
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
5. A drug’s generic name is selected by the
X$ X$ X$ X$ X$ X$ X$
a. pharmaceutical company manufacturing it. X$ X$ X$
b. Food and Drug Administration (FDA).
X$ X$ X$ X$
c. U.S. Adopted Name Council. X$ X$ X$
d. Federal Patent Office. X$ X$
ANS: C X $
Each drug is assigned only one generic name (e.g., ibuprofen). It is selected by the U.S. Adopted N
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ame Council. The generic name is not selected by the FDA or the Federal Patent Office. The pharm
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
aceutical company manufacturing the drug clearly has an influence on the generic name given its dr
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ug, but the final decision is not the company’s.
X$ X$ X$ X$ X$ X$ X$ X$
DIF: Recall REF: Drug Names | p. 4 X $ X$ X$ X$ X$
OBJ: 3 TOP: NBDHE, 6.0. Pharmacology
X $ X$ X $ X$ X$
6. Which of the following is true concerning generic and trade names of drugs?
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
a. A drug may only have one generic name and one trade nam
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e.
, b. A drug may only have one generic name, but it may have several trade name
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
s.
c. A drug may have several generic names, but it may only have one trade nam
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e.
d. A drug may have several generic names and several trade names.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ANS: B X $
Each drug has only one generic name but may have several trade names. For each drug, there is onl
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
y one generic name. It is not capitalized, and it becomes the ―official‖ name of the drug. The pharm
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
aceutical company discovering the drug gives the drug a trade name. The trade name is protected by
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
the Federal Patent Law for 20 years from the earliest claimed filing date, plus patent term extension
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
s. Although the brand name is technically the name of the company marketing the product, it is ofte
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
n used interchangeably with the trade name.
X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
X $ X$ X$ X$ X$ X$ X $
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
7. Two drugs that are found to be chemically equivalent, but not biologically equivalent o
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
r therapeutically equivalent are said to differ in
X$ X$ X$ X$ X$ X$ X$
a. potency.
b. efficacy.
c. bioavailability.
d. therapeutic index. X$
ANS: C X $
A preparation can be chemically equivalent yet not biologically or therapeutically equivalent. These
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X
products are said to differ in their bioavailability. The potency of a drug is a function of the amount
$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
of drug required to produce an effect. The efficacy is the maximum intensity of effect or response t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
hat can be produced by a drug. The therapeutic index is the ratio of the lethal dose for 50% of the e
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
xperimental animals divided by the effective dose for 50% of the experimental animals. If the value
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
of the therapeutic index is small, toxicity is more likely.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Recall
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
X $ X$ X$ X$ X$ X$ X$ X$ X $ 4
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
8. How many years must pass after a drug patent expires before other drug companies can market t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
he same compound as a generic drug?
X$ X$ X$ X$ X$ X$
a. 20 years X$
b. 17 years X$
c. 7 years X$
d. 0 years X$
ANS: D X $
Once a drug patent expires, competing companies may immediately market the same compound in
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
generic form. The pharmaceutical company discovering the drug gives the drug a trade name. The t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
rade name is protected by the Federal Patent Law for 20 years from the earliest claimed filing date,
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
plus the patent term extensions.
X$ X$ X$ X$
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
X $ X$ X$ X$ X$ X$ X$ X$ X $ 4
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
, 9. Two drug formulations that produce similar concentrations in the blood and tissues after dru
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
g administration are termed
X$ X$ X$ X$ equivalent.
a. chemically
b. biologically
c. therapeutically
ANS: B X $
Biologic equivalence refers to identical pharmacokinetic parameters of two drug formulations (bioe
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
quivalence, for short). Chemical equivalence indicates that two formulations of a drug meet the che
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
mical and physical standards established by the regulatory agencies. Therapeutic equivalence means
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
that two formulations produce the same therapeutic effects over the same duration.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
X $ X$ X$ X$ X$ X$ X$ X$ X $ 4
TOP: NBDHE, 6.0. Pharmacology X $ X$ X$
10. The federal body that determines whether a drug is considered a controlled substance and to whic
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
h schedule it belongs is the
X$ X$ X$ X$ X$
a. Food and Drug Administration (FDA). X$ X$ X$ X$
b. Federal Trade Commission (FTC). X$ X$ X$
c. Drug Enforcement Administration (DEA).X$ X$ X$
d. U.S. Pharmacopeia (USP). X$ X$
ANS: C X $
The DEA regulates the manufacture and distribution of substances with abuse potential. Hence pres
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
criber DEA numbers must appear on prescriptions for controlled substances. The FDA does not hav
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e any special powers in regard to drugs of abuse. The FTC regulates commerce and advertising clai
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ms of foods, over-the-
X$ X$ X$
counter (OTC) products, and cosmetics. The USP regulates the uniformity and purity of drugs.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Federal Regulations and Regulatory Agencies (US Drug Enforcement Administration) | p
X $ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
. 5 OBJ: 5
X$ X$ TOP: NBDHE, 6.0. Pharmacology
X $ X $ X$ X$
11. Which federal regulatory agency decides which drugs require a prescription and which drugs may b
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e sold over-the-counter (OTC)?
X$ X$ X$
a. FDA
b. OSHA
c. FTC
d. DEA
ANS: A X $
The Food and Drug Administration (FDA) is part of Department of Human and Health Services (D
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
HHS), and determines what drugs may be sold by prescription and OTC and regulates the labeling
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
and advertising of prescription drugs. The Occupational Safety and Health Administration (OSHA)
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ensures the safety and health of workers in the United States by setting and enforcing standards. Th
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e Federal Trade Commission (FTC) regulates the trade practices of drug companies and prohibits th
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e false advertising of foods, nonprescription (OTC) drugs, and cosmetics. The Drug Enforcement A
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
dministration (DEA) is a part of the Department of Justice and regulates the manufacture and distri
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
bution of substances that have a potential for abuse, including opioids, stimulants, and sedatives.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
X$ X$ X$ X$ X$ X$ X$ X$
MULTIPLE CHOICE X$
1. Knowledge of pharmacology aids the dental professional in X$ X$ X$ X$ X$ X$ X$
a. obtaining a patient’s health history. X$ X$ X$ X$
b. administering drugs in the office. X$ X$ X$ X$
c. handling emergency situations. X$ X$
d. selection of a nonprescription medication. X$ X$ X$ X$
e. All of the above. X$ X$ X$
ANS: E X $
All of the choices are true. Because many of our patients are being treated with drugs, knowledge o
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
f pharmacology helps in understanding and interpreting patients’ responses to health history question
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
s. Knowledge of the therapeutic and adverse effects of medications obviously helps in their proper a
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
dministration in the office. Emergency situations may be caused by drugs or treated by drugs; thus,
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
knowledge of pharmacology is of great help, especially because a rapid response is sometimes requi
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
red. A clear understanding of the concepts of drug action, drug handling by the body, and drug inter
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
actions will allow the dental practitioner to make proper judgments and grasp the concepts relevant
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
to new drug therapies on the market.
X$ X$ X$ X$ X$ X$
DIF: Application
REF: Role of the Dental Hygienist (Medication/Health History), Role of the Dental Hygienist (Medicati
X $ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
on Administration), Role of the Dental Hygienist (Emergency Situations), Role of the Dental Hygienist (
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
Nonprescription Medication) | pp. 2-3 OBJ: 1 X$ X$ X$ X$
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
2. Which of the following statements is true regarding planning appointments?
X$ X$ X$ X$ X$ X$ X$ X$ X$
a. Whether or not patients are taking medication for systemic diseases is of littl
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e
consequence in the dental office. X$ X$ X$ X$
b. Asthmatic patients should have dental appointments in the morning. X$ X$ X$ X$ X$ X$ X$ X$
c. Diabetic patients usually have fewer problems with a morning appointment c
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ompared with afternoon appointments. X$ X$ X$
d. Both B and C are true. X$ X$ X$ X$ X$
ANS: D X $
Asthmatic patients who experience dental anxiety should schedule their appointments when they are
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
not rushed or under pressure early in the morning. Diabetic patients usually have relatively fewer pr
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
oblems with a morning appointment. Patients taking medication for systemic diseases may require s
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
pecial handling in the dental office.
X$ X$ X$ X$ X$
DIF: Comprehension
REF: Role of the Dental Hygienist (Appointment Scheduling) | p
X $ X$ X$ X$ X$ X$ X$ X$ X$
. 3 OBJ: 1
X$ X$ TOP: NBDHE, 6.0. Pharmacology
X $ X $ X$ X$
,3. Nutritional or herbal supplements X$ X$ X$
a. carry the U.S. Food and Drug Administration (FDA) approval for disease states
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
.
b. are not drugs. X$ X$
c. can cause adverse effects. X$ X$ X$
d. will not interact with other drugs the patient may be taking.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ANS: C X $
Nutritional or herbal supplements are quite capable of causing adverse effects. The majority of nutritio
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
nal or herbal supplements do not carry FDA approval for treating disease states. These supplements a
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
re drugs and can cause adverse effects and interact with different drugs.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Role of the Dental Hygienist (Nutritional or Herbal Supplements) | p
X $ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
. 3 OBJ: 1
X$ X$ TOP: NBDHE, 6.0. Pharmacology
X $ X $ X$ X$
4. Which type of drug name usually begins with a lowercase letter?
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
a. Brand name X$
b. Code name X$
c. Generic name X$
d. Trade name X$
ANS: C X $
Before any drug is marketed, it is given a generic name that becomes the ―official‖ name of the dru
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
g. Each drug is assigned only one generic name selected by the U.S. Adopted Name Council, and t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
he name is not capitalized. The brand name is equivalent to the trade name and is capitalized. Altho
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ugh the brand name is technically the name of the company marketing the product, this term is often
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
used interchangeably with the trade name. The code name is the initial term used within a pharmac
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
eutical company to refer to a drug while it is undergoing investigation and is often a combination of
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
capital letters and numbers, the letters representing an abbreviation of the company name.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
X $ X$ X$ X$ X$ X$ X $
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
5. A drug’s generic name is selected by the
X$ X$ X$ X$ X$ X$ X$
a. pharmaceutical company manufacturing it. X$ X$ X$
b. Food and Drug Administration (FDA).
X$ X$ X$ X$
c. U.S. Adopted Name Council. X$ X$ X$
d. Federal Patent Office. X$ X$
ANS: C X $
Each drug is assigned only one generic name (e.g., ibuprofen). It is selected by the U.S. Adopted N
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ame Council. The generic name is not selected by the FDA or the Federal Patent Office. The pharm
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
aceutical company manufacturing the drug clearly has an influence on the generic name given its dr
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ug, but the final decision is not the company’s.
X$ X$ X$ X$ X$ X$ X$ X$
DIF: Recall REF: Drug Names | p. 4 X $ X$ X$ X$ X$
OBJ: 3 TOP: NBDHE, 6.0. Pharmacology
X $ X$ X $ X$ X$
6. Which of the following is true concerning generic and trade names of drugs?
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
a. A drug may only have one generic name and one trade nam
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e.
, b. A drug may only have one generic name, but it may have several trade name
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
s.
c. A drug may have several generic names, but it may only have one trade nam
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e.
d. A drug may have several generic names and several trade names.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ANS: B X $
Each drug has only one generic name but may have several trade names. For each drug, there is onl
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
y one generic name. It is not capitalized, and it becomes the ―official‖ name of the drug. The pharm
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
aceutical company discovering the drug gives the drug a trade name. The trade name is protected by
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
the Federal Patent Law for 20 years from the earliest claimed filing date, plus patent term extension
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
s. Although the brand name is technically the name of the company marketing the product, it is ofte
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
n used interchangeably with the trade name.
X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
X $ X$ X$ X$ X$ X$ X $
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
7. Two drugs that are found to be chemically equivalent, but not biologically equivalent o
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
r therapeutically equivalent are said to differ in
X$ X$ X$ X$ X$ X$ X$
a. potency.
b. efficacy.
c. bioavailability.
d. therapeutic index. X$
ANS: C X $
A preparation can be chemically equivalent yet not biologically or therapeutically equivalent. These
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X
products are said to differ in their bioavailability. The potency of a drug is a function of the amount
$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
of drug required to produce an effect. The efficacy is the maximum intensity of effect or response t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
hat can be produced by a drug. The therapeutic index is the ratio of the lethal dose for 50% of the e
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
xperimental animals divided by the effective dose for 50% of the experimental animals. If the value
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
of the therapeutic index is small, toxicity is more likely.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Recall
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
X $ X$ X$ X$ X$ X$ X$ X$ X $ 4
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
8. How many years must pass after a drug patent expires before other drug companies can market t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
he same compound as a generic drug?
X$ X$ X$ X$ X$ X$
a. 20 years X$
b. 17 years X$
c. 7 years X$
d. 0 years X$
ANS: D X $
Once a drug patent expires, competing companies may immediately market the same compound in
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
generic form. The pharmaceutical company discovering the drug gives the drug a trade name. The t
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
rade name is protected by the Federal Patent Law for 20 years from the earliest claimed filing date,
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
plus the patent term extensions.
X$ X$ X$ X$
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
X $ X$ X$ X$ X$ X$ X$ X$ X $ 4
TOP: NBDHE, 6.0. Pharmacology
X $ X$ X$
, 9. Two drug formulations that produce similar concentrations in the blood and tissues after dru
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
g administration are termed
X$ X$ X$ X$ equivalent.
a. chemically
b. biologically
c. therapeutically
ANS: B X $
Biologic equivalence refers to identical pharmacokinetic parameters of two drug formulations (bioe
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
quivalence, for short). Chemical equivalence indicates that two formulations of a drug meet the che
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
mical and physical standards established by the regulatory agencies. Therapeutic equivalence means
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
that two formulations produce the same therapeutic effects over the same duration.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
X $ X$ X$ X$ X$ X$ X$ X$ X $ 4
TOP: NBDHE, 6.0. Pharmacology X $ X$ X$
10. The federal body that determines whether a drug is considered a controlled substance and to whic
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
h schedule it belongs is the
X$ X$ X$ X$ X$
a. Food and Drug Administration (FDA). X$ X$ X$ X$
b. Federal Trade Commission (FTC). X$ X$ X$
c. Drug Enforcement Administration (DEA).X$ X$ X$
d. U.S. Pharmacopeia (USP). X$ X$
ANS: C X $
The DEA regulates the manufacture and distribution of substances with abuse potential. Hence pres
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
criber DEA numbers must appear on prescriptions for controlled substances. The FDA does not hav
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e any special powers in regard to drugs of abuse. The FTC regulates commerce and advertising clai
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ms of foods, over-the-
X$ X$ X$
counter (OTC) products, and cosmetics. The USP regulates the uniformity and purity of drugs.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
DIF: Comprehension
REF: Federal Regulations and Regulatory Agencies (US Drug Enforcement Administration) | p
X $ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
. 5 OBJ: 5
X$ X$ TOP: NBDHE, 6.0. Pharmacology
X $ X $ X$ X$
11. Which federal regulatory agency decides which drugs require a prescription and which drugs may b
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e sold over-the-counter (OTC)?
X$ X$ X$
a. FDA
b. OSHA
c. FTC
d. DEA
ANS: A X $
The Food and Drug Administration (FDA) is part of Department of Human and Health Services (D
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
HHS), and determines what drugs may be sold by prescription and OTC and regulates the labeling
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
and advertising of prescription drugs. The Occupational Safety and Health Administration (OSHA)
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
ensures the safety and health of workers in the United States by setting and enforcing standards. Th
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e Federal Trade Commission (FTC) regulates the trade practices of drug companies and prohibits th
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
e false advertising of foods, nonprescription (OTC) drugs, and cosmetics. The Drug Enforcement A
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
dministration (DEA) is a part of the Department of Justice and regulates the manufacture and distri
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
bution of substances that have a potential for abuse, including opioids, stimulants, and sedatives.
X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$ X$
