NURS 5315 UTA Exam 2 Questions and
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what are causes of thrombocytopenia - correct answer -post-op
hemodilution (nadir 2-4 days), splenomegaly, HIV, bone marrow failure,
hemolysis, multiple medications
Primary Immune Thrombocytopenic Purpura- patho and CM - correct
answer -immune mediated destruction of platelets- primary or
secondary (caused by another etiology)
CM- petechiae, purpura, easy bruising, epistaxis, gingival bleeding,
menorrhagia
CM vary with age- worse in elderly
Heparin Induced Thrombocytopenia- patho and CM - correct answer -
immune system destruction of platelets initiated by heparin
Type 1- mild, 2 days post heparin admin, return to normal with
continued administration
Type 2- severe, drug reaction which destroys platelets
,risks- female, heparin use > 1 week, post-op thromboprophylaxis
CM0 unexplained drop in platelets 5-10 days post admin (can be up to 2
weeks post), some will have rapid onset
discuss hemophilia A - correct answer -affects 1 in 5-10K males
sex linked recessive disease, deficient in factor VIII
normal platelets and PT, prolonged PTT, decreased factor VIII
CM: knee, elbow, and ankle bleeds, GI bleeds
discuss hemophilia B - correct answer -affects 1 in 20-30K males
Christmas disease- deficient in factor IX
normal platelets and PT, prolonged PTT, decreased factor IX
CM: knee, elbow, and ankle bleeds, GI bleeds
discuss DIC - correct answer -activation of the coagulation system
causes widespread intravascular fibrin deposition, fibrinolytic products
attempt to break down fibrin- adhere to platelets to prevent adhesion.
coagulation products are eventually consumed and bleeding occurs.
may cause organ failure r/t micro-thrombi
, triggers: malignancy, sepsis, infection, ob complications, trauma, Sx,
ARDS, rhabdo, venomous snake bites
CM: oozing, bleeding from all puncture sites, bleeds from all body
cavities, prolonged PT/PTT, elevated d-dimer, platelet count <100,000
discuss Vitamin K deficiency - correct answer -CM: easy bruising, oozing
from nose or gums, excessive wound bleeding, menorrhagia
discuss liver disease - correct answer -all factors of clotting can be
affected
Hageman deficiency - correct answer -deficiency of factor XII- rare
genetic disorder
asymptomatic, causes prolonged clotting test with no clinical bleeding
or risk present
causes of thrombus - correct answer -Triad of Virchow- injury to blood
vessels, abnormality in blood flow, hypercoagulability
some medications increase risks
Answers 100% Pass |Already Graded
A+| Verified and Updated
what are causes of thrombocytopenia - correct answer -post-op
hemodilution (nadir 2-4 days), splenomegaly, HIV, bone marrow failure,
hemolysis, multiple medications
Primary Immune Thrombocytopenic Purpura- patho and CM - correct
answer -immune mediated destruction of platelets- primary or
secondary (caused by another etiology)
CM- petechiae, purpura, easy bruising, epistaxis, gingival bleeding,
menorrhagia
CM vary with age- worse in elderly
Heparin Induced Thrombocytopenia- patho and CM - correct answer -
immune system destruction of platelets initiated by heparin
Type 1- mild, 2 days post heparin admin, return to normal with
continued administration
Type 2- severe, drug reaction which destroys platelets
,risks- female, heparin use > 1 week, post-op thromboprophylaxis
CM0 unexplained drop in platelets 5-10 days post admin (can be up to 2
weeks post), some will have rapid onset
discuss hemophilia A - correct answer -affects 1 in 5-10K males
sex linked recessive disease, deficient in factor VIII
normal platelets and PT, prolonged PTT, decreased factor VIII
CM: knee, elbow, and ankle bleeds, GI bleeds
discuss hemophilia B - correct answer -affects 1 in 20-30K males
Christmas disease- deficient in factor IX
normal platelets and PT, prolonged PTT, decreased factor IX
CM: knee, elbow, and ankle bleeds, GI bleeds
discuss DIC - correct answer -activation of the coagulation system
causes widespread intravascular fibrin deposition, fibrinolytic products
attempt to break down fibrin- adhere to platelets to prevent adhesion.
coagulation products are eventually consumed and bleeding occurs.
may cause organ failure r/t micro-thrombi
, triggers: malignancy, sepsis, infection, ob complications, trauma, Sx,
ARDS, rhabdo, venomous snake bites
CM: oozing, bleeding from all puncture sites, bleeds from all body
cavities, prolonged PT/PTT, elevated d-dimer, platelet count <100,000
discuss Vitamin K deficiency - correct answer -CM: easy bruising, oozing
from nose or gums, excessive wound bleeding, menorrhagia
discuss liver disease - correct answer -all factors of clotting can be
affected
Hageman deficiency - correct answer -deficiency of factor XII- rare
genetic disorder
asymptomatic, causes prolonged clotting test with no clinical bleeding
or risk present
causes of thrombus - correct answer -Triad of Virchow- injury to blood
vessels, abnormality in blood flow, hypercoagulability
some medications increase risks
