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PMHNP Psychopharmacology Exam 6 Study Guide 2024 | Psychiatric-Mental Health Nurse Practitioner Exam Preparation

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This PMHNP Psychopharmacology Exam 6 Study Guide 2024 (Grade A+) provides a comprehensive set of questions and answers with detailed explanations for students preparing for their Psychopharm Exam 6. Topics include advanced antidepressants, antipsychotics, mood stabilizers, anxiolytics, stimulants, pediatric and geriatric dosing, special populations, drug interactions, side effects, and evidence-based prescribing. Fully verified and updated to 2024 standards, this guide is ideal for PMHNP students at Georgetown University, Yale, University of Pennsylvania, Rush University, and other leading PMHNP programs.

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October 3, 2025
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Written in
2025/2026
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PMHNP Psychopharm Exam 6 2024
NSAIDS - Increases Lithium Levels

Reliability - consistency of measurement
Reliability is another term for consistency. If one person takes the same personality test
several times and always receives the same results, the test is reliable.

internal validity - Refers to how well an experiment is done,
Was it done RIGHT
extent to which we can draw cause-and-effect inferences from a study

Qualitative - Data in the form of recorded descriptions rather than numerical measurements.

Quantitative - relating to, measuring, or measured by the quantity of something rather than its
quality.

Data in numbers

Biggest concern with EMR - Privacy confidentiality

Scope of Practice - STATE

Standards of Practice - ANA

The standard of practice limitations imposed upon a healthcare provider are based on local
regulations and which of the following elements?

Beck Depression - 0-9: indicates minimal depression
10-18: indicates mild depression
19-29: indicates moderate depression
30-63: indicates severe depression.

Hamilton Depression Scale - TOTAL ITEMS 1 TO 17: _______________
0-7=Normal
8 - 13 = Mild Depression
14-18 = Moderate Depression
19 - 22 = Severe Depression
> 23 = Very Severe Depression

PHQ9 - Score Depression severity Comments

0-4 Minimal depression
5-9 Mild depression
10-14 Moderate depression
15-19 Moderate Severe depression
20-27 Severe

,0-4 Minimal or none Monitor; No TX

5-9 Mild Use clinical judgment (symptom duration, functional impairment) to determine
necessity of treatment

10-14 Moderate
15-19 Moderately severe
Warrants active treatment with psychotherapy, medications, or combination

20-27 Severe

Anorexia/Bulimia Admission to Hospital for Pediatrics - American Academy of Pediatrics
Criteria for Inpatient Hospitalization in Eating Disorders
Anorexia nervosa

Heart rate < 50 beats/min daytime; < 45 beats/min nighttime
Systolic blood pressure < 90 mm Hg
Orthostatic changes in pulse (> 20 beats/min) or blood pressure (> 10 mm Hg)
Arrhythmia
Temperature < 96°F
< 75% ideal body weight or ongoing weight loss despite intensive management
Body fat < 10%
Refusal to eat
Failure to respond to outpatient treatment

Bulimia nervosa
Syncope
Serum potassium < 3.2 mmol/L
Serum chloride < 88 mmol/L
Esophageal tears
Cardiac arrhythmias including prolonged QTc
Hypothermia
Suicide risk
Intractable vomiting
Hematemesis
Failure to respond to outpatient treatment

Anorexia Admission -

How long does antidepressants work - 4-6 weeks

Yalom - Yalom's eleven therapeutic factors that influence change and healing in group
therapy:

1. The instillation of hope creates a feeling of optimism.

2. Universality helps group members realize that they are not alone in their impulses,
problems, and other issues.

,3. Imparting information helps to educate and empower people with knowledge pertaining to
their specific psychological situation.

4. Altruism allows clients to gain a sense of value and significance by helping other group
members.

5. Corrective recapitulation provides for the resolution of family and childhood events within
the safety of the group family.

6. Socializing techniques promote social development, tolerance, empathy, and other
interpersonal skills.

7. Through imitative behavior group members learn to adopt the coping strategies and
perspectives of other group members.

8. Interpersonal learning teaches clients how to develop supportive interpersonal
relationships.

9. Group cohesiveness gives members a sense of acceptance, belonging, value, and security.

10. Catharsis releases suppressed emotions and promotes healing by disclosing information to
group members.

11. Existential factors incorporate learning how to just exist as part of something larger than
oneself. This factor brings a client into the awareness that life will continue on, with pain,
death, sadness, regret, and joy. By living existentially, clients learn how to accept these
conditions without escaping from them. Instead, they learn how to live with them and through
them.

Tegretol - Check ANC and WBC- Causes Agranulocytosis

Delirium versus Dementia - Delirium is Acute
Dementia is progressive

Steroids Trigger - Mania

Positive Trendelenburg test - REFER to Ortho

A positive Trendelenburg test usually indicates weakness in the hip abductor muscles: gluteus
medius and gluteus minimus.[1] These findings can be associated with various hip
abnormalities such as congenital hip dislocation, rheumatic arthritis, osteoarthritis.

Tegretol and Erythromycin - Erythromycin inhibitor. You would decrease Tegretol.
Erythromycin would causes toxic Tegretol levels.

CYP Inducers

BULLSHIT CRAP GPS - Decrease other medication
Barbituates
St. Johns Wart

, Carbamazepine
Rifampin
Alcohol
Phentoin
Griseofluvin
Phenobarbital
Sulfonyureas

CYP Inhibitors
SICKFACE.COM - Sodium Valproate
Isoniazid
Cimetidine
Ketoconazole
Fluconazole
Alcohol
Chloramphenicol
Erythromycin
Sulfonamides
Cipro
Omeprazole
Metronidazole

Carb and Barb inducers - Decrease Coumadin

Depakote and Disulfram Inhibitors - Increase Coumadin

Nicotine Inducer-1A - Decreases/metabolizes Zyprexia quicker

GAL (Gabapentin, Acamprosate, Lithium) - Renally Metabolized

STOP SMOKING - Decrease Zyprexia

NSAIDS and ACE inhibitors - Increase Lithium Levels

Nigrostriatal pathways - EPS

Dilated Pupils and Hypertension - Opiate Withdrawal

Behavioral Therapy - For a Child Who Bed Wets

DDVAP - Decreases amount of urine

OTL (Oxazepam, Temazepam, Lorazepam) - Metabolized outside the liver by conjugation.
1/2 lives are the same even with advanced liver disease

Negligence - Autonomy-Independent
Justice -Fair
Beneficence- Do good
Non-maleficence-Do no harm
Validity-Faithful
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