Test bank for Tietz Fundamentals of Clinical Chemistry
bb bb bb bb bb bb bb
bb and Molecular Diagnostics,
bb bb bb
8th Edition by Nader Rifai, PhD
bb bb bb bb bb bb
Chapters 1 - 49 bb bb bb bb
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
bb bb bb bb bb bb bb bb
bb
bb bb
Table of contents:
bb bb
I. Principles Of Laboratory Medicine
bb bb bb bb
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
bb bb bb bb bb bb bb bb
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
bb bb bb bb bb bb bb bb bb bb bb
Chapter 3. Clinical Evaluation of Methods
bb bb bb bb bb
Chapter 4. Evidence-Based Laboratory Medicine
bb bb bb bb
Chapter 5. Establishment and Use of Reference Values
bb bb bb bb bb bb bb
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
bb bb bb bb bb bb bb bb
Chapter 7. Quality Management
bb bb bb
II. Analytical Techniques And Instrumentation
bb bb bb bb
Chapter 8. Principles of Basic Techniques and Laboratory Safety
bb bb bb bb bb bb bb bb
Chapter 9. Optical Techniques
bb bb bb
Chapter 10. Electrochemistry and Chemical Sensors
bb bb bb bb bb
Chapter 11. Electrophoresis
bb bb
Chapter 12. Chromatography
bb bb
Chapter 13. Mass Spectrometry
bb bb bb
Chapter 14. Enzyme and Rate Analyses
bb bb bb bb bb
Chapter 15. Immunochemical Techniques
bb bb bb
Chapter 16 Automation bb bb
Chapter 17. Point-of-Care Instrumentation
bb bb bb
III. Analytes
b b
Chapter 18. Amino Acids, Peptides, and Proteins
bb bb bb bb bb bb
Chapter 19. Serum Enzymes
bb bb bb
Chapter 20. Tumor Markers and Cancer Genes
bb bb bb bb bb bb
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
bb bb bb bb bb bb bb bb bb bb bb
Chapter 22. Carbohydrates
bb bb
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
bb bb bb bb bb bb bb bb bb
Chapter 24. Electrolytes and Blood Gases
bb bb bb bb bb
Chapter 25. Hormones bb bb
Chapter 26. Catecholamines and Serotonin
bb b b bb bb
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
bb b b bb bb bb bb
Chapter 28. Hemoglobin, Iron, and Bilirubin
bb bb bb bb bb
Chapter 29. Porphyrins and Porphyrias
bb bb bb bb
Chapter 30. Therapeutic Drugs and Their Management
bb bb bb bb bb bb
Chapter 31. Clinical Toxicology
bb bb bb
Chapter 32. Toxic Metals
bb b b bb
IV. Pathophysiology
b b
Chapter 33. Diabetes bb bb
,Chapter 34. Cardiovascular Disease
bb b b bb
Chapter 35. Kidney Disease
bb bb bb
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
bb b b bb bb bb bb bb bb bb bb
Chapter 37. Liver Disease
bb bb bb bb
Chapter 38. Gastrointestinal and Pancreatic Diseases
bb b b bb bb bb
Chapter 39. Disorders of Bone and Mineral Metabolism
bb bb bb bb bb bb bb bb
Chapter 40. Disorders of the Pituitary Gland
bb bb bb bb bb bb bb
Chapter 41. Disorders of the Adrenal Cortex
bb b b bb bb bb bb
Chapter 42. Thyroid Disorders
bb b b bb
Chapter 43. Reproduction-Related Disorders
bb b b bb
Chapter 44. Pregnancy and Prenatal Testing
bb bb bb bb bb bb
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
bb b b bb bb bb bb bb bb
Chapter 46. Pharmacogenetics
bb bb
V. Molecular Diagnostics
b b bb
Chapter 47. Principles of Molecular Biology
bb bb bb bb bb
Chapter 48. Nucleic Acid Techniques and Applications
bb bb bb bb bb bb
Chapter 49. Genomes and Nucleic Acid Alterations
bb bb bb bb bb bb
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
bb bb bb bb bb bb bb bb
TestBank
bb b
MULTIPLE CHOICE bb
1. An individual working in a clinical chemistry laboratory is married to a sales
bb bb bb bb bb bb bb bb bb bb bb bb
representative who works for a company that sells chemistry laboratory supplies. When
bb bb bb bb bb bb bb bb bb bb bb bb
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
bb bb bb bb bb bb bb bb bb bb bb bb bb bb
this individual onlyrecommends the spouse’s company as the vendor. This is considered to
bb bb bb b bb bb bb bb bb bb bb bb bb bb
be a(n):
bb bb
a. accounting issue. bb
b. possible conflict of interest. bb bb bb
c. maintenance of confidentiality issue. bb bb bb
d. problem with resource allocation. bb bb bb
ANS: B bb
Concern has been raised over the interrelationships between practitioners in the medical
bb bb bb bb bb bb bb bb bb bb bb
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
bb b bb bb bb bb bb bb bb bb bb bb
profession.
bb
Similarly, relationships have been scrutinized between clinical laboratorians and
bb bb bb bb bb bb bb bb
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
bb bb bb bb bb bb bb bb bb bb bb bb
National Institutes of Health (NIH) in 1995 to require official institutional review of
bb bb bb bb bb bb bb bb bb bb bb bb bb
financial disclosure by researchers and management of situations in which disclosure
bb bb bb bb bb bb bb bb bb bb bb
indicates potentialconflicts of interest.
bb bb b bb bb
DIF: 1 REF: bb bb bb Page 4-5 bb OBJ: 6 | 7 bb bb bb
2. A patient visits her physician stating that her prescribed painkiller is not working to
bb bb bb bb bb bb bb bb bb bb bb bb bb
reduce the pain following her recent surgery. A friend of the patient claims that the same
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
painkiller―worked wonders‖ to reduce her pain after the same surgery. The physician
bb b bb bb bb bb bb bb bb bb bb bb bb
states that the difference in the effect of the drug might be caused by , which is studied
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
in pharmacogenetics.
bb bb
a. epidemiology
b. an inherited disease bb bb
c. a conflict of interest
bb bb bb
d. a genetic variation in drug-metabolizing enzymes
bb bb bb bb bb
ANS: D bb
Pharmacogenetics is the study of the genetic variation of drug metabolism bb bb bb bb bb bb bb bb bb bb
betweenindividuals.
bb b
DIF: 1 REF: bb bb b b Page 3 bb OBJ: 1 bb
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
bb bb bb bb bb bb bb bb bb bb bb bb bb
the name of a close friend printed on the bar-coded label. The genetic test that is ordered
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
on thefriend’s sample would provide diagnostic information about a disorder that has a
bb bb b bb bb bb bb bb bb bb bb bb bb bb
poor prognosis, and the test is usually performed by John. He asks a fellow employee to
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
analyzethe sample for him and not divulge the results. This ethical issue concerns:
bb b bb bb bb bb bb bb bb bb bb bb bb bb
a. confidentiality of patient genetic and medical information. bb bb bb bb bb bb
b. a conflict of interest.
bb bb bb
c. resource allocation. bb
d. diagnostic accuracy. bb
bb bb bb bb bb bb bb
bb and Molecular Diagnostics,
bb bb bb
8th Edition by Nader Rifai, PhD
bb bb bb bb bb bb
Chapters 1 - 49 bb bb bb bb
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
bb bb bb bb bb bb bb bb
bb
bb bb
Table of contents:
bb bb
I. Principles Of Laboratory Medicine
bb bb bb bb
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
bb bb bb bb bb bb bb bb
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
bb bb bb bb bb bb bb bb bb bb bb
Chapter 3. Clinical Evaluation of Methods
bb bb bb bb bb
Chapter 4. Evidence-Based Laboratory Medicine
bb bb bb bb
Chapter 5. Establishment and Use of Reference Values
bb bb bb bb bb bb bb
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
bb bb bb bb bb bb bb bb
Chapter 7. Quality Management
bb bb bb
II. Analytical Techniques And Instrumentation
bb bb bb bb
Chapter 8. Principles of Basic Techniques and Laboratory Safety
bb bb bb bb bb bb bb bb
Chapter 9. Optical Techniques
bb bb bb
Chapter 10. Electrochemistry and Chemical Sensors
bb bb bb bb bb
Chapter 11. Electrophoresis
bb bb
Chapter 12. Chromatography
bb bb
Chapter 13. Mass Spectrometry
bb bb bb
Chapter 14. Enzyme and Rate Analyses
bb bb bb bb bb
Chapter 15. Immunochemical Techniques
bb bb bb
Chapter 16 Automation bb bb
Chapter 17. Point-of-Care Instrumentation
bb bb bb
III. Analytes
b b
Chapter 18. Amino Acids, Peptides, and Proteins
bb bb bb bb bb bb
Chapter 19. Serum Enzymes
bb bb bb
Chapter 20. Tumor Markers and Cancer Genes
bb bb bb bb bb bb
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
bb bb bb bb bb bb bb bb bb bb bb
Chapter 22. Carbohydrates
bb bb
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
bb bb bb bb bb bb bb bb bb
Chapter 24. Electrolytes and Blood Gases
bb bb bb bb bb
Chapter 25. Hormones bb bb
Chapter 26. Catecholamines and Serotonin
bb b b bb bb
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
bb b b bb bb bb bb
Chapter 28. Hemoglobin, Iron, and Bilirubin
bb bb bb bb bb
Chapter 29. Porphyrins and Porphyrias
bb bb bb bb
Chapter 30. Therapeutic Drugs and Their Management
bb bb bb bb bb bb
Chapter 31. Clinical Toxicology
bb bb bb
Chapter 32. Toxic Metals
bb b b bb
IV. Pathophysiology
b b
Chapter 33. Diabetes bb bb
,Chapter 34. Cardiovascular Disease
bb b b bb
Chapter 35. Kidney Disease
bb bb bb
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
bb b b bb bb bb bb bb bb bb bb
Chapter 37. Liver Disease
bb bb bb bb
Chapter 38. Gastrointestinal and Pancreatic Diseases
bb b b bb bb bb
Chapter 39. Disorders of Bone and Mineral Metabolism
bb bb bb bb bb bb bb bb
Chapter 40. Disorders of the Pituitary Gland
bb bb bb bb bb bb bb
Chapter 41. Disorders of the Adrenal Cortex
bb b b bb bb bb bb
Chapter 42. Thyroid Disorders
bb b b bb
Chapter 43. Reproduction-Related Disorders
bb b b bb
Chapter 44. Pregnancy and Prenatal Testing
bb bb bb bb bb bb
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
bb b b bb bb bb bb bb bb
Chapter 46. Pharmacogenetics
bb bb
V. Molecular Diagnostics
b b bb
Chapter 47. Principles of Molecular Biology
bb bb bb bb bb
Chapter 48. Nucleic Acid Techniques and Applications
bb bb bb bb bb bb
Chapter 49. Genomes and Nucleic Acid Alterations
bb bb bb bb bb bb
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
bb bb bb bb bb bb bb bb
TestBank
bb b
MULTIPLE CHOICE bb
1. An individual working in a clinical chemistry laboratory is married to a sales
bb bb bb bb bb bb bb bb bb bb bb bb
representative who works for a company that sells chemistry laboratory supplies. When
bb bb bb bb bb bb bb bb bb bb bb bb
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
bb bb bb bb bb bb bb bb bb bb bb bb bb bb
this individual onlyrecommends the spouse’s company as the vendor. This is considered to
bb bb bb b bb bb bb bb bb bb bb bb bb bb
be a(n):
bb bb
a. accounting issue. bb
b. possible conflict of interest. bb bb bb
c. maintenance of confidentiality issue. bb bb bb
d. problem with resource allocation. bb bb bb
ANS: B bb
Concern has been raised over the interrelationships between practitioners in the medical
bb bb bb bb bb bb bb bb bb bb bb
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
bb b bb bb bb bb bb bb bb bb bb bb
profession.
bb
Similarly, relationships have been scrutinized between clinical laboratorians and
bb bb bb bb bb bb bb bb
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
bb bb bb bb bb bb bb bb bb bb bb bb
National Institutes of Health (NIH) in 1995 to require official institutional review of
bb bb bb bb bb bb bb bb bb bb bb bb bb
financial disclosure by researchers and management of situations in which disclosure
bb bb bb bb bb bb bb bb bb bb bb
indicates potentialconflicts of interest.
bb bb b bb bb
DIF: 1 REF: bb bb bb Page 4-5 bb OBJ: 6 | 7 bb bb bb
2. A patient visits her physician stating that her prescribed painkiller is not working to
bb bb bb bb bb bb bb bb bb bb bb bb bb
reduce the pain following her recent surgery. A friend of the patient claims that the same
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
painkiller―worked wonders‖ to reduce her pain after the same surgery. The physician
bb b bb bb bb bb bb bb bb bb bb bb bb
states that the difference in the effect of the drug might be caused by , which is studied
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
in pharmacogenetics.
bb bb
a. epidemiology
b. an inherited disease bb bb
c. a conflict of interest
bb bb bb
d. a genetic variation in drug-metabolizing enzymes
bb bb bb bb bb
ANS: D bb
Pharmacogenetics is the study of the genetic variation of drug metabolism bb bb bb bb bb bb bb bb bb bb
betweenindividuals.
bb b
DIF: 1 REF: bb bb b b Page 3 bb OBJ: 1 bb
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
bb bb bb bb bb bb bb bb bb bb bb bb bb
the name of a close friend printed on the bar-coded label. The genetic test that is ordered
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
on thefriend’s sample would provide diagnostic information about a disorder that has a
bb bb b bb bb bb bb bb bb bb bb bb bb bb
poor prognosis, and the test is usually performed by John. He asks a fellow employee to
bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb bb
analyzethe sample for him and not divulge the results. This ethical issue concerns:
bb b bb bb bb bb bb bb bb bb bb bb bb bb
a. confidentiality of patient genetic and medical information. bb bb bb bb bb bb
b. a conflict of interest.
bb bb bb
c. resource allocation. bb
d. diagnostic accuracy. bb
