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, Berne and Levy Physiology 7th Edition Koeppen
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Berne and Levy Physiology 7th Edition KoeppenTest Bank
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Koeppen: Berne and Levy Physiology, 7th Edition hj hj hj hj hj hj
Chapter 01: Principles of Cell hj hj hj hj
FunctionTest Bank hj
Multiple Choice hj
1. The subcellular structure that degrades proteins is called the:
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A. Tight junction hj
B. Mitochondria
C. Lysosome
D. Plasma membrane hj
E. Ribosome
ANS: C h j
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
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data are obtained: hj hj
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the c
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ell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is marke
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dly reduced. According to this information, which of the followingmechanisms is probably res
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ponsible for the transport of the amino acid into the cell?
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A. Passive diffusion through the lipid bilayer hj hj hj hj hj
B. Uniporter
C. Transport ATPase hj
D. Na+ symporter hj
E. Na+ antiporterhj h
ANS: D
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3. A membrane permeable by only Na+ separates two compartments containing
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Na2SO4,shown as follows: hj hj
, Berne and Levy Physiology 7th Edition Koeppen
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Electrodes are placed in both compartments, and a voltage is applied (that of compartment A is
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held at 0 mV). What voltage applied to compartment B would resultin no net movement of Na+
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across the membrane separating the compartments?
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A. –60 mV hj
B. –30 mV hj
C. 0 mV hj
D. +30 mV hj
E.
+60 mV hj
hj ANS: E h j
4. The resting membrane potentN
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B85.m U S N concentrations of several ions are indicated in
CV. The intracellular and extracellular hj hj hj hj
hj hj
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the following table, as is the calculated
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Nernst equilibrium potential (Ei) for each of these ions:
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Ion Concentration Concentration Ei
Inside Cell hj Outside Cell hj
+
Na 12 mEq/L hj 145 mEq/L hj 66 mV hj
K+ 150 mEq/L hj 4 mEq/L
hj –96 mV hj
Cl– 30 mEq/L hj 105 mEq/L hj –33 mV hj
Ca++ 0.0001 mmol/dL hj 1 mmol/dL
hj 122 mV hj
The membrane has channels for Na+, K+, Cl–
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, and Ca++. The conductance of the membrane is the greatest for which ion?
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A. Na+
B. K+
Cl– C.
D. Ca++ A h j
NS: B hj
5. A cell contains the following membrane transporters:
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Na+ channelK+ channel
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Na+,K+-ATPase
, Berne and Levy Physiology 7th Edition Koeppen
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The resting membrane voltage of the cell is –80 mV, and the intracellular and
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extracellular ion concentrations are as follows:
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Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L hj 145 mEq/L hj
K+ 120 mEq/L hj 4 mEq/L hj
The cell is treated with a drug to inhibit the Na+,K+-
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ATPase. What would be the effect ofthis drug on the following parameters?
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Intracellular [Na+] hj Intracellular [K+] hj Cell Volume
hj Membrane Voltage hj
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
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D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B h j
6. Which of the labeled proteins (shaded) is attached to the membrane by a
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glycosylphosphatidylinositol (GPI) anchor? hj hj
ANS: E h j
7. A cell has channels for Na+, K+, and Cl–
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in its plasma membrane. The resting membrane potential is –
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60 mV (cell interior negative). The intracellular and extracellular concentrations for
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these ions, as well as the calculated Nernst potentials, are listed as follows:
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