AAMI GEN 311 Intro to Pathology Comp
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Degeneration - ANS regressive tissue change characterized by swelling of cells and chemical
changes within the cells cytoplasm
changes due to degeneration leads to - ANS the appearance w/in the cell of substances
normally absent or normally present in very small to undetectable amounts
form of degeneration cloudy swelling - ANS most common and least damaging type of
degeneration
cloudy swelling is seen in most - ANS infections
burn
malnutrition
shock
cloudy swelling involves organs - ANS liver
kidneys
cloudy swelling does not often effect the - ANS heart
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with cloudy swelling the - ANS cells appear swollen
opaque
cloudy
fatty degeneration or steatosis - ANS abnormal accumulation of fat or lipid w/in the cell
most common organ affected by fatty degeneration or steatosis - ANS liver
alcoholism is the most common form of - ANS etiology (cause of fatty
degeneration/steatosis)
other common causes for fatty degeneration or steatosis - ANS starvation
heavy metal poisoning
chronic passive congestion
prolonged fevers
anoxia (lack of sufficient oxygen for normal function)
anoxia - ANS lack of sufficient oxygen for normal function
grossly fatty liver is - ANS yellow
soft
greasy
with a fatty liver the microscope shows - ANS individual cells with the normally pink
cytoplasm all buy cleared out by fat giving the cells and empty appearance
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fatty degeneration or steatosis change is potentially - ANS reversible but may progress to
scarring and cirrhosis if the source of damage is not addressed
amyloid disease - ANS waxy starch like
amyloid disease is a disease - ANS which a waxy starch like glycoprotein accumulates in
tissues and organs impairing their function
amyloid is formed - ANS in the body and deposited in various organs
deposition of waxy starch like substance can be - ANS wide spread
depending on the specific disease process and involve the kidney
liver
spleen
adrenal glands
other organs
the accumulation of amyloid may - ANS represent a primary disease (amyloidosis)
infiltration - ANS process of a substance passing into a cell and being deposited w/in the
substance of a cell, tissue or organ
infiltration is an accumulation - ANS of a substance that is not normally present or is present
in an excess amount
infiltration is - ANS an intracellular change
pigmentation - ANS increasse in the amount or irregular distribution or pigments (color)
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two types of pigmentation - ANS exogenous pigmentation
endogenous pigmentation
exogenous pigmentation - ANS tissue discoloration due to pigments that are not normally
present in the body
exogenous pigmentation come from - ANS outside the body such as breathing
(pneumoconiosis)
example of exogenous pigmentation - ANS carotenemia
anthracosis
carotenemia - ANS yellow discoloration of the skin from eating large amounts of carotene
containing food such as carrots
carotenemia is often confused with - ANS jaundice
jaundice - ANS endogenous pigmentation
anthroacosis - ANS a carbon pigmentation deposited in the lungs when inhaling coal dust
over a long period of time
endogenous pigmentation - ANS tissue discoloration due to pigment that are normally
present in the body
example of endogenous pigmentation - ANS melanin
freckles