Test bank for Tietz Fundamentals of Clinical Chemistry
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and Molecular Diagnostics 8th Edition
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cc by Nader Rifai, PhD Chapters 1 - 49
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Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents: cc cc
I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatographycc cc
Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation cc cc
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes cc cc cc
Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates cc cc
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones cc cc
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals cc c c cc
IV. Pathophysiology
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Chapter 33. Diabetes cc cc
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, TO GET ALL CHAPTERS EMAIL ME AT>>>>>
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cc
TO GET ALL CHAPTERS EMAIL ME AT>>>>>
cc cc cc cc cc cc cc cc cc
cc
Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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cTestBank
c
MULTIPLE CHOICE cc
1. An individual working in a clinical chemistry laboratory is married to a sales representative
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c who works for a company that sells chemistry laboratory supplies. When the laboratory
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c manager requests a list of needed supplies, cost of supplies, and vendors, this individual only
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recommends the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. cc
b. possible conflict of interest. cc cc cc
c. maintenance of confidentiality issue. cc cc cc
d. problem with resource allocation. cc cc cc
ANS: B cc
Concern has been raised over the interrelationships between practitioners in the medical field
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c and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
c cc cc cc cc cc cc cc cc cc cc cc
Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
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and providers of diagnostic equipment and supplies. These concerns led the National
cc cc cc cc cc cc cc cc cc cc cc c c
Institutes of Health (NIH) in 1995 to require official institutional review of financial disclosure
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by researchers and management of situations in which disclosure indicates potential conflicts of
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interest.
cc
DIF: 1 REF: Page 4-5 cc cc cc cc OBJ: 6 | 7 cc cc cc
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce
cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c the pain following her recent surgery. A friend of the patient claims that the same painkiller
c cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c ―worked wonders‖ to reduce her pain after the same surgery. The physician states that the
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c difference in the effect of the drug might be caused by
c , which is studied in
cc cc cc cc cc cc cc cc cc cc cc cc cc cc
pharmacogenetics.
c c
a. epidemiology
b. an inherited disease cc cc
c. a conflict of interest cc cc cc
d. a genetic variation in drug-metabolizing enzymes
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ANS: D cc
Pharmacogenetics is the study of the genetic variation of drug metabolism between cc cc cc cc cc cc cc cc cc cc cc
cindividuals.
c
DIF: 1 REF: Page 3 cc cc c c cc OBJ: 1 cc
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the
cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c c name of a close friend printed on the bar-coded label. The genetic test that is ordered on the
cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c c friend’s sample would provide diagnostic information about a disorder that has a poor
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c c prognosis, and the test is usually performed by John. He asks a fellow employee to analyze
cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c c the sample for him and not divulge the results. This ethical issue concerns:
cc cc cc cc cc cc cc cc cc cc cc cc
cc cc cc cc cc cc cc
and Molecular Diagnostics 8th Edition
cc cc cc c c
cc by Nader Rifai, PhD Chapters 1 - 49
cc cc cc c c cc cc cc
,cc
Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
cc cc cc cc cc cc cc cc
cc
cc cc
Table of contents: cc cc
I. Principles Of Laboratory Medicine
cc cc cc cc
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
cc cc cc cc cc cc cc cc
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
cc cc cc cc cc cc cc cc cc cc cc
Chapter 3. Clinical Evaluation of Methods
cc cc cc cc cc
Chapter 4. Evidence-Based Laboratory Medicine
cc cc cc cc
Chapter 5. Establishment and Use of Reference Values
cc cc cc cc cc cc cc
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
cc cc cc cc cc cc cc cc
Chapter 7. Quality Management
cc cc cc
II. Analytical Techniques And Instrumentation
cc cc cc cc
Chapter 8. Principles of Basic Techniques and Laboratory Safety
cc cc cc cc cc cc cc cc
Chapter 9. Optical Techniques
cc cc cc
Chapter 10. Electrochemistry and Chemical Sensors
cc cc cc cc cc
Chapter 11. Electrophoresis
cc cc
Chapter 12. Chromatographycc cc
Chapter 13. Mass Spectrometry
cc cc cc
Chapter 14. Enzyme and Rate Analyses
cc cc cc cc cc
Chapter 15. Immunochemical Techniques
cc cc cc
Chapter 16 Automation cc cc
Chapter 17. Point-of-Care Instrumentation
cc cc cc
III. Analytes
cc cc
Chapter 18. Amino Acids, Peptides, and Proteins
cc cc cc cc cc cc
Chapter 19. Serum Enzymes cc cc cc
Chapter 20. Tumor Markers and Cancer Genes
cc cc cc cc cc cc
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
cc cc cc cc cc cc cc cc cc cc cc
Chapter 22. Carbohydrates cc cc
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
cc cc cc cc cc cc cc cc cc
Chapter 24. Electrolytes and Blood Gases
cc cc cc cc cc
Chapter 25. Hormones cc cc
Chapter 26. Catecholamines and Serotonin
cc c c cc cc
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
cc cc cc cc cc cc cc
Chapter 28. Hemoglobin, Iron, and Bilirubin
cc cc cc cc cc
Chapter 29. Porphyrins and Porphyrias
cc cc cc cc
Chapter 30. Therapeutic Drugs and Their Management
cc cc cc cc cc cc
Chapter 31. Clinical Toxicology
cc cc cc
Chapter 32. Toxic Metals cc c c cc
IV. Pathophysiology
cc cc
Chapter 33. Diabetes cc cc
,Chapter 34. Cardiovascular Disease
cc c c cc
Chapter 35. Kidney Disease
cc cc cc
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
cc c c cc cc cc cc cc cc cc cc
Chapter 37. Liver Disease
cc cc cc cc
Chapter 38. Gastrointestinal and Pancreatic Diseases
cc c c cc cc cc
Chapter 39. Disorders of Bone and Mineral Metabolism
cc cc cc cc cc cc cc cc
Chapter 40. Disorders of the Pituitary Gland
cc cc cc cc cc cc cc
Chapter 41. Disorders of the Adrenal Cortex
cc c c cc cc cc cc
Chapter 42. Thyroid Disorders
cc c c cc
Chapter 43. Reproduction-Related Disorders
cc c c cc
Chapter 44. Pregnancy and Prenatal Testing
cc cc cc cc cc cc
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
cc c c cc cc cc cc cc cc
Chapter 46. Pharmacogenetics
cc cc
V. Molecular Diagnostics
cc cc cc
Chapter 47. Principles of Molecular Biology
cc cc cc cc cc
Chapter 48. Nucleic Acid Techniques and Applications
cc cc cc cc cc cc
Chapter 49. Genomes and Nucleic Acid Alterations
cc cc cc cc cc cc
, TO GET ALL CHAPTERS EMAIL ME AT>>>>>
cc cc cc cc cc cc cc cc cc
cc
TO GET ALL CHAPTERS EMAIL ME AT>>>>>
cc cc cc cc cc cc cc cc cc
cc
Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
cc cc cc cc cc cc cc cc
cTestBank
c
MULTIPLE CHOICE cc
1. An individual working in a clinical chemistry laboratory is married to a sales representative
cc cc cc cc cc cc cc cc cc cc cc cc cc
c who works for a company that sells chemistry laboratory supplies. When the laboratory
c cc cc cc cc cc cc cc cc cc cc cc cc
c manager requests a list of needed supplies, cost of supplies, and vendors, this individual only
c cc cc cc cc cc cc cc cc cc cc cc cc cc cc
recommends the spouse’s company as the vendor. This is considered to be a(n):
c c cc cc cc cc cc cc cc cc cc cc cc cc
a. accounting issue. cc
b. possible conflict of interest. cc cc cc
c. maintenance of confidentiality issue. cc cc cc
d. problem with resource allocation. cc cc cc
ANS: B cc
Concern has been raised over the interrelationships between practitioners in the medical field
cc cc cc cc cc cc cc cc cc cc cc cc
c and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
c cc cc cc cc cc cc cc cc cc cc cc
Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
cc cc cc cc cc cc cc cc c c
and providers of diagnostic equipment and supplies. These concerns led the National
cc cc cc cc cc cc cc cc cc cc cc c c
Institutes of Health (NIH) in 1995 to require official institutional review of financial disclosure
cc cc cc cc cc cc cc cc cc cc cc cc cc c c
by researchers and management of situations in which disclosure indicates potential conflicts of
cc cc cc cc cc cc cc cc cc cc cc c c cc
interest.
cc
DIF: 1 REF: Page 4-5 cc cc cc cc OBJ: 6 | 7 cc cc cc
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce
cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c the pain following her recent surgery. A friend of the patient claims that the same painkiller
c cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c ―worked wonders‖ to reduce her pain after the same surgery. The physician states that the
c cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c difference in the effect of the drug might be caused by
c , which is studied in
cc cc cc cc cc cc cc cc cc cc cc cc cc cc
pharmacogenetics.
c c
a. epidemiology
b. an inherited disease cc cc
c. a conflict of interest cc cc cc
d. a genetic variation in drug-metabolizing enzymes
cc cc cc cc cc
ANS: D cc
Pharmacogenetics is the study of the genetic variation of drug metabolism between cc cc cc cc cc cc cc cc cc cc cc
cindividuals.
c
DIF: 1 REF: Page 3 cc cc c c cc OBJ: 1 cc
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the
cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c c name of a close friend printed on the bar-coded label. The genetic test that is ordered on the
cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c c friend’s sample would provide diagnostic information about a disorder that has a poor
cc cc cc cc cc cc cc cc cc cc cc cc
c c prognosis, and the test is usually performed by John. He asks a fellow employee to analyze
cc cc cc cc cc cc cc cc cc cc cc cc cc cc cc
c c the sample for him and not divulge the results. This ethical issue concerns:
cc cc cc cc cc cc cc cc cc cc cc cc
