ATI Pharmacology Made Easy 5.0: The
Gastrointestinal System Test Questions
and Answers | Latest Version | 2025/2026
| Correct & Verified
What is the primary role of proton pump inhibitors (PPIs) in managing gastrointestinal
conditions?
✔✔PPIs reduce gastric acid production, helping to treat conditions like GERD, ulcers, and
Zollinger-Ellison syndrome.
What should a nurse monitor when administering a laxative to a patient?
✔✔The nurse should monitor the patient for signs of dehydration, electrolyte imbalances, and
the frequency of bowel movements.
How does an H2 receptor antagonist work to reduce acid production?
✔✔H2 receptor antagonists block histamine receptors in the stomach, reducing gastric acid
secretion and helping to treat ulcers and GERD.
What is a common side effect of antacids that a nurse should be aware of?
1
, ✔✔Constipation or diarrhea can occur, depending on the type of antacid (e.g., aluminum-based
antacids may cause constipation).
Why is it important to educate a patient about the timing of taking antacids in relation to meals?
✔✔Antacids should be taken either one hour after meals or at bedtime to ensure they provide the
most effective relief by neutralizing stomach acid after food is digested.
What is the primary action of antiemetic drugs like ondansetron in patients with nausea and
vomiting?
✔✔Antiemetics block serotonin receptors in the gastrointestinal tract and central nervous
system, reducing nausea and vomiting.
What is a significant concern when a patient is prescribed a drug like sucralfate for an ulcer?
✔✔Sucralfate can interfere with the absorption of other medications, so it should be taken at
least 2 hours apart from other drugs.
What is the purpose of administering a prokinetic agent like metoclopramide?
✔✔Prokinetic agents help increase gastric motility and are used to treat conditions like
gastroparesis or severe GERD.
2
Gastrointestinal System Test Questions
and Answers | Latest Version | 2025/2026
| Correct & Verified
What is the primary role of proton pump inhibitors (PPIs) in managing gastrointestinal
conditions?
✔✔PPIs reduce gastric acid production, helping to treat conditions like GERD, ulcers, and
Zollinger-Ellison syndrome.
What should a nurse monitor when administering a laxative to a patient?
✔✔The nurse should monitor the patient for signs of dehydration, electrolyte imbalances, and
the frequency of bowel movements.
How does an H2 receptor antagonist work to reduce acid production?
✔✔H2 receptor antagonists block histamine receptors in the stomach, reducing gastric acid
secretion and helping to treat ulcers and GERD.
What is a common side effect of antacids that a nurse should be aware of?
1
, ✔✔Constipation or diarrhea can occur, depending on the type of antacid (e.g., aluminum-based
antacids may cause constipation).
Why is it important to educate a patient about the timing of taking antacids in relation to meals?
✔✔Antacids should be taken either one hour after meals or at bedtime to ensure they provide the
most effective relief by neutralizing stomach acid after food is digested.
What is the primary action of antiemetic drugs like ondansetron in patients with nausea and
vomiting?
✔✔Antiemetics block serotonin receptors in the gastrointestinal tract and central nervous
system, reducing nausea and vomiting.
What is a significant concern when a patient is prescribed a drug like sucralfate for an ulcer?
✔✔Sucralfate can interfere with the absorption of other medications, so it should be taken at
least 2 hours apart from other drugs.
What is the purpose of administering a prokinetic agent like metoclopramide?
✔✔Prokinetic agents help increase gastric motility and are used to treat conditions like
gastroparesis or severe GERD.
2
