4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
NBME CBSE (usmle step 1) MEDICAL ACTUAL EXAM NEWEST
VERSION 2024-2025 TESTBANK QUESTIONS
AND CORRECT DETAILEDANSWERS WITH RATIONALES
|ALREADY GRADED A+
Terms in this set (1957)
70yo M dies in a motor Tubular adenoma
vehicle collision. Was
undergoing evaluation for
occult blood in the stool.
Photo of transverse colon
shown. Dx?
38yo M with 1-week hx of Loratadine
watery, itchy eyes and a
runny nose. Physical shows
inflamed nasal mucosa. No
congestion in lower lung.
Pharmacotherapy?
16yo girl with 3-day hx of IgM
fever, nonproductive cough,
and fatigue. T 38.3, P
88/min, BP 102-70. PE
shows pale conjunctivae.
CXR shows bilateral
interstitial infiltrates. Blood
spontaenously agglutinates
while awaiting transport to
the laboratory. Antibody
isotypes causing
agglutination?
24yo M with small tender HSV-2
blisters on his penis 3 days
after unprotected sex.
Photograph shown. Causal
agent?
… 1/281
,4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
42yo F with 3-year hx of Rosacea
an intermittent facial rash,
including the forehead,
eyelids, nose, and cheeks.
Rash seems to be getting
worse since she moved
from New York to Florida
last year. Spicy foods
precipitate a flushing
reaction that seems to
exacerbate the rash. PE
shows erythema over the
nose and cheeks, with
scattered telangiectasias
and a few papules. Dx?
53yo M returned from Malaria
Africa, has fever,
headache, and abdominal
discomfort. Received
appropriate vaccinations
prior to the trip. T 39.4C. A
wright-stained peripheral
smear shown. Dx?
68yo F with T2DM and Lisinopril
hypertension that has
been poorly controlled
despite hydrochlorothiazide
treatment. BP 150/96, Labs
show serum glucose
concentration of 130 and
proteinuria. In addition to
current Rx, which is most
appropriate
pharmacotherapy?
… 2/281
,4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
66yo M with stage IV colon Loperamide
cancer with 3- day hx of
severe diarrhea after
receiving chemotherapy
with fluorouracil, leucovorin,
and Irinotecan. prescribed
opioid antidiarrheal agent
with no CNS effects.
Which med?
35yo M in ED with 2-hour Activation of adenylyl cyclase
hx of sever fatigue and
dizziness. Had profuse,
watery diarrhea for 8 hours
despite a lack of oral
intake. Recently returned
from a medical relief trip to
a remove village in
Honduras. T
36.7 C, P 122/min, BP
90/50. PE shows dry skin
and decreased capillary
refill. Stool for occult blood
is negative; stool is gray
and turbid. Gram stain
shows gram-negative,
comma-shaped bacteria;
no erythrocytes of
leukocytes. MOA of toxin?
59yo F with gradual onset of cerebellum
lack of muscle control in her
left arm and leg. Sx 1 mo
ago after dx with
metastatic breast cancer.
PE shows ataxia of left
upper and lower
extremities. Muscle
strength, DTR, sensation,
proprioception normal.
… 3/281
, 4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
Metastatic tumor in which
location?
Newborn delivered at 38 Congenital cytomegalovirus infection
weeks' gestation weighs
1800 g. PE shows petechial
rash, microcephaly, and
hepatosplenomegaly.
Serologic test for CMV: IgG +
in mother, + in newborn;
IGM - in mother, + in
newborn.
Explanation?
… 4/281
NBME CBSE (usmle step 1) MEDICAL ACTUAL EXAM NEWEST
VERSION 2024-2025 TESTBANK QUESTIONS
AND CORRECT DETAILEDANSWERS WITH RATIONALES
|ALREADY GRADED A+
Terms in this set (1957)
70yo M dies in a motor Tubular adenoma
vehicle collision. Was
undergoing evaluation for
occult blood in the stool.
Photo of transverse colon
shown. Dx?
38yo M with 1-week hx of Loratadine
watery, itchy eyes and a
runny nose. Physical shows
inflamed nasal mucosa. No
congestion in lower lung.
Pharmacotherapy?
16yo girl with 3-day hx of IgM
fever, nonproductive cough,
and fatigue. T 38.3, P
88/min, BP 102-70. PE
shows pale conjunctivae.
CXR shows bilateral
interstitial infiltrates. Blood
spontaenously agglutinates
while awaiting transport to
the laboratory. Antibody
isotypes causing
agglutination?
24yo M with small tender HSV-2
blisters on his penis 3 days
after unprotected sex.
Photograph shown. Causal
agent?
… 1/281
,4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
42yo F with 3-year hx of Rosacea
an intermittent facial rash,
including the forehead,
eyelids, nose, and cheeks.
Rash seems to be getting
worse since she moved
from New York to Florida
last year. Spicy foods
precipitate a flushing
reaction that seems to
exacerbate the rash. PE
shows erythema over the
nose and cheeks, with
scattered telangiectasias
and a few papules. Dx?
53yo M returned from Malaria
Africa, has fever,
headache, and abdominal
discomfort. Received
appropriate vaccinations
prior to the trip. T 39.4C. A
wright-stained peripheral
smear shown. Dx?
68yo F with T2DM and Lisinopril
hypertension that has
been poorly controlled
despite hydrochlorothiazide
treatment. BP 150/96, Labs
show serum glucose
concentration of 130 and
proteinuria. In addition to
current Rx, which is most
appropriate
pharmacotherapy?
… 2/281
,4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
66yo M with stage IV colon Loperamide
cancer with 3- day hx of
severe diarrhea after
receiving chemotherapy
with fluorouracil, leucovorin,
and Irinotecan. prescribed
opioid antidiarrheal agent
with no CNS effects.
Which med?
35yo M in ED with 2-hour Activation of adenylyl cyclase
hx of sever fatigue and
dizziness. Had profuse,
watery diarrhea for 8 hours
despite a lack of oral
intake. Recently returned
from a medical relief trip to
a remove village in
Honduras. T
36.7 C, P 122/min, BP
90/50. PE shows dry skin
and decreased capillary
refill. Stool for occult blood
is negative; stool is gray
and turbid. Gram stain
shows gram-negative,
comma-shaped bacteria;
no erythrocytes of
leukocytes. MOA of toxin?
59yo F with gradual onset of cerebellum
lack of muscle control in her
left arm and leg. Sx 1 mo
ago after dx with
metastatic breast cancer.
PE shows ataxia of left
upper and lower
extremities. Muscle
strength, DTR, sensation,
proprioception normal.
… 3/281
, 4/5/25, 11:45 AM /NBME CBSE (usmle step 1)MEDICAL ACTUAL EXAM NEWEST VERSION 2024-2025 TESTBANK QUESTIONS AND CORRECT…
Metastatic tumor in which
location?
Newborn delivered at 38 Congenital cytomegalovirus infection
weeks' gestation weighs
1800 g. PE shows petechial
rash, microcephaly, and
hepatosplenomegaly.
Serologic test for CMV: IgG +
in mother, + in newborn;
IGM - in mother, + in
newborn.
Explanation?
… 4/281
