NR 565 – ADVANCED PHARMACOLOGY MIDTERM EXAM 2025
-CHAMBERLAN /ACTUAL COMPLETE 244 REAL EXAM
QUESTIONS ANDCORRECT ANSWERS (VERIFIED ANSWERS )
ALREADY GRADED A+.
What does 10% of codeine convert to/black box warning -
ANSWER-10% of each dose of codeine undergoes conversion
to morphine, the active form of codeine (led to death in children
and toxicity in infants through breast milk)
Black box warning for hydrocodone - ANSWER-products that
contain Tylenol
are associated with
hepatotoxicity
Black box warning opioids, fentanyl, oxycodone,
hydromorphone, oxymorphone
- ANSWER-respiratory
depression
black box warning for methadone - ANSWER-prolong QT
interval, fatal
dysrhythmias
,Do opioid agonist-antagonist have high or low potential for
abuse? - ANSWER-
low - when compared with opioid
agonists
If you switch a patient from oxycodone to buprenorphine
quickly what may we expect to see? - ANSWER-If given to a
patient who is physically dependent on a pure agonist, there
drugs can precipitate withdrawal
What level of pain is tramadol approved for - ANSWER-moderate
to moderately
severe
What schedule is tramadol classified as? - ANSWER-schedule
IV
What population should tramadol be AVOIDED in? -
ANSWER-pt's with
epilepsy, neurologic
disorders, elderly
What drugs should be avoided for patients taking tramadol? -
ANSWER-CNS
,depressants (benzo, alcohol), MAOI, SSRI, serotonin and
norepinephrine
reuptake inhibitors, tricyclic
antidepressants, triptans
What government branch declared the opioid crisis a public
health emergency?
- ANSWER-Health and Human
Services (HHS)
what are the top 5 priorities of HHS? - ANSWER-Improving
access to treatment
and recovery
services
Promoting use of overdose-
reversing drugs
Strengthening our understanding of the epidemic through
better public health
surveillance
Providing support for cutting edge research on pain
and addiction
Advancing better practices for pain
management
, What were provisions made to the guidelines for prescribing
opioids to noncancer patients? - ANSWER-Using opioids only
after non-opioid analgesics or more conservative methods
have failed
Discussing the benefits and risks for long term opioids with
patient
When possible, one prescriber, one pharmacy
Ensuring comprehensive follow up to assess efficacy and side
effects of treatment and monitor for signs of opioid abuse
Stopping opioids after an attempt at opioid rotation had
produced inadequate benefits
Fully documenting the entire process
When prescribing opioids should patient be initially started
on IR or ER? -
ANSWER-IR- lowest dose for shortest
amount of time
How are patients initially exposed to opioids? - ANSWER-
either recreationally
(illicitly) or in context of pain management in
medical setting
Which group of professionals are at greater risk for abusing? -
ANSWER-health
-CHAMBERLAN /ACTUAL COMPLETE 244 REAL EXAM
QUESTIONS ANDCORRECT ANSWERS (VERIFIED ANSWERS )
ALREADY GRADED A+.
What does 10% of codeine convert to/black box warning -
ANSWER-10% of each dose of codeine undergoes conversion
to morphine, the active form of codeine (led to death in children
and toxicity in infants through breast milk)
Black box warning for hydrocodone - ANSWER-products that
contain Tylenol
are associated with
hepatotoxicity
Black box warning opioids, fentanyl, oxycodone,
hydromorphone, oxymorphone
- ANSWER-respiratory
depression
black box warning for methadone - ANSWER-prolong QT
interval, fatal
dysrhythmias
,Do opioid agonist-antagonist have high or low potential for
abuse? - ANSWER-
low - when compared with opioid
agonists
If you switch a patient from oxycodone to buprenorphine
quickly what may we expect to see? - ANSWER-If given to a
patient who is physically dependent on a pure agonist, there
drugs can precipitate withdrawal
What level of pain is tramadol approved for - ANSWER-moderate
to moderately
severe
What schedule is tramadol classified as? - ANSWER-schedule
IV
What population should tramadol be AVOIDED in? -
ANSWER-pt's with
epilepsy, neurologic
disorders, elderly
What drugs should be avoided for patients taking tramadol? -
ANSWER-CNS
,depressants (benzo, alcohol), MAOI, SSRI, serotonin and
norepinephrine
reuptake inhibitors, tricyclic
antidepressants, triptans
What government branch declared the opioid crisis a public
health emergency?
- ANSWER-Health and Human
Services (HHS)
what are the top 5 priorities of HHS? - ANSWER-Improving
access to treatment
and recovery
services
Promoting use of overdose-
reversing drugs
Strengthening our understanding of the epidemic through
better public health
surveillance
Providing support for cutting edge research on pain
and addiction
Advancing better practices for pain
management
, What were provisions made to the guidelines for prescribing
opioids to noncancer patients? - ANSWER-Using opioids only
after non-opioid analgesics or more conservative methods
have failed
Discussing the benefits and risks for long term opioids with
patient
When possible, one prescriber, one pharmacy
Ensuring comprehensive follow up to assess efficacy and side
effects of treatment and monitor for signs of opioid abuse
Stopping opioids after an attempt at opioid rotation had
produced inadequate benefits
Fully documenting the entire process
When prescribing opioids should patient be initially started
on IR or ER? -
ANSWER-IR- lowest dose for shortest
amount of time
How are patients initially exposed to opioids? - ANSWER-
either recreationally
(illicitly) or in context of pain management in
medical setting
Which group of professionals are at greater risk for abusing? -
ANSWER-health
