Pharmacology NGR 6172 University of Florida NGR6172
Intro to Pharm_Unit 1 - Chap 1-16 Questions With
Complete Solutions
□ (Adrenergic or cholinergic) receptors mediate responses to
epinephrine and norepinephrine? Correct Answers Adrenergic
think "adrenelineRGIC"
□ (More or less) of the other medication would be needed?
Correct Answers More would be needed
□ A consequence of using an alpha antagonist might have what
effect on sexual function? Correct Answers Impotence failure
to ejaculate, and erectile dysfunction.
□ A disease or condition produced by a doctor or other health
care provider or drugs is known as what? Correct Answers An
iatrogenic effect
□ A drug that blocks alpha 1 receptors (alpha antagonist) would
be used to (increase or decrease) blood pressure? Correct
Answers Decrease
□ A drug that promotes transmitter release (increases or
decreases) receptor activation? Correct Answers Increases
□ A drug with a high therapeutic index is considered (safe or
unsafe)? Correct Answers Safe
,□ A drug with a narrow therapeutic range is (more or less)
dangerous? Correct Answers More dangerous
□ A form of tolerance that can be defined as a reduction in drug
responsiveness brought on by repeated dosing over a short time
is known as what? Correct Answers Tachyphylaxis
□ A list of drugs that have increased adverse events in the
elderly and are not considered appropriate for use in the elderly
is known as the _____________? Correct Answers The Beers
Criteria
□ A neonate is defined as (less or more) than 4 weeks of age?
Correct Answers A neonate is less than four weeks old
□ A patient with glucose-6-phosphate dehydrogenase (G6PD)
deficiency that takes aspirin or a sulfonamide is at risk for what
disorder? Correct Answers Hemolysis (red blood cell
destruction)
□ A patient with kidney or liver disease would require (higher or
lower) dosages of medicine? Correct Answers Lower doses
□ A patient with kidney or liver disease would require (higher or
lower) dosages of medicine? Correct Answers Lower doses
□ A warning that medical studies indicate that the drug carries a
significant risk of serious or even life-threatening adverse effects
is known as what? Correct Answers A Black Box Warning
,□ A warning that medical studies indicate that the drug carries a
significant risk of serious or even life-threatening adverse effects
is known as____________? Correct Answers A Black Box
Warning
□ Accelerated metabolism would lead to (increased or
decreased) blood levels of other drugs? Correct Answers
Decreased blood levels
□ According to the Beers Criteria which anticholinergic drugs
are potentially inappropriate for use in geriatric patients?
Correct Answers Drugs for overactive bladder such a
oxybutynin.
□ Activation of ___________________receptors have the
following effects: Blood vessels constriction sexual apparatus
ejaculation, and the smooth muscle contraction of the bladder
neck and prostatic capsule. Correct Answers Alpha 1 receptors
- SNS stimulation
□ Activation of (adrenergic or cholinergic) receptors would have
the following effect on: Glandular secretion- increase; Bronchi-
constriction; Bladder- voiding GI tract- salivation increased
gastric secretions, increased intestinal tone and motility, and
defecation; Heart- decrease heart rate; Eye- miosis
(constriction)? Correct Answers Cholinergic muscarinic
receptors.
□ Activation of Beta2 receptors has the following effects:
Correct Answers 1) Arterioles (heart lung/skeletal muscle)--
>dilation
, 2) Bronchi--> dilation
3) Uterus--> relaxation
4) Liver-->glycogenolysis
5) Skeletal muscle-->enhanced contraction
6) Liver--> glycogenolysis
□ Activation of dopamine receptors in the kidney (increases or
decreases) renal blood flow? Correct Answers Increases
□ Activity of CYP 2D6 is (lower or higher) in Asians and may
require (lower or higher) doses of drugs utilizing this
metabolizing enzyme? Correct Answers CYP 2D6 is lower,
requires lower dosing among Asians
□ Activity of CYP 2D6 is lower in Asians and may require
(lower or higher) doses of drugs utilizing this metabolizing
enzyme? Correct Answers - CYP 2D6 activity is lower. Lower
doses are needed in Asians.
- Think LOWER activity = LOWER doses
□ Agonist are molecules that (prevent or activate) receptors.
Correct Answers Activate
□ An adverse reaction triggered by succinylcholine as well as all
inhaled anesthetics in which temperature elevates due to
uncontrolled metabolic activity in muscle is
called______________________? Correct Answers Malignant
hyperthermia
Intro to Pharm_Unit 1 - Chap 1-16 Questions With
Complete Solutions
□ (Adrenergic or cholinergic) receptors mediate responses to
epinephrine and norepinephrine? Correct Answers Adrenergic
think "adrenelineRGIC"
□ (More or less) of the other medication would be needed?
Correct Answers More would be needed
□ A consequence of using an alpha antagonist might have what
effect on sexual function? Correct Answers Impotence failure
to ejaculate, and erectile dysfunction.
□ A disease or condition produced by a doctor or other health
care provider or drugs is known as what? Correct Answers An
iatrogenic effect
□ A drug that blocks alpha 1 receptors (alpha antagonist) would
be used to (increase or decrease) blood pressure? Correct
Answers Decrease
□ A drug that promotes transmitter release (increases or
decreases) receptor activation? Correct Answers Increases
□ A drug with a high therapeutic index is considered (safe or
unsafe)? Correct Answers Safe
,□ A drug with a narrow therapeutic range is (more or less)
dangerous? Correct Answers More dangerous
□ A form of tolerance that can be defined as a reduction in drug
responsiveness brought on by repeated dosing over a short time
is known as what? Correct Answers Tachyphylaxis
□ A list of drugs that have increased adverse events in the
elderly and are not considered appropriate for use in the elderly
is known as the _____________? Correct Answers The Beers
Criteria
□ A neonate is defined as (less or more) than 4 weeks of age?
Correct Answers A neonate is less than four weeks old
□ A patient with glucose-6-phosphate dehydrogenase (G6PD)
deficiency that takes aspirin or a sulfonamide is at risk for what
disorder? Correct Answers Hemolysis (red blood cell
destruction)
□ A patient with kidney or liver disease would require (higher or
lower) dosages of medicine? Correct Answers Lower doses
□ A patient with kidney or liver disease would require (higher or
lower) dosages of medicine? Correct Answers Lower doses
□ A warning that medical studies indicate that the drug carries a
significant risk of serious or even life-threatening adverse effects
is known as what? Correct Answers A Black Box Warning
,□ A warning that medical studies indicate that the drug carries a
significant risk of serious or even life-threatening adverse effects
is known as____________? Correct Answers A Black Box
Warning
□ Accelerated metabolism would lead to (increased or
decreased) blood levels of other drugs? Correct Answers
Decreased blood levels
□ According to the Beers Criteria which anticholinergic drugs
are potentially inappropriate for use in geriatric patients?
Correct Answers Drugs for overactive bladder such a
oxybutynin.
□ Activation of ___________________receptors have the
following effects: Blood vessels constriction sexual apparatus
ejaculation, and the smooth muscle contraction of the bladder
neck and prostatic capsule. Correct Answers Alpha 1 receptors
- SNS stimulation
□ Activation of (adrenergic or cholinergic) receptors would have
the following effect on: Glandular secretion- increase; Bronchi-
constriction; Bladder- voiding GI tract- salivation increased
gastric secretions, increased intestinal tone and motility, and
defecation; Heart- decrease heart rate; Eye- miosis
(constriction)? Correct Answers Cholinergic muscarinic
receptors.
□ Activation of Beta2 receptors has the following effects:
Correct Answers 1) Arterioles (heart lung/skeletal muscle)--
>dilation
, 2) Bronchi--> dilation
3) Uterus--> relaxation
4) Liver-->glycogenolysis
5) Skeletal muscle-->enhanced contraction
6) Liver--> glycogenolysis
□ Activation of dopamine receptors in the kidney (increases or
decreases) renal blood flow? Correct Answers Increases
□ Activity of CYP 2D6 is (lower or higher) in Asians and may
require (lower or higher) doses of drugs utilizing this
metabolizing enzyme? Correct Answers CYP 2D6 is lower,
requires lower dosing among Asians
□ Activity of CYP 2D6 is lower in Asians and may require
(lower or higher) doses of drugs utilizing this metabolizing
enzyme? Correct Answers - CYP 2D6 activity is lower. Lower
doses are needed in Asians.
- Think LOWER activity = LOWER doses
□ Agonist are molecules that (prevent or activate) receptors.
Correct Answers Activate
□ An adverse reaction triggered by succinylcholine as well as all
inhaled anesthetics in which temperature elevates due to
uncontrolled metabolic activity in muscle is
called______________________? Correct Answers Malignant
hyperthermia
