Test Bank For Modern Blood Banking & Transfusion Practices
7th Edition By Denise M Harmening 9780803668881 Chapter 1-
29 || A+ Guide
,Chapter q1 qRBCs qand qPlatelet qPreservation: qHistorical qPerspectives qand qCurrent qTrends
Multiple qChoice
Identify q the q choice q that q best q completes q the qstatement q or qanswers q the q question.
1. Which qmetabolic qpathway qis qresponsible qfor qgenerating q90% qof qthe qATP qfor qthe qRBC?
a. Pentose qphosphate qshunt c. Glycolysis
b. Luebering-Rapoport qshunt d. Methemoglobin qreductase
2. A qunit qof qblood qwas qreturned qto qthe qblood qbank qbefore qit qwas qspiked. qApparently qthe qpatient’s qIV
qfailed. qThe qunit qof qblood qwas qoutside qthe qblood qbank qfor q35 qminutes. qWhich qof qthe qstatements
qbelow qis qmost qaccurate?
a. The qunit qof qblood qshould qbe qdiscarded qimmediately.
b. The qunit qof q blood qcan qbe qreturned qto qinventory.
c. The qunit qof q blood qmust q be qtransfused qwithin q4 qhours qor qbe q discarded qat qthe qend qof qthat qtime.
d. The qunit qof q blood qmust q be qtransfused q with q24 qhours.
3. What qis qthe qaverage q diameter q of q a q platelet?
a. 5 q to q 10 q µm c. 1 q to q 2 q µm
b. 2 q to q 4 q µm d. 4 q to q6 q µm
4. In qthe qnormal qhemoglobin-oxygen qdissociation qcurve, qwhat qpercentage qof qoxygen qis qreleased qto
qthe qtissues qwhen qPO2 q averages q40 qmm qHg?
a. 75% c. 100%
b. 25% d. 50%
5. What qfactors qare qknown qto qinfluence qplatelet qmetabolism qand qfunction?
a. Storage qtemperature c. Platelet qcount
b. Initial qpH d. All q of qthe q above
6. Which qof qthe qfollowing qred qblood qcell qmorphologies qmay qbe qpresent qon qthe qperipheral qblood qsmear
qas qa qresult qof qloss qof qRBC qmembrane?
a. Spherocytes c. Burr q cells
b. Target qcells d. Schistocytes
7. What qdoes qthe qterm qautologous q transfusion qrefer qto?
a. A qparent qdonating qblood qfor qhis q or q her qchild
b. An qindividual qdonating qblood qfor qa qfriend
c. An qindividual qdonating qblood qfor qa qrelative
d. An qindividual q donating qblood qfor qhis qor qher qown qtransfusion
8. What qis qthe q primary qfunction q of q hemoglobin?
a. Iron qmetabolism c. Oxygen qtransport
b. Porphyrin qsynthesis d. Signal q transduction
9. All qof qthe qfollowing qareas qof qred qblood qcell qbiology qare qcrucial qfor qnormal qerythrocyte qsurvival q except:
a. Cellular qmetabolism. c. Site qof qthe qABO qantigen qattachment.
b. RBC qmembrane. d. Hemoglobin qstructure.
,q 10. q q What q is qthe q correct q biochemical q composition q of q the q RBC q membrane?
a. 52% qprotein, q40% qlipid, q8% qcarbohydrate
b. 40% qprotein, q8% qlipid, q52% qcarbohydrate
c. 8% qprotein, q52% qlipid, q40% qcarbohydrate
d. 8% qlipid, q40% qcarbohydrate, q52% qprotein
q 11. All qof qthe qfollowing qbiochemical q changes q are q associated qwith qloss qof qred qblood qcell q viability qupon qstorage
except:
a. Decreased qpH. c. Increased qATP qlevel.
b. Loss qof qred q blood qcell q function. d. Decreased qglucose qconsumption.
q 12. Which qred qblood q cell q preservative q has q a q storage qtime q of q 35 q days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
q 13. The q RBC q membrane q is q relatively qpermeable q to q all q of qthe qfollowing q except:
a. Chloride. c. Bicarbonate.
b. Sodium. d. q q Water.
q 14. qWhat qpercentage qof qplatelets qis qsequestered qin qthe qspleen qas qfunctional qreserve qafter qbeing
qreleased qfrom qthe qbone qmarrow?
a. 30% c. 10%
b. 50% d. 25%
q 15. q q What q is q the q major q biochemical q consideration q in q platelet q storage?
a. Glucose qmetabolism c. Production qof qcarbon qdioxide
b. Oxygen qsupply d. Regulation qof qpH
q16. qWhat qwould qthe qhemoglobin-oxygen qdissociation qcurve qdepict qin qa qpatient qexhibiting qclinical
qsigns qof qalkalosis?
a. Normal c. Shift qto qthe q right
b. Shift qto qthe q left d. None q of q the q above
q 17. Name q the qmain q lipid qcomponents q of q a qred q blood qcell q membrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin qA
q 18. The qABO q blood q groups q were q discovered q in q 1901 qby qwhom?
a. Charles q Drew c. Loutit qand qMollison
b. Karl q Landsteiner d. Edward qLindeman
q 19. q A q standing q order q of q platelets q was q shipped q to q your q facility q by q your q supplier. q It q was
q inadvertently q left q in qthe qcorner qof qthe qdepartment quntil qdiscovered q36 qhours qlater. qWhat qwould qthe
qappropriate qaction qbe qfor qthe qblood qbanker?
a. If qthe qtemperature qin qthe qbox qwas q22 q+/- q2°C qand qthe qplatelet qswirl qseemed qOK, qit
qwould qbe qOK qto qaccept qthe qunit qinto qinventory.
b. The qplatelets qhave qfallen qoutside qthe qsupplier’s qquality qassurance. qThe qunit qshould
qbe qdiscarded qbecause qthe qpH qhas qprobably qdropped qtoo qlow qand qplatelet
qactivation qhas qbeen qcompromised.
c. If qthe qtemperature qwas q 1°C qto q6°C qand qthe qplatelet q swirl q seemed qOK, qit qwould qbe qOK qto
, accept qthe qunit qinto qinventory.
d. If qthe qplatelets qappeared qOK qand qpassed qthe qplatelet qswirl qtest qafter qbeing
qplaced qon qthe qagitator, qthey qcould qbe qaccepted qinto qthe qinventory.
q 20. q q Which qmetabolic qpathway qpermits q the q accumulation qof q 2,3 qdiphosphoglycerate q (2,3-DPG)?
a. Glycolysis c. Pentose qphosphate qshunt
b. Luebering-Rapoport qshunt d. Methemoglobin qreductase
q 21. q q All q of qthe qfollowing qare q consistent q with qa q"shift q to qthe q right" q of qthe qhemoglobin-oxygen q dissociation
q curve
except:
a. Increased q 2,3-DPG.
b. 50% qO2 q saturation qto qtissues.
c. Decreased q2,3-DPG.
d. Decreased qhemoglobin qaffinity qfor qO2.
q 22. What qis q the q normal q platelet q count qrange q per q cubic qmillimeter?
a. 100 q to q 350 c. 50,000 qto q 200,000
b. 150,000 qto q 350,000 d. 350,000 q to q 500,000
q 23. What qcryoprotective q agent q is q added q to qred q blood qcells q upon q freezing?
a. Dextrose c. Glycerol
b. Adsol d. All q of qthe q above
q 24. q q If q platelets q are qto qbe q stored q for q 5 qdays q on q a qrotator, q what q is q the q optimal q storage q temperature?
a. 1°C q to q 6°C c. 35°C q to q 37°C
b. 20°C qto q 24°C d. 1°C q to q 10°C
q 25. What q role q do q platelets q play qin q hemostasis?
a. Maintenance qof qvascular qintegrity
b. Initial qarrest qof qbleeding qby qplatelet qplug qformation
c. Stabilization qof qthe qhemostatic qplug
d. All q of qthe qabove
q 26. Which qof qthe qfollowing qbest q describes q"integral" qmembrane q proteins?
a. Reside qat qthe qcytoplasmic qsurface qof qmembrane
b. Span qthe qentire qmembrane q surface
c. Form qthe qred q blood qcell q cytoskeleton
d. None q of q the q above
q 27. How qis q stroma-free qhemoglobin qsolution qprepared?
a. Outdated qred qblood qcells qare qconcentrated, qand qstroma qis qremoved.
b. Outdated qred qblood qcells qare qdiluted qwith qsaline, qand qstroma qis qremoved.
c. Outdated qred qblood qcells qare qlysed, qand qstroma qis q removed.
d. None q of q the q above
q 28. What qis q the q normal q life q span q of q an q RBC?
a. 100 q days c. 120 q hours
b. 120 q days d. 2 q days
q 29. q qRegarding qloss q of q RBC q membrane q deformability, q all q of q the q following qare q true q except:
a. Increase qin qATP qlevel.
b. Decrease qin qATP qlevel.
7th Edition By Denise M Harmening 9780803668881 Chapter 1-
29 || A+ Guide
,Chapter q1 qRBCs qand qPlatelet qPreservation: qHistorical qPerspectives qand qCurrent qTrends
Multiple qChoice
Identify q the q choice q that q best q completes q the qstatement q or qanswers q the q question.
1. Which qmetabolic qpathway qis qresponsible qfor qgenerating q90% qof qthe qATP qfor qthe qRBC?
a. Pentose qphosphate qshunt c. Glycolysis
b. Luebering-Rapoport qshunt d. Methemoglobin qreductase
2. A qunit qof qblood qwas qreturned qto qthe qblood qbank qbefore qit qwas qspiked. qApparently qthe qpatient’s qIV
qfailed. qThe qunit qof qblood qwas qoutside qthe qblood qbank qfor q35 qminutes. qWhich qof qthe qstatements
qbelow qis qmost qaccurate?
a. The qunit qof qblood qshould qbe qdiscarded qimmediately.
b. The qunit qof q blood qcan qbe qreturned qto qinventory.
c. The qunit qof q blood qmust q be qtransfused qwithin q4 qhours qor qbe q discarded qat qthe qend qof qthat qtime.
d. The qunit qof q blood qmust q be qtransfused q with q24 qhours.
3. What qis qthe qaverage q diameter q of q a q platelet?
a. 5 q to q 10 q µm c. 1 q to q 2 q µm
b. 2 q to q 4 q µm d. 4 q to q6 q µm
4. In qthe qnormal qhemoglobin-oxygen qdissociation qcurve, qwhat qpercentage qof qoxygen qis qreleased qto
qthe qtissues qwhen qPO2 q averages q40 qmm qHg?
a. 75% c. 100%
b. 25% d. 50%
5. What qfactors qare qknown qto qinfluence qplatelet qmetabolism qand qfunction?
a. Storage qtemperature c. Platelet qcount
b. Initial qpH d. All q of qthe q above
6. Which qof qthe qfollowing qred qblood qcell qmorphologies qmay qbe qpresent qon qthe qperipheral qblood qsmear
qas qa qresult qof qloss qof qRBC qmembrane?
a. Spherocytes c. Burr q cells
b. Target qcells d. Schistocytes
7. What qdoes qthe qterm qautologous q transfusion qrefer qto?
a. A qparent qdonating qblood qfor qhis q or q her qchild
b. An qindividual qdonating qblood qfor qa qfriend
c. An qindividual qdonating qblood qfor qa qrelative
d. An qindividual q donating qblood qfor qhis qor qher qown qtransfusion
8. What qis qthe q primary qfunction q of q hemoglobin?
a. Iron qmetabolism c. Oxygen qtransport
b. Porphyrin qsynthesis d. Signal q transduction
9. All qof qthe qfollowing qareas qof qred qblood qcell qbiology qare qcrucial qfor qnormal qerythrocyte qsurvival q except:
a. Cellular qmetabolism. c. Site qof qthe qABO qantigen qattachment.
b. RBC qmembrane. d. Hemoglobin qstructure.
,q 10. q q What q is qthe q correct q biochemical q composition q of q the q RBC q membrane?
a. 52% qprotein, q40% qlipid, q8% qcarbohydrate
b. 40% qprotein, q8% qlipid, q52% qcarbohydrate
c. 8% qprotein, q52% qlipid, q40% qcarbohydrate
d. 8% qlipid, q40% qcarbohydrate, q52% qprotein
q 11. All qof qthe qfollowing qbiochemical q changes q are q associated qwith qloss qof qred qblood qcell q viability qupon qstorage
except:
a. Decreased qpH. c. Increased qATP qlevel.
b. Loss qof qred q blood qcell q function. d. Decreased qglucose qconsumption.
q 12. Which qred qblood q cell q preservative q has q a q storage qtime q of q 35 q days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
q 13. The q RBC q membrane q is q relatively qpermeable q to q all q of qthe qfollowing q except:
a. Chloride. c. Bicarbonate.
b. Sodium. d. q q Water.
q 14. qWhat qpercentage qof qplatelets qis qsequestered qin qthe qspleen qas qfunctional qreserve qafter qbeing
qreleased qfrom qthe qbone qmarrow?
a. 30% c. 10%
b. 50% d. 25%
q 15. q q What q is q the q major q biochemical q consideration q in q platelet q storage?
a. Glucose qmetabolism c. Production qof qcarbon qdioxide
b. Oxygen qsupply d. Regulation qof qpH
q16. qWhat qwould qthe qhemoglobin-oxygen qdissociation qcurve qdepict qin qa qpatient qexhibiting qclinical
qsigns qof qalkalosis?
a. Normal c. Shift qto qthe q right
b. Shift qto qthe q left d. None q of q the q above
q 17. Name q the qmain q lipid qcomponents q of q a qred q blood qcell q membrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin qA
q 18. The qABO q blood q groups q were q discovered q in q 1901 qby qwhom?
a. Charles q Drew c. Loutit qand qMollison
b. Karl q Landsteiner d. Edward qLindeman
q 19. q A q standing q order q of q platelets q was q shipped q to q your q facility q by q your q supplier. q It q was
q inadvertently q left q in qthe qcorner qof qthe qdepartment quntil qdiscovered q36 qhours qlater. qWhat qwould qthe
qappropriate qaction qbe qfor qthe qblood qbanker?
a. If qthe qtemperature qin qthe qbox qwas q22 q+/- q2°C qand qthe qplatelet qswirl qseemed qOK, qit
qwould qbe qOK qto qaccept qthe qunit qinto qinventory.
b. The qplatelets qhave qfallen qoutside qthe qsupplier’s qquality qassurance. qThe qunit qshould
qbe qdiscarded qbecause qthe qpH qhas qprobably qdropped qtoo qlow qand qplatelet
qactivation qhas qbeen qcompromised.
c. If qthe qtemperature qwas q 1°C qto q6°C qand qthe qplatelet q swirl q seemed qOK, qit qwould qbe qOK qto
, accept qthe qunit qinto qinventory.
d. If qthe qplatelets qappeared qOK qand qpassed qthe qplatelet qswirl qtest qafter qbeing
qplaced qon qthe qagitator, qthey qcould qbe qaccepted qinto qthe qinventory.
q 20. q q Which qmetabolic qpathway qpermits q the q accumulation qof q 2,3 qdiphosphoglycerate q (2,3-DPG)?
a. Glycolysis c. Pentose qphosphate qshunt
b. Luebering-Rapoport qshunt d. Methemoglobin qreductase
q 21. q q All q of qthe qfollowing qare q consistent q with qa q"shift q to qthe q right" q of qthe qhemoglobin-oxygen q dissociation
q curve
except:
a. Increased q 2,3-DPG.
b. 50% qO2 q saturation qto qtissues.
c. Decreased q2,3-DPG.
d. Decreased qhemoglobin qaffinity qfor qO2.
q 22. What qis q the q normal q platelet q count qrange q per q cubic qmillimeter?
a. 100 q to q 350 c. 50,000 qto q 200,000
b. 150,000 qto q 350,000 d. 350,000 q to q 500,000
q 23. What qcryoprotective q agent q is q added q to qred q blood qcells q upon q freezing?
a. Dextrose c. Glycerol
b. Adsol d. All q of qthe q above
q 24. q q If q platelets q are qto qbe q stored q for q 5 qdays q on q a qrotator, q what q is q the q optimal q storage q temperature?
a. 1°C q to q 6°C c. 35°C q to q 37°C
b. 20°C qto q 24°C d. 1°C q to q 10°C
q 25. What q role q do q platelets q play qin q hemostasis?
a. Maintenance qof qvascular qintegrity
b. Initial qarrest qof qbleeding qby qplatelet qplug qformation
c. Stabilization qof qthe qhemostatic qplug
d. All q of qthe qabove
q 26. Which qof qthe qfollowing qbest q describes q"integral" qmembrane q proteins?
a. Reside qat qthe qcytoplasmic qsurface qof qmembrane
b. Span qthe qentire qmembrane q surface
c. Form qthe qred q blood qcell q cytoskeleton
d. None q of q the q above
q 27. How qis q stroma-free qhemoglobin qsolution qprepared?
a. Outdated qred qblood qcells qare qconcentrated, qand qstroma qis qremoved.
b. Outdated qred qblood qcells qare qdiluted qwith qsaline, qand qstroma qis qremoved.
c. Outdated qred qblood qcells qare qlysed, qand qstroma qis q removed.
d. None q of q the q above
q 28. What qis q the q normal q life q span q of q an q RBC?
a. 100 q days c. 120 q hours
b. 120 q days d. 2 q days
q 29. q qRegarding qloss q of q RBC q membrane q deformability, q all q of q the q following qare q true q except:
a. Increase qin qATP qlevel.
b. Decrease qin qATP qlevel.
