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TEST BANK FOR MODERN BLOOD BANKING
hh hh hh hh hh
& TRANSFUSION PRACTICES 7TH EDITION
hh hh hh hh hh
BY DENISE M HARMENING
hh hh hh hh
9780803668881 CHAPTER 1-29 COMPLETE
hh hh hh
GUIDE hh
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice hh
Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis hh hh
b. Luebering-Rapoport shunt d. Methemoglobin reductase hh h h hh
2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
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The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
accurate? hh
a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory. hh hh hh hh hh hh hh hh
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm hh hh hh c. 1 to 2 µm hh hh hh
b. 2 to 4 µm hh hh hh d. 4 to 6 µmh h h h hh hh hh
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the
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tissues when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% h h
5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count hh hh
b. Initial pH d. All of the above
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
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result of loss of RBC membrane?
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a. Spherocytes c. Burr cells hh
b. Target cells d. Schistocytes hh h h
7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
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b. An individual donating blood for a friend hh hh hh hh hh hh
c. An individual donating blood for a relative hh hh hh hh hh hh
d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism c. Oxygen transport
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b. Porphyrin synthesis d. Signal transduction hh h h hh
9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
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h h 10. What is the correct biochemical composition of the RBC membrane?
h h hh hh hh hh hh hh hh hh hh
a. 52% protein, 40% lipid, 8% carbohydrate hh hh hh hh hh
b. 40% protein, 8% lipid, 52% carbohydrate hh hh hh hh hh
c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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h h 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
a. Decreased pH. c. Increased ATP level. hh hh hh
b. Loss of red blood cell function. d. Decreased glucose consumption.
hh hh hh hh hh h h hh hh
h h 12. Which red blood cell preservative has a storage time of 35 days?
h h hh hh hh hh hh hh hh hh hh hh hh
a. ACD c. AS-1
b. CPDA-1 d. CPD h h h h
h h 13. The RBC membrane is relatively permeable to all of the following except:
h h hh hh hh hh hh hh hh hh hh hh hh
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. h h
h h 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
the bone marrow?
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a. 30% c. 10%
b. 50% d. 25% h h h h
h h 15. What is the major biochemical consideration in platelet storage?
h h hh hh hh hh hh hh hh hh
a. Glucose metabolism c. Production of carbon dioxide
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b. Oxygen supply d. Regulation of pH
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h h 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs
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of alkalosis?
hh hh
a. Normal c. Shift to the right hh hh hh
b. Shift to the left d. None of the above
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h h 17. Name the main lipid components of a red blood cell membrane.
h h hh hh hh hh hh hh hh hh hh hh
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A h h hh
h h 18. The ABO blood groups were discovered in 1901 by whom?
h h hh hh hh hh hh hh hh hh hh
a. Charles Drew c. Loutit and Mollison
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b. Karl Landsteiner d. Edward Lindeman
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h h 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
the corner of the department until discovered 36 hours later. What would the appropriate action be for the
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
blood banker?
hh hh
a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
be OK to accept the unit into inventory.
hh hh hh hh hh hh hh hh
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
hh hh hh hh hh hh hh hh hh hh hh hh
discarded because the pH has probably dropped too low and platelet activation has
hh hh hh hh hh hh hh hh hh hh hh hh hh
been compromised.
hh hh
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
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hh hh hh hh hh hh hh hh hh hh hh hh hh
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accept the unit into inventory. hh hh hh hh
d. If the platelets appeared OK and passed the platelet swirl test after being placed on
hh hh hh hh hh hh hh hh hh hh hh hh hh hh
the agitator, they could be accepted into the inventory.
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h h 20. h Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
h hh hh hh hh hh hh hh hh hh
a. Glycolysis c. Pentose phosphate shunt hh hh
b. Luebering-Rapoport shunt d. Methemoglobin reductase hh h h hh
h h 21. h All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation curve
h hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
except:
a. Increased 2,3-DPG. hh
b. 50% O2 saturation to tissues.
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c. Decreased 2,3-DPG. hh
d. Decreased hemoglobin affinity for O2. hh hh hh hh
h h 22. h What is the normal platelet count range per cubic millimeter?
h hh hh hh hh hh hh hh hh hh
a. 100 to 350 hh hh c. 50,000 to 200,000 hh hh
b. 150,000 to 350,000 d. 350,000 to 500,000
hh hh h h hh hh
h h 23. h What cryoprotective agent is added to red blood cells upon freezing?
h hh hh hh hh hh hh hh hh hh hh
a. Dextrose c. Glycerol
b. Adsol d. All of the above h h hh hh hh
h h 24. h If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?
h hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
a. 1°C to 6°C hh hh c. 35°C to 37°C hh hh
b. 20°C to 24°C hh d. 1°C to 10°C
hh h h hh hh
h h 25. h h What role do platelets play in hemostasis?
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a. Maintenance of vascular integrity hh hh hh
b. Initial arrest of bleeding by platelet plug formation
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c. Stabilization of the hemostatic plug hh hh hh hh
d. All of the above
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h h 26. h h Which of the following best describes "integral" membrane proteins?
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a. Reside at the cytoplasmic surface of membrane
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b. Span the entire membrane surface
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c. Form the red blood cell cytoskeleton
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d. None of the above hh hh hh
h h 27. h h How is stroma-free hemoglobin solution prepared?
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a. Outdated red blood cells are concentrated, and stroma is removed.
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b. Outdated red blood cells are diluted with saline, and stroma is removed.
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c. Outdated red blood cells are lysed, and stroma is removed.
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d. None of the above hh hh hh
h h 28. h What is the normal life span of an RBC?
h hh hh hh hh hh hh hh hh
a. 100 days hh c. 120 hours hh
b. 120 days hh d. 2 days h h hh
h h 29. h Regarding loss of RBC membrane deformability, all of the following are true except:
h hh hh hh hh hh hh hh hh hh hh hh hh
a. Increase in ATP level. hh hh hh
b. Decrease in ATP level. hh hh hh
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hh hh hh hh hh hh hh hh hh hh hh hh hh
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TEST BANK FOR MODERN BLOOD BANKING
hh hh hh hh hh
& TRANSFUSION PRACTICES 7TH EDITION
hh hh hh hh hh
BY DENISE M HARMENING
hh hh hh hh
9780803668881 CHAPTER 1-29 COMPLETE
hh hh hh
GUIDE hh
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
hh hh hh hh hh hh hh hh hh hh
Multiple Choice hh
Identify the choice that best completes the statement or answers the question.
hh hh hh hh hh hh hh hh hh hh hh
1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
hh hh hh hh hh hh hh hh hh hh hh hh hh
a. Pentose phosphate shunt c. Glycolysis hh hh
b. Luebering-Rapoport shunt d. Methemoglobin reductase hh h h hh
2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
accurate? hh
a. The unit of blood should be discarded immediately.
hh hh hh hh hh hh hh
b. The unit of blood can be returned to inventory. hh hh hh hh hh hh hh hh
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm hh hh hh c. 1 to 2 µm hh hh hh
b. 2 to 4 µm hh hh hh d. 4 to 6 µmh h h h hh hh hh
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the
hh hh hh hh hh hh hh hh hh hh hh hh hh
tissues when PO2 averages 40 mm Hg?
hh hh hh h h hh hh hh
a. 75% c. 100%
b. 25% d. 50% h h
5. What factors are known to influence platelet metabolism and function?
hh hh hh hh hh hh hh hh hh
a. Storage temperature c. Platelet count hh hh
b. Initial pH d. All of the above
hh h h hh hh hh
6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
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result of loss of RBC membrane?
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a. Spherocytes c. Burr cells hh
b. Target cells d. Schistocytes hh h h
7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
hh hh hh hh hh hh hh hh
b. An individual donating blood for a friend hh hh hh hh hh hh
c. An individual donating blood for a relative hh hh hh hh hh hh
d. An individual donating blood for his or her own transfusion
hh hh hh hh hh hh hh hh hh
8. What is the primary function of hemoglobin?
hh hh hh hh hh hh
a. Iron metabolism c. Oxygen transport
hh hh
b. Porphyrin synthesis d. Signal transduction hh h h hh
9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
hh h h hh
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h h 10. What is the correct biochemical composition of the RBC membrane?
h h hh hh hh hh hh hh hh hh hh
a. 52% protein, 40% lipid, 8% carbohydrate hh hh hh hh hh
b. 40% protein, 8% lipid, 52% carbohydrate hh hh hh hh hh
c. 8% protein, 52% lipid, 40% carbohydrate
hh hh hh hh hh
d. 8% lipid, 40% carbohydrate, 52% protein
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h h 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
h h hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
except:
a. Decreased pH. c. Increased ATP level. hh hh hh
b. Loss of red blood cell function. d. Decreased glucose consumption.
hh hh hh hh hh h h hh hh
h h 12. Which red blood cell preservative has a storage time of 35 days?
h h hh hh hh hh hh hh hh hh hh hh hh
a. ACD c. AS-1
b. CPDA-1 d. CPD h h h h
h h 13. The RBC membrane is relatively permeable to all of the following except:
h h hh hh hh hh hh hh hh hh hh hh hh
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. h h
h h 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
the bone marrow?
hh hh hh
a. 30% c. 10%
b. 50% d. 25% h h h h
h h 15. What is the major biochemical consideration in platelet storage?
h h hh hh hh hh hh hh hh hh
a. Glucose metabolism c. Production of carbon dioxide
hh hh hh hh
b. Oxygen supply d. Regulation of pH
hh h h hh hh
h h 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs
hh hh hh hh hh hh hh hh hh hh hh hh hh
of alkalosis?
hh hh
a. Normal c. Shift to the right hh hh hh
b. Shift to the left d. None of the above
hh hh hh h h hh hh hh
h h 17. Name the main lipid components of a red blood cell membrane.
h h hh hh hh hh hh hh hh hh hh hh
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A h h hh
h h 18. The ABO blood groups were discovered in 1901 by whom?
h h hh hh hh hh hh hh hh hh hh
a. Charles Drew c. Loutit and Mollison
hh hh hh
b. Karl Landsteiner d. Edward Lindeman
hh h h hh
h h 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
the corner of the department until discovered 36 hours later. What would the appropriate action be for the
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
blood banker?
hh hh
a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
be OK to accept the unit into inventory.
hh hh hh hh hh hh hh hh
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
hh hh hh hh hh hh hh hh hh hh hh hh
discarded because the pH has probably dropped too low and platelet activation has
hh hh hh hh hh hh hh hh hh hh hh hh hh
been compromised.
hh hh
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
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hh hh hh hh hh hh hh hh hh hh hh hh hh
05:00
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accept the unit into inventory. hh hh hh hh
d. If the platelets appeared OK and passed the platelet swirl test after being placed on
hh hh hh hh hh hh hh hh hh hh hh hh hh hh
the agitator, they could be accepted into the inventory.
hh hh hh hh hh hh hh hh hh
h h 20. h Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
h hh hh hh hh hh hh hh hh hh
a. Glycolysis c. Pentose phosphate shunt hh hh
b. Luebering-Rapoport shunt d. Methemoglobin reductase hh h h hh
h h 21. h All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation curve
h hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
except:
a. Increased 2,3-DPG. hh
b. 50% O2 saturation to tissues.
hh hh hh hh
c. Decreased 2,3-DPG. hh
d. Decreased hemoglobin affinity for O2. hh hh hh hh
h h 22. h What is the normal platelet count range per cubic millimeter?
h hh hh hh hh hh hh hh hh hh
a. 100 to 350 hh hh c. 50,000 to 200,000 hh hh
b. 150,000 to 350,000 d. 350,000 to 500,000
hh hh h h hh hh
h h 23. h What cryoprotective agent is added to red blood cells upon freezing?
h hh hh hh hh hh hh hh hh hh hh
a. Dextrose c. Glycerol
b. Adsol d. All of the above h h hh hh hh
h h 24. h If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?
h hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
a. 1°C to 6°C hh hh c. 35°C to 37°C hh hh
b. 20°C to 24°C hh d. 1°C to 10°C
hh h h hh hh
h h 25. h h What role do platelets play in hemostasis?
hh hh hh hh hh hh
a. Maintenance of vascular integrity hh hh hh
b. Initial arrest of bleeding by platelet plug formation
hh hh hh hh hh hh hh
c. Stabilization of the hemostatic plug hh hh hh hh
d. All of the above
hh hh hh
h h 26. h h Which of the following best describes "integral" membrane proteins?
hh hh hh hh hh hh hh hh
a. Reside at the cytoplasmic surface of membrane
hh hh hh hh hh hh
b. Span the entire membrane surface
hh hh hh hh
c. Form the red blood cell cytoskeleton
hh hh hh hh hh
d. None of the above hh hh hh
h h 27. h h How is stroma-free hemoglobin solution prepared?
hh hh hh hh hh
a. Outdated red blood cells are concentrated, and stroma is removed.
hh hh hh hh hh hh hh hh hh
b. Outdated red blood cells are diluted with saline, and stroma is removed.
hh hh hh hh hh hh hh hh hh hh hh
c. Outdated red blood cells are lysed, and stroma is removed.
hh hh hh hh hh hh hh hh hh
d. None of the above hh hh hh
h h 28. h What is the normal life span of an RBC?
h hh hh hh hh hh hh hh hh
a. 100 days hh c. 120 hours hh
b. 120 days hh d. 2 days h h hh
h h 29. h Regarding loss of RBC membrane deformability, all of the following are true except:
h hh hh hh hh hh hh hh hh hh hh hh hh
a. Increase in ATP level. hh hh hh
b. Decrease in ATP level. hh hh hh
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hh hh hh hh hh hh hh hh hh hh hh hh hh
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