Midterm Exam: NR5 07/ NR 5 07 (Latest 2024/ 2025 Update) Advanced Pathophysiology Review| Questions and Verified Answers| 100% Correct |Grade A – Chamberlain Q: Autoimmune disease... Answer: .... can be familial. Q: Hypersensitivity: Type 4 Answer: -Delayed -T-cell mediated - Does NOT involve antigen/antibody complexes Q: Type 2 & 4 Hypersensitivity relationship Answer: (Type 2) Organ rejection involves cytotoxicity -> (Type 4) T -cells also involved in organ rejection -> (Type 2) Antigens from target cells stimulate T -cells to differentiate into cytotoxic T -
cells -> (Type 4) T - cells have cytotoxic activity along with he lper T -cells involved in delayed hypersen - sitivity Q: Hypersensitivity Type 4 RASH Answer: -Delayed several days following contact (e.g. poison ivy) -contact dermatitis consisting of lesions only at the site of contact with the allergen Q: Treatment of Type 4 Rash Answer: Topical corticosteroids No epi or antihistamines as doesn't act on mast cells/H1 receptors Q: primary immunodeficiency Answer: Most primary immune deficiencies are the result of a single gene defect *something lacking in the immune system itself Q: secondary immunodeficiency Answer: Immunodeficiency as a complication of some other physiologic condition or disease Q: Example of primary immunodeficiency Answer: B-lymphocyte Deficiency Q: Example of secondary immunodeficiency Answer: Malnutrition is a cause of this HIV pt gets pneumocystis carinii Q: Recycling of RBCs Answer: Provides the body with most of its iron stores Q: Mean Corpuscular Hemoglobin Concentration (MCHC) Answer: Measure of the av - erage concentration of hemoglobin inside a single red blood cell (color) Q: Normochromic anemias Answer: MCHC 32 -36% Hemolytic Aplastic Post-hemorrhagic Q: Hypochromic Anemias Answer: Pale RBCs Sideroblastic anemia Iron deficiency anemia Thalassemia Q: Hyperchromic anemias Answer: Liver disease Sickle cell Hyperthyroidism Hereditary spherocytosis Q: iron deficiency anemia Answer: microcytic, hypochromic Caused by disorder of hb synthesis
cells -> (Type 4) T - cells have cytotoxic activity along with he lper T -cells involved in delayed hypersen - sitivity Q: Hypersensitivity Type 4 RASH Answer: -Delayed several days following contact (e.g. poison ivy) -contact dermatitis consisting of lesions only at the site of contact with the allergen Q: Treatment of Type 4 Rash Answer: Topical corticosteroids No epi or antihistamines as doesn't act on mast cells/H1 receptors Q: primary immunodeficiency Answer: Most primary immune deficiencies are the result of a single gene defect *something lacking in the immune system itself Q: secondary immunodeficiency Answer: Immunodeficiency as a complication of some other physiologic condition or disease Q: Example of primary immunodeficiency Answer: B-lymphocyte Deficiency Q: Example of secondary immunodeficiency Answer: Malnutrition is a cause of this HIV pt gets pneumocystis carinii Q: Recycling of RBCs Answer: Provides the body with most of its iron stores Q: Mean Corpuscular Hemoglobin Concentration (MCHC) Answer: Measure of the av - erage concentration of hemoglobin inside a single red blood cell (color) Q: Normochromic anemias Answer: MCHC 32 -36% Hemolytic Aplastic Post-hemorrhagic Q: Hypochromic Anemias Answer: Pale RBCs Sideroblastic anemia Iron deficiency anemia Thalassemia Q: Hyperchromic anemias Answer: Liver disease Sickle cell Hyperthyroidism Hereditary spherocytosis Q: iron deficiency anemia Answer: microcytic, hypochromic Caused by disorder of hb synthesis
