Please check the examination details below before entering your candidate
information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel
Level 3 GCE
Monday 15 May
2023
Morning (Time: 1 hour 30
8BN0/01
minutes) Pap
er
reference
Biology A (Salters Nuffield)
Advanced Subsidiary
PAPER 1: Lifestyle, Transport, Genes and
Health
You must have: Total Marks
Scientific calculator, HB
pencil, ruler
Instructions
• Use black ink or ball-point pen.
• Fill in the boxes at the top of this page with
centre number and candidate number.
• Answer all
your name,
• Show all your working out in calculations and include units
• Answer
where the questions
appropriate.
questions.
in themay
– there spaces
be more space than you need.
Information
provided
• The total mark for this paper is 80.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend
• on each question. You may use a scientific calculator.
• In questions marked with an asterisk (*), marks will be awarded
for your ability to structure your answer logically, showing how the
points that you make are related or follow on from each other
where appropriate.
Advice
• Read each question carefully before you start to answer it.
• Try to answer every
• Check your answers if you have time at the end.
Turn ove
question.
, Answer ALL questions.
Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If
you change your mind about an answer, put a line through the box
and then mark your new answer with a
cross .
1 The diagram shows a DNA nucleotide.
O
(a) (i) Complete the diagram to show how a complementary pair
of nucleotides would appear in a DNA molecule.
(2)
(ii) Name two bonds formed between nucleotides in the
process of DNA replication.
(2)
1 ............................................................................................................................... ............................................................................
................................................... ..................
2 ............................................................................................................................... ............................................................................
................................................... ..................
, (b) The diagram shows the structure of a DNA nucleotide and a
modified nucleotide called CeNA.
O
DNA nucleotide CeNA nucleotide
Give one difference in the structure of these two
molecules. (1)
............................................................................................................................... ................................................................................
............................................... .......................
............................................................................................................................... ................................................................................
............................................... .......................
............................................................................................................................... ................................................................................
............................................... .......................
(Total for Question 1 = 5
marks)
, 2 The human circulatory system is composed of the heart and
blood vessels.
(a) The graph shows pressure changes in the aorta, left atrium
and left ventricle during the cardiac cycle.
20 Left
ventricle
Left
15 atrium
R Aorta
Blood 10 Q
pressure S
/ kPa 5 P
0
–5
0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9
Time / s
(i) At which part of the graph is the left atrioventricular valve
starting to close? (1)
A P
B Q
C R
D S
(ii) At which part of the graph is a semilunar valve opening? (1)
A P
B Q
C R
D S
information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel
Level 3 GCE
Monday 15 May
2023
Morning (Time: 1 hour 30
8BN0/01
minutes) Pap
er
reference
Biology A (Salters Nuffield)
Advanced Subsidiary
PAPER 1: Lifestyle, Transport, Genes and
Health
You must have: Total Marks
Scientific calculator, HB
pencil, ruler
Instructions
• Use black ink or ball-point pen.
• Fill in the boxes at the top of this page with
centre number and candidate number.
• Answer all
your name,
• Show all your working out in calculations and include units
• Answer
where the questions
appropriate.
questions.
in themay
– there spaces
be more space than you need.
Information
provided
• The total mark for this paper is 80.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend
• on each question. You may use a scientific calculator.
• In questions marked with an asterisk (*), marks will be awarded
for your ability to structure your answer logically, showing how the
points that you make are related or follow on from each other
where appropriate.
Advice
• Read each question carefully before you start to answer it.
• Try to answer every
• Check your answers if you have time at the end.
Turn ove
question.
, Answer ALL questions.
Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If
you change your mind about an answer, put a line through the box
and then mark your new answer with a
cross .
1 The diagram shows a DNA nucleotide.
O
(a) (i) Complete the diagram to show how a complementary pair
of nucleotides would appear in a DNA molecule.
(2)
(ii) Name two bonds formed between nucleotides in the
process of DNA replication.
(2)
1 ............................................................................................................................... ............................................................................
................................................... ..................
2 ............................................................................................................................... ............................................................................
................................................... ..................
, (b) The diagram shows the structure of a DNA nucleotide and a
modified nucleotide called CeNA.
O
DNA nucleotide CeNA nucleotide
Give one difference in the structure of these two
molecules. (1)
............................................................................................................................... ................................................................................
............................................... .......................
............................................................................................................................... ................................................................................
............................................... .......................
............................................................................................................................... ................................................................................
............................................... .......................
(Total for Question 1 = 5
marks)
, 2 The human circulatory system is composed of the heart and
blood vessels.
(a) The graph shows pressure changes in the aorta, left atrium
and left ventricle during the cardiac cycle.
20 Left
ventricle
Left
15 atrium
R Aorta
Blood 10 Q
pressure S
/ kPa 5 P
0
–5
0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9
Time / s
(i) At which part of the graph is the left atrioventricular valve
starting to close? (1)
A P
B Q
C R
D S
(ii) At which part of the graph is a semilunar valve opening? (1)
A P
B Q
C R
D S
