Exam 1: NSG552/ NSG 552 (Latest 2023/2024) Psychopharmacology Exam Review| Complete Guide with Verified Answers| 100% Correct

Exam 1: NSG552/ NSG 552 (Latest 2023/2024) Psychopharmacology Exam Review| Complete Guide with Verified Answers| 100% Correct Q: What antipsychotic medication is likely to have the least amount of weight gain? Answer: Ziprasidone Q: What antipsychotic medication is least likely to result in metabolic syn- drome? Answer: Haloperidol Q: What antipsychotic medications are least likely to cause increased pro- lactin? Answer: Aripiprazole, Asenapine, Clozapine, Quetiapine, Olanzapine Q: What antipsychotic medications are least likely to cause QT elongation?- Answer: Haloperidol, Olanzapine, Aripiprazole Q: What antipsychotic medications are least likely to cause EPS? Answer: Clozapine, Quetiapine Q: What are the four steps to monitor for metabolic syndrome? Answer: 1) Obtain Baseline - weight, BMI, fasting glucose and lipids, BP, EKG 2) Recheck weight+BMI at 4 weeks, 8 weeks, 12 weeks, 6 months, quarterly, and annually 3) Check fasting glucose and lipids at Biannually 4) If metabolic syndrome is suspected then switch agents, lower dose, and/or add metformin Q: T/F ETOH use increases risk for TD? Answer: TRUE Q: Akasthesia Answer: A state of agitation, distress, and restlessness that is an occasional side-effect of antipsychotic and antidepressant drugs Q: Dystonia Answer: Involuntary muscle contraction that cause repetitive or twisting move- ments. Q: Psuedo-parkinsonism Answer: AKA DRUG INDUCED PARKINSONISM is a reversible condition that resembles parkinsonism. Parkinsonism refers to any condition that causes the movement irregularities seen in Parkinson's disease, a brain disorder. Q: How to manage EPS? Answer: 1) Add benztropine, Benadryl, amantadine DO NOT USE FOR PROPHLAYXIS DUE TO SIDE EFFECTS 2) Or Consider switching medications. (EPS is less likely to be caused by clozapine or quetiapine) Q: Name 3 options to treat psychotic agitation? Answer: 1) PO risperidone + lorazepam 2) IM haloperidol + lorazepam 3) Asenapine can be given sublingual to TOP OFF or provide additive effect to current APS treatment Q: Clozapine Answer: Use only in drug-resistant tx of schizophrenia. Do NOT use in teens. Most common side effects: dyslipidemia, hyperglycemia, weight gain, drowsiness, sialorrhea, tachycardia, dizziness, constipation, hypotension, headache, EPS, di- aphoresis, xerostomia, tremor, nausea, vomiting, fever, visual/sleep disturbance, dyspepsia, HTN, restlessness, confusion, impaired body temperature regulation Most severe side effects: agranulocytosis, neutropenia, seizures, myocarditis, car- diomyopathy, mitral valve incompetence, cardiovascular collapse, QT prolongation, arrhythmia, torsades de pointes, stroke, syncope, orthostatic hypotension, NMS, TD, dystonia, heat stroke, severe constipation, intestinal infarction/ischemia, GI obstruction, paralytic ileus, hepatotoxicity, hepatic failure, angle closure glaucoma, PE, DM, hypersensitivity, erythema multiforme, SJS, eosinophilia, withdrawal sx if abrupt D/C Q: What receptor is most responsible for EPS? Answer: