Chapter 7, Unit 4 Questions, UNE BIOL
1020 Unit 5 Questions, UNE
Microbiology Final Exam and Actual
Answers.
The link between macrophages and neutrophils is that both cells
A.Have large granules in the cytoplasm
B.Are phagocytes
C. Have a life span of about 10 years
D. Lack a nucleus
E. recognize tumor and virus infected cells and kill them - Answer B. Are phagocytes
Which of the following are mechanical barriers in the body's first line of defense?
A.Peristaltic removal of mucus entrapped pathogens
B.Intact dermis and epidermis
C.Normal microbiota like Lactobacillus lining the vaginal tract
D.Defensins and lactoferrin
E. lysozyme and peroxidase - Answer B.Intact dermis and epidermis
What is a phagolysosome?
A. When a phagosome releases defensin and starts producing hydrogen peroxide
B. When a phagosome releases histamine and other allergic stimulants in tissues
C. When a phagocyte starts to produce lysosomes
D. When a phagosome fuses with several lysosomes to digest a pathogen
E. When a phagocyte moves with amoeba-like locomotion - Answer D. When a phagosome
fuses with several lysosomes to digest a pathogen
The innate immune system recognizes pathogens by identifying unique microbial sequences not
found on host cells. This system of recognition is called
A. AMP
B. PAMP
C. TLR
D. MHC
E. ROS - Answer B. PAMP
,Which of the following are cytokines produced in response to invasion by viruses
A. RIG-1
B. Interferon
C. Histamine
D. Interleukin
E. Colony-stimulating factor - Answer B. Interferon
Macrophages are involved in
A. Activating the acquired immune response
B. Phagocytosis
C. Release of cytokines and lipid mediators that will trigger an inflammatory response
D. Granuloma formation
E. All of the choices are correct - Answer E. All of the choices are correct
Which one of the following is not a product of the lysosome?
A. Perioxidase enzyme
B. Nitric Acid (NO)
C. Cytokines
D. Superoxide anion (O2-)
E. Peptidoglycan-degrading enzyme - Answer C. Cytokines
Three types of leukocytes that contain granules with lysosomes - Answer Neutrophils,
basophils, eusinophils
In the tissues, these mature into macrophages - Answer Monocytes
These cells are found in large numbers in allergic reactions - Answer Basophils
These leukocytes are agranulocytes - Answer Monocytes, Lymphocytes (T and B cells)
Granulocytes that contain toxins that kill parasites, flukes and tapeworms - Answer
Eosinophils
What chemical circulating in the blood causes fever?
,A. Histamine
B. Perforin
C. Pyrogen
D. Pyogen
E. Lactoferrin - Answer C. Pyrogen
Which on of the following is not an effect of complement activation?
A. Formation of an attack complex
B. Attraction of phagocytes and enhancement of phagocytosis
C. Lysis of the cell through cytoplasmic leakage
D. Increased blood vessel permeability
E. Degradation of mRNA, cessation of protein synthesis and apoptosis - Answer E.
Degradation of mRNA, cessation of protein synthesis and apoptosis
Complement marks pathogens for destruction by all of the following except
A. C3B receptors
B. Classical pathway
C. Alternate pathway
D. TLR
E. MAC - Answer D. TLR
Digests the cell wall of gram-positive bacteria - Answer Lysozyme
An exogenous example would be a toxin - Answer Pyrogen
Elicits chemotaxis of immune cells - Answer Chemokine
Cause of complement mediated cell lysis - Answer Membrane attack complex
Ensnared pathogens are trapped in DNA, with degradative enzymes and peptides - Answer
Neutrophil extracellular trap
Which of the following is not an antigen?
A. Capsomere
B. Haptens
, C. Flagella proteins
D. Components of bacterial capsules
E. Pilus proteins - Answer B. Haptens
The ______________ antibody class is referred to as the maternal antibody
A. IgM
B. IgE
C. IgG
D. IgA
E. IgD - Answer C. IgG
Which one of the following is not an effect of complement activation?
A. Formation of a membrane attack complex
B. Attraction of phagocytes
C. Lysis of the cell through cytoplasmic leakage
D. Enhanced T-lymphocyte activity through thymus gland interaction
E. Production of C3b opsonin - Answer D. Enhanced T-lymphocyte activity through thymus
gland interaction
Which one of the following does not apply to plasma cells?
A. The are derived from B cells
B. They are effector B cells
C. They actively produce cytokines
D. They live for four to five days
E. They are large, highly complex cells - Answer C. They actively produce cytokines
The portion of the immunoglobulin molecule that contains the antigen binding site can be
described as all of the following except the
A. Fab fragment
B. Fc fragment
C. variable region
D. light chain
E. portion responsible for cross-linking - Answer B. Fc fragment
What accounts for the great amount of diversity in antibodies?