Complete Test Bank
Berne & Levy Physiology, 8th Edition
By Bruce M. Koeppen, Bruce A. Stanton, Julianne M. Hall, Agnieszka Swiatecka-Urban
(All Chapters, Latest Edition)
, Table of Contents
Section 1: Cellular Physiology, 1
1. Principles of Cell and Membrane Function, 2
2. Homeostasis: Volume and Composition of Body Fluid Compartments, 17
3. Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression, 34
Section 2: Neurophysiology, 49
4. The Nervous System: Introduction to Cells and Systems, 50
5. Generation and Conduction of Action Potentials, 63
6. Synaptic Transmission, 82
7. The Somatosensory System, 106
8. The Special Senses, 124
9. Organization of Motor Function, 158
10. Integrative Functions of the Nervous System, 204
11. The Autonomic Nervous System and Its Central Control, 222
Section 3: Muscle Physiology, 237
12. Skeletal Muscle Physiology, 238
13. Cardiac Muscle, 265
14. Smooth Muscle, 277
Section 4: Cardiovascular Physiology, 298
15. Overview of Circulation, 299
16. Elements of Cardiac Function, 302
17. Properties of the Vasculature, 342
18. Regulation of the Heart and Vasculature, 383
19. Integrated Control of the Cardiovascular System, 407
Section 5: Respiratory Physiology, 430
20. Introduction to the Respiratory System, 431
21. Static Lung and Chest Wall Mechanics, 444
22. Dynamic Lung and Chest Wall Mechanics, 453
23. Ventilation, Perfusion, and Ventilation/Perfusion Relationships, 463
24. Oxygen and Carbon Dioxide Transport, 477
25. Control of Respiration, 486
26. Host Defense and Metabolism in the Lung, 495
Section 6: Gastrointestinal Physiology, 506
27. Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract, 507
28. The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal, 516
29. The Gastric Phase of the Integrated Response to a Meal, 525
30. The Small Intestinal Phase of the Integrated Response to a Meal, 537
31. The Colonic Phase of the Integrated Response to a Meal, 554
32. Transport and Metabolic Functions of the Liver, 563
Section 7: Renal Physiology, 575
33. Elements of Renal Function, 576
34. Solute and Water Transport Along the Nephron: Tubular Function, 597
35. Control of Body Fluid Osmolality and Volume, 616
36. Potassium, Calcium, and Phosphate Homeostasis, 639
37. Role of the Kidneys in the Regulation of Acid-Base Balance, 661
Section 8: Endocrine Physiology, 676
38. Introduction to the Endocrine System, 677
39. Hormonal Regulation of Energy Metabolism, 689
40. Hormonal Regulation of Calcium and Phosphate Metabolism, 713
41. The Hypothalamus and Pituitary Gland, 723
42. The Thyroid Gland, 743
43. The Adrenal Gland, 756
44. The Male and Female Reproductive Systems, 776
, Chapter 1. Principles of Cell and Membrane Function,
Multiple Choice
1. The subcellular structure that degrades proteins is called the:
A. Tight junction
B. Mitochondria
C. Lysosome
D. Plasma membrane
E. Ribosome
Answer: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
data are obtained:
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
markedly reduced. According to this information, which of the followingmechanisms is
probably responsible for the transport of the amino acid into the cell?
A. Passive diffusion through the lipid bilayer
B. Uniporter
C. Transport ATPase
D. Na+ symporter
E. Na+ antiporter
Answer: D
3. A membrane permeable by only Na+ separates two compartments containing
Na2SO4,shown as follows:
Electrodes are placed in both compartments, and a voltage is applied (that of compartment A is
held at 0 mV). What voltage applied to compartment B would resultin no net movement of Na+
across the membrane separating the compartments?
, A. –60 mV
B. –30 mV
C. 0 mV
D. +30 mV
E. +60 mV
Answer: E
The resting membrane potentN ial oRfa I is –B
4.
U S ceNl lGT 85.C
mV. The intracellular and extracellular
concentrations of several ions are indicated in the following table, as is the calculated
Nernst equilibrium potential (Ei) for each of these ions:
Ion Concentration Concentration Ei
Inside Cell Outside Cell
Na+ 12 mEq/L 145 mEq/L 66 mV
K+ 150 mEq/L 4 mEq/L –96 mV
Cl– 30 mEq/L 105 mEq/L –33 mV
Ca++ 0.0001 mmol/dL 1 mmol/dL 122 mV
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
membrane is the greatest for which ion?
A. Na+
B. K+
C. Cl–
D. Ca++
Answer
:B
5. A cell contains the following membrane transporters:
Na+ channelK+ channel
Na+,K+-ATPase
The resting membrane voltage of the cell is –80 mV, and the intracellular and
extracellular ion concentrations are as follows:
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L 145 mEq/L
K+ 120 mEq/L 4 mEq/L
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug
on the following parameters?
Intracellular [Na+] Intracellular [K+] Cell Volume Membrane Voltage
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
D. Decrease Increase Decrease Hyperpolarize
Berne & Levy Physiology, 8th Edition
By Bruce M. Koeppen, Bruce A. Stanton, Julianne M. Hall, Agnieszka Swiatecka-Urban
(All Chapters, Latest Edition)
, Table of Contents
Section 1: Cellular Physiology, 1
1. Principles of Cell and Membrane Function, 2
2. Homeostasis: Volume and Composition of Body Fluid Compartments, 17
3. Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression, 34
Section 2: Neurophysiology, 49
4. The Nervous System: Introduction to Cells and Systems, 50
5. Generation and Conduction of Action Potentials, 63
6. Synaptic Transmission, 82
7. The Somatosensory System, 106
8. The Special Senses, 124
9. Organization of Motor Function, 158
10. Integrative Functions of the Nervous System, 204
11. The Autonomic Nervous System and Its Central Control, 222
Section 3: Muscle Physiology, 237
12. Skeletal Muscle Physiology, 238
13. Cardiac Muscle, 265
14. Smooth Muscle, 277
Section 4: Cardiovascular Physiology, 298
15. Overview of Circulation, 299
16. Elements of Cardiac Function, 302
17. Properties of the Vasculature, 342
18. Regulation of the Heart and Vasculature, 383
19. Integrated Control of the Cardiovascular System, 407
Section 5: Respiratory Physiology, 430
20. Introduction to the Respiratory System, 431
21. Static Lung and Chest Wall Mechanics, 444
22. Dynamic Lung and Chest Wall Mechanics, 453
23. Ventilation, Perfusion, and Ventilation/Perfusion Relationships, 463
24. Oxygen and Carbon Dioxide Transport, 477
25. Control of Respiration, 486
26. Host Defense and Metabolism in the Lung, 495
Section 6: Gastrointestinal Physiology, 506
27. Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract, 507
28. The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal, 516
29. The Gastric Phase of the Integrated Response to a Meal, 525
30. The Small Intestinal Phase of the Integrated Response to a Meal, 537
31. The Colonic Phase of the Integrated Response to a Meal, 554
32. Transport and Metabolic Functions of the Liver, 563
Section 7: Renal Physiology, 575
33. Elements of Renal Function, 576
34. Solute and Water Transport Along the Nephron: Tubular Function, 597
35. Control of Body Fluid Osmolality and Volume, 616
36. Potassium, Calcium, and Phosphate Homeostasis, 639
37. Role of the Kidneys in the Regulation of Acid-Base Balance, 661
Section 8: Endocrine Physiology, 676
38. Introduction to the Endocrine System, 677
39. Hormonal Regulation of Energy Metabolism, 689
40. Hormonal Regulation of Calcium and Phosphate Metabolism, 713
41. The Hypothalamus and Pituitary Gland, 723
42. The Thyroid Gland, 743
43. The Adrenal Gland, 756
44. The Male and Female Reproductive Systems, 776
, Chapter 1. Principles of Cell and Membrane Function,
Multiple Choice
1. The subcellular structure that degrades proteins is called the:
A. Tight junction
B. Mitochondria
C. Lysosome
D. Plasma membrane
E. Ribosome
Answer: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
data are obtained:
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
markedly reduced. According to this information, which of the followingmechanisms is
probably responsible for the transport of the amino acid into the cell?
A. Passive diffusion through the lipid bilayer
B. Uniporter
C. Transport ATPase
D. Na+ symporter
E. Na+ antiporter
Answer: D
3. A membrane permeable by only Na+ separates two compartments containing
Na2SO4,shown as follows:
Electrodes are placed in both compartments, and a voltage is applied (that of compartment A is
held at 0 mV). What voltage applied to compartment B would resultin no net movement of Na+
across the membrane separating the compartments?
, A. –60 mV
B. –30 mV
C. 0 mV
D. +30 mV
E. +60 mV
Answer: E
The resting membrane potentN ial oRfa I is –B
4.
U S ceNl lGT 85.C
mV. The intracellular and extracellular
concentrations of several ions are indicated in the following table, as is the calculated
Nernst equilibrium potential (Ei) for each of these ions:
Ion Concentration Concentration Ei
Inside Cell Outside Cell
Na+ 12 mEq/L 145 mEq/L 66 mV
K+ 150 mEq/L 4 mEq/L –96 mV
Cl– 30 mEq/L 105 mEq/L –33 mV
Ca++ 0.0001 mmol/dL 1 mmol/dL 122 mV
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
membrane is the greatest for which ion?
A. Na+
B. K+
C. Cl–
D. Ca++
Answer
:B
5. A cell contains the following membrane transporters:
Na+ channelK+ channel
Na+,K+-ATPase
The resting membrane voltage of the cell is –80 mV, and the intracellular and
extracellular ion concentrations are as follows:
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L 145 mEq/L
K+ 120 mEq/L 4 mEq/L
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug
on the following parameters?
Intracellular [Na+] Intracellular [K+] Cell Volume Membrane Voltage
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
D. Decrease Increase Decrease Hyperpolarize
