WITH VERIFIED ANSWERS
Chlorpromazine (Thorazine), Fluphenazine, Haloperidol, Perphazine, Loxapine
Neuroleptics (Typical Antipsychotics, FGAs)
Clozapine (Clozaril), Olanzapine, Quetiapine, Ziprasidone, Risperidone,
Paliperidone
Atypical Antipsychotics (SGAs)
Aripiprazole (Abilify)
Atypical antipsychotic. TGA.
Valproate (Divalproex), Carbamazepine, Lamotrigine
Anticonvulsants
Lithium Carbonate
Mood stabilizer, antimanic, antidepressive
For bipolar disorder: affects storage, relsease, and reuptake of neurotransmitters
Adverse reactions/side effects: nausea, fatigue, hand tremors, weight gain, hypothyroid,
renal impairment
Toxicity: diarrhea, muscle weakness, unsteady gait, slurred speech
Nursing considerations: maintain adequate serum levels (0.6-1.2), toxicity over 1.5,
check renal, cardiac, thyroid levels, Na, do not use with diuretics
Education: Hydrate, take with food, taper off, may gain 5 lbs of water weight within first
week.
, EPS can be treated with
Anticholinergics: benztropine (Cogentin) or diphenhydramine (Benadryl)
EPS can develop into....
tardive dyskinesia (irregular, jerky movements), which is a permanent condition
Acute dystonia
Facial grimacing
Involuntary upward eye movement
Muscle Spasms of tongue, face, neck
Acute dystonia treatment
Treat with benztropine (Cogentin) or diphenhydramine (benadryl)
Akathesia
inability to remain still; motor restlessness and anxiety; high risk for suicidality; patients
may complain of feeling like their are bugs under their skin.
NMS (neuroleptic malignant syndrome)
A life-threatening drug reaction characterized by fever, change in BP and pulse,
sweating, seizures, and change in LOC
NMS treatment
Dantrolene: MUSCLE RELAXTION
D2 agonists (e.g., bromocriptine)