ANTICOAGULATION NEWLY UPDATED COLLECTION OF EXAM
QUESTIONS AND VERIFIED ANSWERS DESIGNED TO GUARANTEE
YOUR SUCCESS
JK is a 62 yo F with chronic UTI. Several times a year, she receives a
prescription for Bactrim. JK comes to the pharmacy today with a
prescription for warfarin with 11 refills. The pharmacist should
emphasize the following counseling to this pt: SATA - ANSWER She will
need more frequent INR monitoring when starting or stopping Bactrim
The drug interaction between warfarin and Bactrim may lead to
significant bleeding
NOT:
She should stop taking warfarin while she is taking Bactrim to treat her
UTI
Warfarin can cause the Bactrim to be ineffective in treating the UTI
When taking both warfarin and Bactrim, separate doses by 4 hours to
decrease the risk of a drug interaction.
A 42 year old female presents to the hospital with a DVT and is started
on enoxaparin by the overnight physician. The next day, the medical
resident asks the pharmacist why LMWH products are often preferred to
UFH. What are the advantages to the use of LMWH over UFH? SATA -
ANSWER LMWHs have a more consistent anticoag response.
LMWHs do not require lab monitoring for efficacy in most pts.
LMWHs are more cost-effective than heparin.
NOT: LMWHs are easier to reverse in pts that experience sig bleeding
LMWHs are more efficacious than heparin in treating DVTs
MH is a 66 yo M with hypertension, renal disease, and degenerative joint
disease. In his younger years, MH was a football player and has lived
with the pain of a hip injury for many years. The physician orders
enoxaparin 30 mg SC BID for DVT prophylaxis. Choose the correct
statement: - ANSWER The dose should be 30 mg SC daily
, * if CrCl is < 30 the dose is reduced to 30 mg SC once daily
The pharmacist receives a prescription for dalteparin. What type of
medication is dalteparin? - ANSWER LMWH
SN is a 52 year old female being seen in the Anticoagulation clinic
Which of Sn's lab results suggests that she could experience an altered
response to warfarin?
hypoalbuminemia
Hypokalemia
Hyponatremia
Increased BUN/SCr
Hyperglycemia - ANSWER Hypoalbuminemia - warfarin is highly protein-
bound
* Pts with low albumin (possibly malnourished) will have more free drug
in their system and be at an increased risk of bleeding - generally
require a lower dose, monitor carefully
A pt is being started on Pradaxa. Choose the correct statement
regarding Pradaxa. - ANSWER Once a bottle of Pradaxa is opened, the
capsules must be used within 120 days
* 60-count bottles of Pradaxa expire 4 months after opening the bottle
A 25 year-old female is receiving warfarin for a DVT. Her counseling
should include the following: - ANSWER Warfarin is unsafe in pregnancy
and should be avoided
* C/I in pregnancy (Category X) unless pt has a mechanical heart valve
(Category D)
Select the correct dosing recommendation for apixaban for a pt with a
DVT: - ANSWER 10 mg PO BID x7 days then 5 mg PO BID
Which lab value must be carefully monitored when a pt is receiving
heparin? - ANSWER Platelets - serious adverse effect associated with
heparin therapy is HIT - sig drop in platelets caused by an immune
response against platelets
Which of the following lab parameters need to be monitored during
heparin therapy? SATA - ANSWER aPTT
Hematocrit
Hemoglobin
Platelets
QUESTIONS AND VERIFIED ANSWERS DESIGNED TO GUARANTEE
YOUR SUCCESS
JK is a 62 yo F with chronic UTI. Several times a year, she receives a
prescription for Bactrim. JK comes to the pharmacy today with a
prescription for warfarin with 11 refills. The pharmacist should
emphasize the following counseling to this pt: SATA - ANSWER She will
need more frequent INR monitoring when starting or stopping Bactrim
The drug interaction between warfarin and Bactrim may lead to
significant bleeding
NOT:
She should stop taking warfarin while she is taking Bactrim to treat her
UTI
Warfarin can cause the Bactrim to be ineffective in treating the UTI
When taking both warfarin and Bactrim, separate doses by 4 hours to
decrease the risk of a drug interaction.
A 42 year old female presents to the hospital with a DVT and is started
on enoxaparin by the overnight physician. The next day, the medical
resident asks the pharmacist why LMWH products are often preferred to
UFH. What are the advantages to the use of LMWH over UFH? SATA -
ANSWER LMWHs have a more consistent anticoag response.
LMWHs do not require lab monitoring for efficacy in most pts.
LMWHs are more cost-effective than heparin.
NOT: LMWHs are easier to reverse in pts that experience sig bleeding
LMWHs are more efficacious than heparin in treating DVTs
MH is a 66 yo M with hypertension, renal disease, and degenerative joint
disease. In his younger years, MH was a football player and has lived
with the pain of a hip injury for many years. The physician orders
enoxaparin 30 mg SC BID for DVT prophylaxis. Choose the correct
statement: - ANSWER The dose should be 30 mg SC daily
, * if CrCl is < 30 the dose is reduced to 30 mg SC once daily
The pharmacist receives a prescription for dalteparin. What type of
medication is dalteparin? - ANSWER LMWH
SN is a 52 year old female being seen in the Anticoagulation clinic
Which of Sn's lab results suggests that she could experience an altered
response to warfarin?
hypoalbuminemia
Hypokalemia
Hyponatremia
Increased BUN/SCr
Hyperglycemia - ANSWER Hypoalbuminemia - warfarin is highly protein-
bound
* Pts with low albumin (possibly malnourished) will have more free drug
in their system and be at an increased risk of bleeding - generally
require a lower dose, monitor carefully
A pt is being started on Pradaxa. Choose the correct statement
regarding Pradaxa. - ANSWER Once a bottle of Pradaxa is opened, the
capsules must be used within 120 days
* 60-count bottles of Pradaxa expire 4 months after opening the bottle
A 25 year-old female is receiving warfarin for a DVT. Her counseling
should include the following: - ANSWER Warfarin is unsafe in pregnancy
and should be avoided
* C/I in pregnancy (Category X) unless pt has a mechanical heart valve
(Category D)
Select the correct dosing recommendation for apixaban for a pt with a
DVT: - ANSWER 10 mg PO BID x7 days then 5 mg PO BID
Which lab value must be carefully monitored when a pt is receiving
heparin? - ANSWER Platelets - serious adverse effect associated with
heparin therapy is HIT - sig drop in platelets caused by an immune
response against platelets
Which of the following lab parameters need to be monitored during
heparin therapy? SATA - ANSWER aPTT
Hematocrit
Hemoglobin
Platelets
