Women’s Health NP End-of-Course
Practice Exam – 150-Item Test Bank
Answers And Rationale Included
2025/2026
1. A 32-year-old woman presents for contraception counseling. She
has a history of migraines with aura. Which contraceptive method is
safest for her?
A. Combined oral contraceptives
B. Progestin-only pills
C. Transdermal contraceptive patch
D. Vaginal ring
Rationale: Women with migraines with aura are at increased risk of
stroke with estrogen-containing contraceptives; progestin-only
methods are safer.
2. Which of the following is the most common cause of abnormal
uterine bleeding in reproductive-aged women?
A. Endometrial cancer
B. Polycystic ovarian syndrome
C. Anovulation
D. Fibroids
Rationale: Anovulation is the most common cause of abnormal
uterine bleeding due to hormonal imbalance, especially in younger
women.
,3. A patient presents with pelvic pain, dysmenorrhea, and infertility.
Which diagnosis is most likely?
A. Pelvic inflammatory disease
B. Endometriosis
C. Endometriosis
D. Ovarian cyst
Rationale: Endometriosis typically presents with chronic pelvic pain,
dysmenorrhea, dyspareunia, and infertility.
4. Which screening is recommended for women aged 21–29?
A. Pap smear every 5 years
B. Pap smear every 3 years
C. HPV testing alone every 3 years
D. No screening
Rationale: Guidelines recommend Pap smear every 3 years for women
aged 21–29, without HPV co-testing.
5. The first-line treatment for bacterial vaginosis is:
A. Clindamycin oral
B. Metronidazole vaginal gel
C. Metronidazole oral
D. Fluconazole
Rationale: Oral metronidazole 500 mg twice daily for 7 days is first-
line therapy for BV.
,6. A 45-year-old woman presents with vasomotor symptoms and hot
flashes. Which therapy is most effective?
A. Non-hormonal therapy only
B. Systemic hormone replacement therapy
C. Topical estrogen cream
D. Lifestyle modification
Rationale: Systemic hormone replacement therapy is the most
effective treatment for moderate to severe vasomotor symptoms.
7. Which of the following is a risk factor for endometrial cancer?
A. Multiparity
B. Obesity
C. Use of combined oral contraceptives
D. Smoking
Rationale: Obesity increases estrogen levels, leading to endometrial
hyperplasia and cancer risk.
8. A patient presents with amenorrhea for 6 months. Her pregnancy
test is negative. Next best step:
A. Start oral contraceptives
B. Check serum FSH, LH, and prolactin
C. Pelvic ultrasound
D. Endometrial biopsy
Rationale: Hormonal evaluation (FSH, LH, prolactin) helps
differentiate causes of secondary amenorrhea.
, 9. Which vaccine is recommended for all adults through age 26 if not
previously vaccinated?
A. Influenza
B. HPV
C. Tdap
D. MMR
Rationale: HPV vaccination is recommended for all adults through age
26 to prevent cervical and other HPV-related cancers.
10. The most common pathogen in acute uncomplicated cystitis in
women is:
A. Staphylococcus saprophyticus
B. Escherichia coli
C. Klebsiella pneumoniae
D. Enterococcus faecalis
Rationale: E. coli accounts for 75–95% of cases of uncomplicated
urinary tract infections in women.
11. Which of the following is true regarding menopause?
A. Menopause occurs at a mean age of 50–52 years
B. Perimenopause can start 4–8 years before final menstrual period
C. Hot flashes only occur after menopause
D. Estrogen levels rise after menopause
Rationale: Perimenopause can begin several years before the final
menstrual period, with fluctuating estrogen levels.
Practice Exam – 150-Item Test Bank
Answers And Rationale Included
2025/2026
1. A 32-year-old woman presents for contraception counseling. She
has a history of migraines with aura. Which contraceptive method is
safest for her?
A. Combined oral contraceptives
B. Progestin-only pills
C. Transdermal contraceptive patch
D. Vaginal ring
Rationale: Women with migraines with aura are at increased risk of
stroke with estrogen-containing contraceptives; progestin-only
methods are safer.
2. Which of the following is the most common cause of abnormal
uterine bleeding in reproductive-aged women?
A. Endometrial cancer
B. Polycystic ovarian syndrome
C. Anovulation
D. Fibroids
Rationale: Anovulation is the most common cause of abnormal
uterine bleeding due to hormonal imbalance, especially in younger
women.
,3. A patient presents with pelvic pain, dysmenorrhea, and infertility.
Which diagnosis is most likely?
A. Pelvic inflammatory disease
B. Endometriosis
C. Endometriosis
D. Ovarian cyst
Rationale: Endometriosis typically presents with chronic pelvic pain,
dysmenorrhea, dyspareunia, and infertility.
4. Which screening is recommended for women aged 21–29?
A. Pap smear every 5 years
B. Pap smear every 3 years
C. HPV testing alone every 3 years
D. No screening
Rationale: Guidelines recommend Pap smear every 3 years for women
aged 21–29, without HPV co-testing.
5. The first-line treatment for bacterial vaginosis is:
A. Clindamycin oral
B. Metronidazole vaginal gel
C. Metronidazole oral
D. Fluconazole
Rationale: Oral metronidazole 500 mg twice daily for 7 days is first-
line therapy for BV.
,6. A 45-year-old woman presents with vasomotor symptoms and hot
flashes. Which therapy is most effective?
A. Non-hormonal therapy only
B. Systemic hormone replacement therapy
C. Topical estrogen cream
D. Lifestyle modification
Rationale: Systemic hormone replacement therapy is the most
effective treatment for moderate to severe vasomotor symptoms.
7. Which of the following is a risk factor for endometrial cancer?
A. Multiparity
B. Obesity
C. Use of combined oral contraceptives
D. Smoking
Rationale: Obesity increases estrogen levels, leading to endometrial
hyperplasia and cancer risk.
8. A patient presents with amenorrhea for 6 months. Her pregnancy
test is negative. Next best step:
A. Start oral contraceptives
B. Check serum FSH, LH, and prolactin
C. Pelvic ultrasound
D. Endometrial biopsy
Rationale: Hormonal evaluation (FSH, LH, prolactin) helps
differentiate causes of secondary amenorrhea.
, 9. Which vaccine is recommended for all adults through age 26 if not
previously vaccinated?
A. Influenza
B. HPV
C. Tdap
D. MMR
Rationale: HPV vaccination is recommended for all adults through age
26 to prevent cervical and other HPV-related cancers.
10. The most common pathogen in acute uncomplicated cystitis in
women is:
A. Staphylococcus saprophyticus
B. Escherichia coli
C. Klebsiella pneumoniae
D. Enterococcus faecalis
Rationale: E. coli accounts for 75–95% of cases of uncomplicated
urinary tract infections in women.
11. Which of the following is true regarding menopause?
A. Menopause occurs at a mean age of 50–52 years
B. Perimenopause can start 4–8 years before final menstrual period
C. Hot flashes only occur after menopause
D. Estrogen levels rise after menopause
Rationale: Perimenopause can begin several years before the final
menstrual period, with fluctuating estrogen levels.
