Page 1 of 99
2025/2026 ANCC AGACNP CERTIFICATION EXAM
BANK WITH ALL COMPLETE CURRENT QUESTIONS
AND DETAILED CORRECT (VERIFIED) ANSWERS
FOR GUARANTEED PASS/TOP-RATED A+.
ANCC AGACNP
Ace your ANCC Adult-Gerontology Acute Care Nurse
Practitioner (AGACNP) certification exam with this
comprehensive guide, designed to master complex clinical
presentations, emergency interventions, and evidence-based
protocols for adult and geriatric patients. This resource delivers
high-acuity scenario questions covering advanced
pathophysiology, pharmacotherapeutics, and systems-level
management.
What does a loss of y descent on central venous catheter
waveform represent? ...... ANSWER ....... Cardiac
tamponade because there is equalization of pressures
between the atria and ventricles
How do you tell gastric ulcer from duodenal? ...... ANSWER
....... Gastric is not relieved by food
Most common with chronic NSAID use
Epigastric pain 1-3 hours after eating
, Page 2 of 99
What is first line inotrope for septic shock? ...... ANSWER
....... Epinephrine
Increased diastolic blood pressure through systemic arterial
vasoconstriction and also increases preload by
venoconstriction
What risk do you worry about with high concentration of
inspired O2 through the ventilator? ...... ANSWER .......
Pulmonary fibrosis
What are the contraindications for thrombolysis? ......
ANSWER ....... Absolute: hx of brain neoplasm, recent
intracranial surgery or trauma < 2 mos, active of recent
internal bleeding < 6 mos
Relative: nonhem stroke, bleeding disorders,
uncontrolled hypertension, recent surgery within 10 days
What PFT is hallmark for interstitial lung disease? ......
ANSWER ....... Decreased DLCO as a result of damage to
alveolar capillaries
What lung findings are consistent with asbestosis? ......
ANSWER ....... Pleural plaques, pleural effusions,
reticulonodular infiltrates
, Page 3 of 99
What PFT differentiates emphysema from chronic
bronchitis? ...... ANSWER ....... DLCO will be decreased
in emphysema, which is characterized destruction and
dilation of the alveolar walls
What is: mild dyspnea, low grade fevers, night sweats,
muscle and joint pain, chronic cough, rash on lower
extremities and now in arms ...... ANSWER .......
Sarcoidosis - good prognosis with spontaneous
remission
What does a helical CT diagnose? ...... ANSWER ....... PE
How do you confirm lung cancer? ...... ANSWER .......
Biopsy
What benefit do you get from interrupting sedation daily for
people on mechanical ventilation? ...... ANSWER ....... -
decreased duration of ventilation
- decreased ICU stay
- decreased 1 year mortality
, Page 4 of 99
What does induced paralysis in ARDS do? ...... ANSWER
....... Increase oxygenation
What are the causes of anion gap metabolic acidosis? ......
ANSWER ....... MUD PILES CAT
Methanol/Metformin
Uremia
DKA
Propylene Glycol
INH/Iron
Lactic Acidosis
Ethylene Glycol
Salicylates (Late)
Cyanide
Alcohol/Acids
Theophylline
If a patient has the "worst headache of my life" that comes
on suddenly, what is the differential and plan ...... ANSWER
....... Subarachnoid hemorrhage
CT
2025/2026 ANCC AGACNP CERTIFICATION EXAM
BANK WITH ALL COMPLETE CURRENT QUESTIONS
AND DETAILED CORRECT (VERIFIED) ANSWERS
FOR GUARANTEED PASS/TOP-RATED A+.
ANCC AGACNP
Ace your ANCC Adult-Gerontology Acute Care Nurse
Practitioner (AGACNP) certification exam with this
comprehensive guide, designed to master complex clinical
presentations, emergency interventions, and evidence-based
protocols for adult and geriatric patients. This resource delivers
high-acuity scenario questions covering advanced
pathophysiology, pharmacotherapeutics, and systems-level
management.
What does a loss of y descent on central venous catheter
waveform represent? ...... ANSWER ....... Cardiac
tamponade because there is equalization of pressures
between the atria and ventricles
How do you tell gastric ulcer from duodenal? ...... ANSWER
....... Gastric is not relieved by food
Most common with chronic NSAID use
Epigastric pain 1-3 hours after eating
, Page 2 of 99
What is first line inotrope for septic shock? ...... ANSWER
....... Epinephrine
Increased diastolic blood pressure through systemic arterial
vasoconstriction and also increases preload by
venoconstriction
What risk do you worry about with high concentration of
inspired O2 through the ventilator? ...... ANSWER .......
Pulmonary fibrosis
What are the contraindications for thrombolysis? ......
ANSWER ....... Absolute: hx of brain neoplasm, recent
intracranial surgery or trauma < 2 mos, active of recent
internal bleeding < 6 mos
Relative: nonhem stroke, bleeding disorders,
uncontrolled hypertension, recent surgery within 10 days
What PFT is hallmark for interstitial lung disease? ......
ANSWER ....... Decreased DLCO as a result of damage to
alveolar capillaries
What lung findings are consistent with asbestosis? ......
ANSWER ....... Pleural plaques, pleural effusions,
reticulonodular infiltrates
, Page 3 of 99
What PFT differentiates emphysema from chronic
bronchitis? ...... ANSWER ....... DLCO will be decreased
in emphysema, which is characterized destruction and
dilation of the alveolar walls
What is: mild dyspnea, low grade fevers, night sweats,
muscle and joint pain, chronic cough, rash on lower
extremities and now in arms ...... ANSWER .......
Sarcoidosis - good prognosis with spontaneous
remission
What does a helical CT diagnose? ...... ANSWER ....... PE
How do you confirm lung cancer? ...... ANSWER .......
Biopsy
What benefit do you get from interrupting sedation daily for
people on mechanical ventilation? ...... ANSWER ....... -
decreased duration of ventilation
- decreased ICU stay
- decreased 1 year mortality
, Page 4 of 99
What does induced paralysis in ARDS do? ...... ANSWER
....... Increase oxygenation
What are the causes of anion gap metabolic acidosis? ......
ANSWER ....... MUD PILES CAT
Methanol/Metformin
Uremia
DKA
Propylene Glycol
INH/Iron
Lactic Acidosis
Ethylene Glycol
Salicylates (Late)
Cyanide
Alcohol/Acids
Theophylline
If a patient has the "worst headache of my life" that comes
on suddenly, what is the differential and plan ...... ANSWER
....... Subarachnoid hemorrhage
CT
