NUR 328 Exam 3 Questions with
Correct Answers 100% Pass
basic diuretics MOAs - CORRECT ANSWER-block Na+ and Cl- reabsorption,
increase urine output
three basic renal processes - CORRECT ANSWER-filtration, reabsorption, active
tubular secretion
What can be reabsorbed in the nephron? - CORRECT ANSWER-99% of water,
nutrients, and electrolytes, and any laid soluble drugs are reabsorbed back in to the
blood stream .
Where does tubular secretion occur? - CORRECT ANSWER-The proximal
convoluted tubule
What is actively secreted in the PCT? - CORRECT ANSWER-Organic acid and
bases, drugs are secreted from blood to urine
Sites of Action of Diuretics - CORRECT ANSWER-PCT(65%), ascending
LofH(20%), and DCT(10% early, 5-1% in distal)
Classifications of Diuretics - CORRECT ANSWER-Loop, Thiazides, K+ sparing,
Osmotic, Carbonic Anhydrase inhibitors
,Loop Diuretics - CORRECT ANSWER-furosemide, bumetanide, torsemide,
ethacrynic acid
Saying for Loop Diuretics - CORRECT ANSWER-Furry Bums Tour Ecstasy
Furosemide (Lasix) MOA - CORRECT ANSWER-Block Na+/Cl- reabsorption in
the ascending LofH, which causes increased H20 excretion(urine)
Therapeutic Use of Furosemide - CORRECT ANSWER-Pulmonary , hepatic,
cardiac, and renal edema, HTN, low renal blood flow/GFR(kidney failure)
Adverse effects of Furosemide - CORRECT ANSWER-Hypo(Na, Cl, K, Mg,
Ca+), hyperglycemia, hyperuricemia, hypotension, ototoxicity(high doses and is
reversible), lipid change low HDL.
What must you monitor with Furosemide? - CORRECT ANSWER-Blood
pressure, urine output, and weight
Drug interactions of Furosemide - CORRECT ANSWER-Digoxin, ototoxic drugs,
K+ sparring, lithium, antihypertensive drugs, NSAIDSf
Thiazides - CORRECT ANSWER-Hydrochlorothiazide, Chlorothiazide,
methyclothiazide, chlorthalidone, Indapamide, metolazone
Saying for Thiazide Drugs - CORRECT ANSWER-HideYour, Methy, 2Children,
Inda, Me
MOA of thiazides - CORRECT ANSWER-Blocks NA/Cl reabsorption in the
early DCT(10%=lower diuresis than Loop Diuretics)
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,Are thiazides effective with GFR? - CORRECT ANSWER-No, they can't be used
for patients with kidney damage
TU of Thiazides and related diuretics - CORRECT ANSWER-Essential
HTN(predisposed, or overweight) AND edema
Adverse Effects of Thiazides - CORRECT ANSWER-HYPO(Na, CL, K, Mg, ),
HypoVOLemia, HYPER:glycemia, uricemia, and calcemia
Increases Bad Cholesterol and TG
Drug Interactions of Thiazides - CORRECT ANSWER-Digoxin, antihypertensive
drugs, lithium toxicity, NSAIDS, CAN be used with Ototoxic drugs
Potassium Sparing Drugs: Aldosterone Antagonist - CORRECT ANSWER-
Spironolactone
Potassium Sparing Drugs: Non-Aldosterone Antagonist - CORRECT ANSWER-
Triamterene, Amiloride
How to remember K+ Sparing Alodsterone Antagonist - CORRECT ANSWER-
SPARING and SPIRO
Saying for Non-Aldosterone Antagonists - CORRECT ANSWER-Titties
AmIRight
MOA: Spironolactone - CORRECT ANSWER-Indirect K+ retention and increase
sodium excretion by blocking aldosterone action in distal DCT. Late onset due to
only affecting new transport proteins
, Therapeutic Use of Spironolactone - CORRECT ANSWER-HTN, edemas state,
HF, hyperaldosteronism, PMS, PCOS, Acne
Adverse Effects of Sprinolactone - CORRECT ANSWER-HYPER K+, Mimic
other sex hormone, gynomastia
Drug Interactions Sprinolactone - CORRECT ANSWER-Can counteract K+ loss
of Loop and Thiazides, and other drugs increasing K+ levels(ACEI, ARBS, and
DRI), Potassium supplements, and salt substitutes
Triamterene MOA - CORRECT ANSWER-DIRECT disruption of Na/K
exchange at DCT. Effects happen immediately. Causes low sodium reabsorption
and decreased K+ secretion
Therapeutic Use of Non-aldosterone K+ sparing - CORRECT ANSWER-HTN
and Edema
Adverse effects triamterene - CORRECT ANSWER-Hyperkalemia, leg cramps,
NA/V, dizziness
Osmotic Diuretics - CORRECT ANSWER-Mannitol
Mannitol MOA - CORRECT ANSWER-Promotes diuresis by creating osmotic
force of lumen, must be given IV, no effect on patient sugar levels
Therapeutic Use of Mannitol - CORRECT ANSWER-Prophylaxisis of renal
failure, ICP, IOP
Adverse effects of Mannitol - CORRECT ANSWER-Edema
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Correct Answers 100% Pass
basic diuretics MOAs - CORRECT ANSWER-block Na+ and Cl- reabsorption,
increase urine output
three basic renal processes - CORRECT ANSWER-filtration, reabsorption, active
tubular secretion
What can be reabsorbed in the nephron? - CORRECT ANSWER-99% of water,
nutrients, and electrolytes, and any laid soluble drugs are reabsorbed back in to the
blood stream .
Where does tubular secretion occur? - CORRECT ANSWER-The proximal
convoluted tubule
What is actively secreted in the PCT? - CORRECT ANSWER-Organic acid and
bases, drugs are secreted from blood to urine
Sites of Action of Diuretics - CORRECT ANSWER-PCT(65%), ascending
LofH(20%), and DCT(10% early, 5-1% in distal)
Classifications of Diuretics - CORRECT ANSWER-Loop, Thiazides, K+ sparing,
Osmotic, Carbonic Anhydrase inhibitors
,Loop Diuretics - CORRECT ANSWER-furosemide, bumetanide, torsemide,
ethacrynic acid
Saying for Loop Diuretics - CORRECT ANSWER-Furry Bums Tour Ecstasy
Furosemide (Lasix) MOA - CORRECT ANSWER-Block Na+/Cl- reabsorption in
the ascending LofH, which causes increased H20 excretion(urine)
Therapeutic Use of Furosemide - CORRECT ANSWER-Pulmonary , hepatic,
cardiac, and renal edema, HTN, low renal blood flow/GFR(kidney failure)
Adverse effects of Furosemide - CORRECT ANSWER-Hypo(Na, Cl, K, Mg,
Ca+), hyperglycemia, hyperuricemia, hypotension, ototoxicity(high doses and is
reversible), lipid change low HDL.
What must you monitor with Furosemide? - CORRECT ANSWER-Blood
pressure, urine output, and weight
Drug interactions of Furosemide - CORRECT ANSWER-Digoxin, ototoxic drugs,
K+ sparring, lithium, antihypertensive drugs, NSAIDSf
Thiazides - CORRECT ANSWER-Hydrochlorothiazide, Chlorothiazide,
methyclothiazide, chlorthalidone, Indapamide, metolazone
Saying for Thiazide Drugs - CORRECT ANSWER-HideYour, Methy, 2Children,
Inda, Me
MOA of thiazides - CORRECT ANSWER-Blocks NA/Cl reabsorption in the
early DCT(10%=lower diuresis than Loop Diuretics)
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,Are thiazides effective with GFR? - CORRECT ANSWER-No, they can't be used
for patients with kidney damage
TU of Thiazides and related diuretics - CORRECT ANSWER-Essential
HTN(predisposed, or overweight) AND edema
Adverse Effects of Thiazides - CORRECT ANSWER-HYPO(Na, CL, K, Mg, ),
HypoVOLemia, HYPER:glycemia, uricemia, and calcemia
Increases Bad Cholesterol and TG
Drug Interactions of Thiazides - CORRECT ANSWER-Digoxin, antihypertensive
drugs, lithium toxicity, NSAIDS, CAN be used with Ototoxic drugs
Potassium Sparing Drugs: Aldosterone Antagonist - CORRECT ANSWER-
Spironolactone
Potassium Sparing Drugs: Non-Aldosterone Antagonist - CORRECT ANSWER-
Triamterene, Amiloride
How to remember K+ Sparing Alodsterone Antagonist - CORRECT ANSWER-
SPARING and SPIRO
Saying for Non-Aldosterone Antagonists - CORRECT ANSWER-Titties
AmIRight
MOA: Spironolactone - CORRECT ANSWER-Indirect K+ retention and increase
sodium excretion by blocking aldosterone action in distal DCT. Late onset due to
only affecting new transport proteins
, Therapeutic Use of Spironolactone - CORRECT ANSWER-HTN, edemas state,
HF, hyperaldosteronism, PMS, PCOS, Acne
Adverse Effects of Sprinolactone - CORRECT ANSWER-HYPER K+, Mimic
other sex hormone, gynomastia
Drug Interactions Sprinolactone - CORRECT ANSWER-Can counteract K+ loss
of Loop and Thiazides, and other drugs increasing K+ levels(ACEI, ARBS, and
DRI), Potassium supplements, and salt substitutes
Triamterene MOA - CORRECT ANSWER-DIRECT disruption of Na/K
exchange at DCT. Effects happen immediately. Causes low sodium reabsorption
and decreased K+ secretion
Therapeutic Use of Non-aldosterone K+ sparing - CORRECT ANSWER-HTN
and Edema
Adverse effects triamterene - CORRECT ANSWER-Hyperkalemia, leg cramps,
NA/V, dizziness
Osmotic Diuretics - CORRECT ANSWER-Mannitol
Mannitol MOA - CORRECT ANSWER-Promotes diuresis by creating osmotic
force of lumen, must be given IV, no effect on patient sugar levels
Therapeutic Use of Mannitol - CORRECT ANSWER-Prophylaxisis of renal
failure, ICP, IOP
Adverse effects of Mannitol - CORRECT ANSWER-Edema
COPYRIGHT ALL RIGHTS RESERVED ©️ 2025
