OCR A LEVEL CHEMISTRY (H432)
ORGANIC SYNTHESIS - SYNTHETIC
ROUTES STUDT GUIDE QUESTIONS
AND ANSWERS LATEST 2025
Haloalkane (R-X) → Nitrile (R-C≡N) - CORRECT ANSWER-KCN
(potassium cyanide) (or NaCN) in ethanol
Nucleophilic Substitution
Haloalkane (R-X) → Amine (R-NH₂) - CORRECT ANSWER-NH₃
(ammonia) in ethanol
Carboxylic acid (R-COOH) → Ester (R-COO-R') - CORRECT
ANSWER-Alcohol (R'-OH)
concentrated H₂SO₄ catalyst
, Esterification
Primary Alcohol (R-CH₂OH) → Aldehyde (R-CHO) - CORRECT
ANSWER-Distil with K₂Cr₂O₇/H₂SO₄ (acidified potassium dichromate)
Primary Alcohol (R-CH₂OH) → Carboxylic acid (R-COOH) - CORRECT
ANSWER-Reflux with K₂Cr₂O₇/H₂SO₄ (acidified potassium
dichromate)
Uses two molecules of oxidising agent ([O]), produces one molecule of
H₂O
Secondary Alcohol (R-CH(OH)-R') → Ketone (R-C(O)-R') - CORRECT
ANSWER-Reflux with K₂Cr₂O₇/H₂SO₄ (acidified potassium
dichromate)
Byproduct: H₂O
Alkane → Haloalkane (R-X) - CORRECT ANSWER-Halogen (X₂)
Ultraviolet light (UV)
Free radical substitution
ORGANIC SYNTHESIS - SYNTHETIC
ROUTES STUDT GUIDE QUESTIONS
AND ANSWERS LATEST 2025
Haloalkane (R-X) → Nitrile (R-C≡N) - CORRECT ANSWER-KCN
(potassium cyanide) (or NaCN) in ethanol
Nucleophilic Substitution
Haloalkane (R-X) → Amine (R-NH₂) - CORRECT ANSWER-NH₃
(ammonia) in ethanol
Carboxylic acid (R-COOH) → Ester (R-COO-R') - CORRECT
ANSWER-Alcohol (R'-OH)
concentrated H₂SO₄ catalyst
, Esterification
Primary Alcohol (R-CH₂OH) → Aldehyde (R-CHO) - CORRECT
ANSWER-Distil with K₂Cr₂O₇/H₂SO₄ (acidified potassium dichromate)
Primary Alcohol (R-CH₂OH) → Carboxylic acid (R-COOH) - CORRECT
ANSWER-Reflux with K₂Cr₂O₇/H₂SO₄ (acidified potassium
dichromate)
Uses two molecules of oxidising agent ([O]), produces one molecule of
H₂O
Secondary Alcohol (R-CH(OH)-R') → Ketone (R-C(O)-R') - CORRECT
ANSWER-Reflux with K₂Cr₂O₇/H₂SO₄ (acidified potassium
dichromate)
Byproduct: H₂O
Alkane → Haloalkane (R-X) - CORRECT ANSWER-Halogen (X₂)
Ultraviolet light (UV)
Free radical substitution