Terms in this set (89)
Unknown
RA causes
Suspected: Infection, Genetic, and Smoking
Idiopathic
OA - causes
or secondary to injury or inflammatory pathway
WAXES and WANES
morning stiffness that lasts more than 1 hour before able to move
Maliase
RA- Signs and Symptoms
usually symmetrical, starting with smaller joint of hands, feet, wrists
and then moving to bigger joints
asymmetric joint pain, insidiously: slow without s/s at 1st
follows physical activity, morning stiffness last less than 1 hour,
WORSE at the end of the day, crepitus (bone on bone), cool joints,
OA - Signs and Symptoms
limited ROM, nodes
MC in fingers, thumbs, neck, knees, hips, lower back
RA - Differentials Lupus, psoriatic arthritis, fibromyalgia
OA - Differentials joint injury, RA, gout
CBC, ESR, WBC, CMP, Rheumatoid Factor
RA - Diagnostics Synovial Fluid - cloudy and WBC
Anti-CCP
GOLD - xray - used to r/o other arthritis
shows the osteophytes and joint narrowing
OA - Diagnostics **usually diagnose based off S/S
NEGATIVE: sed rate, rheumatoid factor, ANA
, 1st line - NSAIDS or DMARDS (Celebrex)
400 mg day one, then 200mg daily after (maybe add PPI)
RA - Pharm Dose
methotrexate
7.5mg PO once a week
1st line
Celebrex
SE: increased risk for MI/Stroke, and fatal GI events
RA - Pharm SE
methotrexate
SE: elevated LFTs, nausea, infection, anemia, abdominal discomfort
!!!Can cause hepatotoxicity, monitor CBC, liver profile THIS IS
ESSENTIAL !!!!!
conservative tx first- exercise and heat
THEN:
-NSAIDS, SE: gastric ulceration, renal impairment, fluid retention **
OA - Pharm and SE
give PPI if long-term
-steroid injection, SE: wt gain, increased appetite, mood changes
rest with flare-ups
RA - nonpharm exercise when no flare-ups
- joint replacement if extensive damage
prevent further cartilage destruction - prevention is best (maintain
wt, prevent injury)
Supervised activty
OA - nonpharm
rest, braces, heat/cold, local creams
surgery
Diagnosis and Prognosis
RA - pt edu Med SE
Balance between rest and exercise
muscle strengthening
diagnosis and prognosis
med SE
OA - pt edu
*Set reasonable goals, as being pain free is not likely due to the
progressive nature of the disease but the goal is to make activities
of daily living and least amount of pain
Unknown
RA causes
Suspected: Infection, Genetic, and Smoking
Idiopathic
OA - causes
or secondary to injury or inflammatory pathway
WAXES and WANES
morning stiffness that lasts more than 1 hour before able to move
Maliase
RA- Signs and Symptoms
usually symmetrical, starting with smaller joint of hands, feet, wrists
and then moving to bigger joints
asymmetric joint pain, insidiously: slow without s/s at 1st
follows physical activity, morning stiffness last less than 1 hour,
WORSE at the end of the day, crepitus (bone on bone), cool joints,
OA - Signs and Symptoms
limited ROM, nodes
MC in fingers, thumbs, neck, knees, hips, lower back
RA - Differentials Lupus, psoriatic arthritis, fibromyalgia
OA - Differentials joint injury, RA, gout
CBC, ESR, WBC, CMP, Rheumatoid Factor
RA - Diagnostics Synovial Fluid - cloudy and WBC
Anti-CCP
GOLD - xray - used to r/o other arthritis
shows the osteophytes and joint narrowing
OA - Diagnostics **usually diagnose based off S/S
NEGATIVE: sed rate, rheumatoid factor, ANA
, 1st line - NSAIDS or DMARDS (Celebrex)
400 mg day one, then 200mg daily after (maybe add PPI)
RA - Pharm Dose
methotrexate
7.5mg PO once a week
1st line
Celebrex
SE: increased risk for MI/Stroke, and fatal GI events
RA - Pharm SE
methotrexate
SE: elevated LFTs, nausea, infection, anemia, abdominal discomfort
!!!Can cause hepatotoxicity, monitor CBC, liver profile THIS IS
ESSENTIAL !!!!!
conservative tx first- exercise and heat
THEN:
-NSAIDS, SE: gastric ulceration, renal impairment, fluid retention **
OA - Pharm and SE
give PPI if long-term
-steroid injection, SE: wt gain, increased appetite, mood changes
rest with flare-ups
RA - nonpharm exercise when no flare-ups
- joint replacement if extensive damage
prevent further cartilage destruction - prevention is best (maintain
wt, prevent injury)
Supervised activty
OA - nonpharm
rest, braces, heat/cold, local creams
surgery
Diagnosis and Prognosis
RA - pt edu Med SE
Balance between rest and exercise
muscle strengthening
diagnosis and prognosis
med SE
OA - pt edu
*Set reasonable goals, as being pain free is not likely due to the
progressive nature of the disease but the goal is to make activities
of daily living and least amount of pain
