UPDATE!!!!!2025/2026|GUARANTEED
Extravasation - ANSWER leak of drug capable of causing tissue damage from the vessel
in which it is administered into surrounding tissue/unintended sites
Irritant - ANSWER can cause inflammation, pain, burning, but rarely cause tissue
necrosis
Vesicant - ANSWER can cause blistering and significant pain, tissue damage and
destruction, leading to tissue death
antineoplastics classification for potential to cause damage - ANSWER 1. irritant
2. non-irritant
3. vesicant
4. non-vesicant
Non-DNA binding agent - ANSWER solutions remain in local area of extravasation
(improves possibility of drug deactivation)
DNA Binding Agent - ANSWER attach to DNA nucleic acid and cause antagonist to be
ingested cellularly leading to progressive tissue destruction
1
Extravasation - ANSWER leak of drug capable of causing tissue damage from the vessel
in which it is administered into surrounding tissue/unintended sites
Irritant - ANSWER can cause inflammation, pain, burning, but rarely cause tissue
necrosis
Vesicant - ANSWER can cause blistering and significant pain, tissue damage and
destruction, leading to tissue death
antineoplastics classification for potential to cause damage - ANSWER 1. irritant
2. non-irritant
3. vesicant
4. non-vesicant
Non-DNA binding agent - ANSWER solutions remain in local area of extravasation
(improves possibility of drug deactivation)
DNA Binding Agent - ANSWER attach to DNA nucleic acid and cause antagonist to be
ingested cellularly leading to progressive tissue destruction
1
