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TEST BANK FOR : Understanding Pathophysiology Verified Questions and Answers with Rationales Graded A+ Guaranteed Pass

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TEST BANK FOR : Understanding Pathophysiology Verified Questions and Answers with Rationales Graded A+ Guaranteed Pass PART ONE BASIC CONCEPTS OF PATHOPHYSIOLOGY Unit 1 The Cell 1. Cellular Biology, 1 2. Genes and Genetic Diseases, 5 3. Altered Cellular and Tissue Biology, 11 4. Fluids and Electrolytes, Acids and Bases, 17 Unit 2 Mechanisms of Self-Defense 5. Innate Immunity: Inflammation and Wound Healing, 25 6. Third Line of Defense: Adaptive Immunity, 33 7. Infection and Defects in Mechanisms of Defense, 39 8. Stress and Disease, 47 Unit 3 Cellular Proliferation: Cancer 9. Biology, Clinical Manifestations, and Treatment of Cancer, 53 10. Cancer Epidemiology, 63 Contents 11. Cancer in Children, 69 PART TWO BODY SYSTEMS AND DISEASES Unit 4 The Neurologic System 12. Structure and Function of the Neurologic System, 73 13. Pain, Temperature, Sleep, and Sensory Function, 77 14. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function, 85 15. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction, 95 16. Alterations of Neurologic Function in Children, 107 Unit 5 The Endocrine System 17. Mechanisms of Hormonal Regulation, 113 18. Alterations of Hormonal Regulation, 117 Unit 6 The Hematologic System 19. Structure and Function of the Hematologic System, 131 20. Alterations of Hematologic Function, 135 21. Alterations of Hematologic Function in Children, 147 Unit 7 The Cardiovascular and Lymphatic Systems 22. Structure and Function of the Cardiovascular and Lymphatic Systems, 153 23. Alterations of Cardiovascular Function, 157 24. Alterations of Cardiovascular Function in Children, 177 Unit 8 The Pulmonary System 25. Structure and Function of the Pulmonary System, 183 26. Alterations of Pulmonary Function, 187 27. Alterations of Pulmonary Function in Children, 199 Unit 9 The Renal and Urologic Systems 28. Structure and Function of the Renal and Urologic Systems, 205 29. Alterations of Renal and Urinary Tract Function, 209 30. Alterations of Renal and Urinary Tract Function in Children, 219 Unit 10 The Reproductive Systems 31. Structure and Function of the Reproductive Systems, 225 32. Alterations of the Reproductive Systems, Including Sexually Transmitted Infections, 229 Unit 11 The Digestive System 33. Structure and Function of the Digestive System, 243 34. Alterations of Digestive Function, 247 35. Alterations of Digestive Function in Children, 261 Unit 12 The Musculoskeletal and Integumentary Systems 36. Structure and Function of the Musculoskeletal System, 267 37. Alterations of Musculoskeletal Function, 271 38. Alterations of Musculoskeletal Function in Children, 285 39. Structure, Function, and Disorders of the Integument, 291 40. Alterations of the Integument in Children, 303 Answers to Practice Examinations, 309 This page was intentionally left blank 1 Chapter 1 Cellular Biology

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Understanding Pathophysiology
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November 20, 2025
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,Chapter01: Cellular Biology g g
g g
g




Huether andMcCance: Understanding
gg g g g




Pathophysiology,5thEdition
gg g




Chapter 01: Cellular gg gg



BiologyTest Bank
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MULTIPLECHOICE
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1. A student is observing a cell under the microscope. It is observed to have
gg gg gg gg gg gg gg gg gg gg gg gg gg



supercoiled DNA with histones. Which of the following would also be observed
gg gg gg gg gg gg gg gg gg gg gg gg



bythe student?
gg gg



a. A single circular chromosome gg gg gg




b. A nucleus gg




c. Free-floating nuclear material gg gg




d. No organelles g




ANS: B
gg gg




The cell described is a eukaryotic cell, so it has histones and a supercoiled
gg gg gg gg gg gg gg gg gg gg gg gg gg



DNAwithin its nucleus; thus, the nucleus should be observed.
l gg gg gg gg gg gg gg gg



A single circular chromosome is characteristic of prokaryotic cells, which do not
gg gg gg gg gg gg gg gg gg gg gg



havehistones.
gg



Free-floating nuclear material describes a prokaryotic cell, which would not have
gg gg gg gg gg gg gg gg gg gg



adistinct nucleus.
gg l gg



Eukaryotic cells have membrane bounded cellular components called organelles.
gg gg gg gg gg gg gg gg



Noorganelles describes aprokaryotic cell.
gg gg gg gg



REF: p. 2 gg g



2. A nurse is instructing the staff about cellular functions. Which cellular
gg gg gg gg gg gg gg gg gg gg



function is the nurse describing when an isolated cell absorbs oxygen and uses it
gg gg l gg gg gg gg gg gg gg gg gg gg gg



to transform nutrients to energy?
gg gg gg gg gg



a. Metabolicabsorption
b. Communication
c. Secretion
d. Respiration
ANS: D
gg gg



The ability of the cell to absorb oxygen refers to the cell’s function of respiration.
gg gg gg gg gg gg gg gg gg gg gg gg gg gg

,The ability of the cell to function within a society of cells refers to its function
gg gg gg gg gg gg gg gg gg gg gg gg gg gg gg



ofcommunication.
gg l




The ability of the cell to take in nutrients refers to the cell’s function of
gg gg gg gg gg gg gg gg gg gg gg gg gg gg



metabolicabsorption.
gg l




The ability of the cell to synthesize new substances and secrete these elsewhere refersto
gg gg gg gg gg gg gg gg gg gg gg gg gg l




the cell’s function of secretion.
gg gg gg gg gg



REF: p. 3 gg g



3. A eukaryotic cell is undergoing DNA replication. In which region of the cell
gg gg gg gg gg gg gg gg gg gg gg gg



wouldmost of the genetic information be contained?
gg gg gg gg gg gg gg



a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS: C
gg gg




The region of the cell that contains genetic material, including a large amount
gg gg gg gg gg gg gg gg gg gg gg gg



of ribonucleic acid, most of the DNA, and DNA-binding
gg g g g g g g g g g g g g g g



g proteins, is the nucleolus.The mitochondria is the site of cellular respiration.
g g g g g gg gg gg gg gg gg gg gg



Theribosomes are involved in manufacturing ofproteinswithin thecell.
gg gg gg gg gg gg



The nucleus contains the nucleolus, and it is the nucleolus
g g g g g g g g g g g g g g g g g g



g gthat contains geneticmaterial.
g g gg l




REF: p. 5 gg g



4. The fluid mosaic model for biologic membranes describes membrane behavior.
gg gg gg gg gg gg gg gg gg



According to this model, which of the following float singly or as aggregates
gg gg gg gg gg gg gg gg gg gg gg gg gg



in thefluid lipid bilayer?
gg gg gg gg



a. Peripheral membraneproteins gg




b. Integralmembraneproteins
c. Glycoproteins
d. Celladhesion molecules gg




ANS: B
gg gg




Integralmembraneproteins float freely in the fluid lipid bilayer. gg g gg gg gg gg gg



Peripheral membrane proteins are not embedded in the layer, but reside at the
gg gg gg gg gg gg gg gg gg gg gg gg



surface.Glycoproteins act as cell surface markers.
gg gg gg gg gg gg

, Cell adhesion molecules are on the outside of the membrane and allow cells to
gg gg gg gg gg gg gg gg gg gg gg gg gg



hooktogether.
gg l




REF: p. 6 gg g



5. Which of the following can bind to plasma membrane receptors?
gg gg gg gg gg gg gg gg gg



a. Oxygen
b. Ribosomes
c. Amphipathic lipids gg




d. Ligands
ANS: D
gg gg




Ligands are specific molecules that can bind with receptors on the cell
gg gg gg gg gg gg gg gg gg gg gg



membrane.Oxygen moves by diffusion; it does notbind to receptors. gg gg gg gg gg g gg gg



Ribosomes make proteins and are not involved in
gg gg gg gg gg gg gg gg



binding.Amphipathic lipids are a portion of the cell
gg gg gg gg gg gg gg gg



membrane.
REF: p. 11gg gg



6. A nurse is reviewing a report from a patient with metastatic cancer. What finding
gg gg gg gg gg gg gg gg gg gg gg gg gg



would support the diagnosis of metastatic cancer? Alterations in extracellular
gg gg gg gg gg gg gg gg gg gg



matrix that include:
gg l g



a. Decreased fibronectin gg




b. Increased collagen gg




c. Decreased elastin gg




d. Increasedglycoproteins
ANS: A
gg gg




Reduced amounts of fibronectin are found in some types of cancerous cells,
gg gg gg gg gg gg gg gg gg gg gg



allowingcancer cells to travel, or metastasize.
l gg gg gg gg gg



Collagen provides strength, and its breakdown is associated with osteoarthritis,
gg gg gg gg gg gg gg gg gg



notcancer.
gg l




Elastin is found in the lungs and allows tissues to stretch; it is not associated
gg gg gg gg gg gg gg gg gg gg gg gg gg gg



withcancerous cells.
gg l gg



Decreased, not increased, glycoproteins are associated with cancerous
gg gg gg gg gg gg gg



cells.REF: p. 8
gg gg gg



7. Which form of cell communication is used to relate to other cells in direct
gg gg gg gg gg gg gg gg gg gg gg gg gg



physicalcontact?
gg

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