ONS Chemotherapy
Immunotherapy Certificate Exam
Questions and Answers
1. What are the three major phases of cell division?
Interphase
Mitotic phase
Cytokinesis
2. What are the three steps of interphase?
First growth phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
3. What are the four phases of mitosis?
Prophase
Metaphase
, Anaphase
Telophase
4. Innate immunity is characterized by:
Non-specific response, including:
1. Barrier defenses (skin, mucous membranes, flora of skin/gut)
2. Cellular components (phagocytes, natural killer cells,
granulocytes, macrophages)
5. Adaptive immunity follows innate immunity if unsuccessful and
includes:
Memory immunity, including:
1. Humoral immunity (antibody or immunoglobulin production)
2. Cell-mediated immunity (T-cell dependent)
3. Regulatory T cells (prevent autoimmune reactions and limit
inflammation)
6. What are mutations?
Variations in the nucleotide sequence of a gene.
,7. What are the three main goals of cancer treatment?
Cure
Control
Palliation
8. What is neoadjuvant therapy?
Treatment given prior to surgery to shrink the tumor.
9. What is adjuvant therapy?
Additional cancer treatment given after primary therapy to
reduce recurrence risk.
10. What is conditioning/preparative therapy?
Treatments used to prepare a patient for stem cell
transplantation.
11. What are the two types of conditioning therapies?
Myeloablative
, Nonmyeloablative
12. How is dose density defined?
Drug dose per unit time.
13. How is dose intensity defined?
Amount of drug delivered over a specified period of time.
14. How is relative dose intensity (RDI) calculated?
By comparing the actual dose received to the planned dose of
the standard regimen.
15. How do alkylating agents work?
They cause breaks in the DNA helix, interfering with replication
and leading to cell death.
16. What are the three subcategories of alkylating agents?
1. Nitrogen mustards
Immunotherapy Certificate Exam
Questions and Answers
1. What are the three major phases of cell division?
Interphase
Mitotic phase
Cytokinesis
2. What are the three steps of interphase?
First growth phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
3. What are the four phases of mitosis?
Prophase
Metaphase
, Anaphase
Telophase
4. Innate immunity is characterized by:
Non-specific response, including:
1. Barrier defenses (skin, mucous membranes, flora of skin/gut)
2. Cellular components (phagocytes, natural killer cells,
granulocytes, macrophages)
5. Adaptive immunity follows innate immunity if unsuccessful and
includes:
Memory immunity, including:
1. Humoral immunity (antibody or immunoglobulin production)
2. Cell-mediated immunity (T-cell dependent)
3. Regulatory T cells (prevent autoimmune reactions and limit
inflammation)
6. What are mutations?
Variations in the nucleotide sequence of a gene.
,7. What are the three main goals of cancer treatment?
Cure
Control
Palliation
8. What is neoadjuvant therapy?
Treatment given prior to surgery to shrink the tumor.
9. What is adjuvant therapy?
Additional cancer treatment given after primary therapy to
reduce recurrence risk.
10. What is conditioning/preparative therapy?
Treatments used to prepare a patient for stem cell
transplantation.
11. What are the two types of conditioning therapies?
Myeloablative
, Nonmyeloablative
12. How is dose density defined?
Drug dose per unit time.
13. How is dose intensity defined?
Amount of drug delivered over a specified period of time.
14. How is relative dose intensity (RDI) calculated?
By comparing the actual dose received to the planned dose of
the standard regimen.
15. How do alkylating agents work?
They cause breaks in the DNA helix, interfering with replication
and leading to cell death.
16. What are the three subcategories of alkylating agents?
1. Nitrogen mustards
