Pharmacology Exam 3 Drug List
EXAM QUESTIONS WITH CORRECT
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What is the MOA of lomustine? - ANSWER ✓ Cross links DNA
What is the cell cycle specificity of lomustine? - ANSWER ✓ Not cell cycle
specific
What are the uses of lomustine? - ANSWER ✓ Alkylating agent; first-pass
metabolism
What are the adverse effects of lomustine? - ANSWER ✓ Myelosuppression,
hepatotoxicity, neutropenia
What is the MOA of procarbazine? - ANSWER ✓ Cross links DNA
What is the cell cycle specificity of procarbazine? - ANSWER ✓ Not cell cycle
specific
What are the uses of procarbazine? - ANSWER ✓ Alkylating agent
What are the adverse effects of procarbazine? - ANSWER ✓ None listed
What is the MOA of cisplatin? - ANSWER ✓ Cross links DNA (platinum
derived)
What is the cell cycle specificity of cisplatin? - ANSWER ✓ Not cell cycle
specific
,What are the uses of cisplatin? - ANSWER ✓ Alkylating agent
What are the adverse effects of cisplatin? - ANSWER ✓ Fatal pulmonary edema
in cats, nephrotoxicity, nausea
What is the MOA of carboplatin? - ANSWER ✓ Cross links DNA (platinum
derived)
What is the cell cycle specificity of carboplatin? - ANSWER ✓ Not cell cycle
specific
What are the uses of carboplatin? - ANSWER ✓ Alkylating agent; safer platinum
compound for cats
What are the adverse effects of carboplatin? - ANSWER ✓ Myelosuppression,
monitor platelets, GI effects
What is the MOA of methotrexate? - ANSWER ✓ Inhibits pyrimidine and purine
synthesis, disrupts DNA
What is the cell cycle specificity of methotrexate? - ANSWER ✓ S phase arrest
What are the uses of methotrexate? - ANSWER ✓ Antimetabolite
What are the adverse effects of methotrexate? - ANSWER ✓ Myelosuppression,
GI effects
What is the MOA of 5-fluorouracil? - ANSWER ✓ Pyrimidine analog, disrupts
DNA
What is the cell cycle specificity of 5-fluorouracil? - ANSWER ✓ S phase arrest
What are the uses of 5-fluorouracil? - ANSWER ✓ Antimetabolite
What are the adverse effects of 5-fluorouracil? - ANSWER ✓ Contraindicated in
cats with seizures
, What is the MOA of cytosine arabinoside (cytarabine)? - ANSWER ✓ Pyrimidine
analog, disrupts DNA
What is the cell cycle specificity of cytosine arabinoside? - ANSWER ✓ S phase
arrest
What are the uses of cytosine arabinoside? - ANSWER ✓ Antimetabolite; crosses
the blood-brain barrier
What are the adverse effects of cytosine arabinoside? - ANSWER ✓ None listed
What is the MOA of doxorubicin? - ANSWER ✓ Inhibits topoisomerase II
What is the cell cycle specificity of doxorubicin? - ANSWER ✓ Not cell cycle
specific
What are the uses of doxorubicin? - ANSWER ✓ Antibiotic
What are the adverse effects of doxorubicin? - ANSWER ✓ Cardiotoxicity,
anaphylaxis, vesicant
What is the MOA of mitoxantrone? - ANSWER ✓ Inhibits topoisomerase II
What is the cell cycle specificity of mitoxantrone? - ANSWER ✓ Not cell cycle
specific
What are the uses of mitoxantrone? - ANSWER ✓ Antibiotic; non-cardiotoxic
substitute for doxorubicin
What are the adverse effects of mitoxantrone? - ANSWER ✓ Myelosuppression,
GI effects
What is the MOA of actinomycin D? - ANSWER ✓ Inhibits topoisomerase II
What is the cell cycle specificity of actinomycin D? - ANSWER ✓ Not cell cycle
specific
EXAM QUESTIONS WITH CORRECT
SOLUTIONS||100% GUARANTEED
PASS||UPDATED
2025/2026||ALREADY
GRADED!!||<<NEWEST VERSION>>
What is the MOA of lomustine? - ANSWER ✓ Cross links DNA
What is the cell cycle specificity of lomustine? - ANSWER ✓ Not cell cycle
specific
What are the uses of lomustine? - ANSWER ✓ Alkylating agent; first-pass
metabolism
What are the adverse effects of lomustine? - ANSWER ✓ Myelosuppression,
hepatotoxicity, neutropenia
What is the MOA of procarbazine? - ANSWER ✓ Cross links DNA
What is the cell cycle specificity of procarbazine? - ANSWER ✓ Not cell cycle
specific
What are the uses of procarbazine? - ANSWER ✓ Alkylating agent
What are the adverse effects of procarbazine? - ANSWER ✓ None listed
What is the MOA of cisplatin? - ANSWER ✓ Cross links DNA (platinum
derived)
What is the cell cycle specificity of cisplatin? - ANSWER ✓ Not cell cycle
specific
,What are the uses of cisplatin? - ANSWER ✓ Alkylating agent
What are the adverse effects of cisplatin? - ANSWER ✓ Fatal pulmonary edema
in cats, nephrotoxicity, nausea
What is the MOA of carboplatin? - ANSWER ✓ Cross links DNA (platinum
derived)
What is the cell cycle specificity of carboplatin? - ANSWER ✓ Not cell cycle
specific
What are the uses of carboplatin? - ANSWER ✓ Alkylating agent; safer platinum
compound for cats
What are the adverse effects of carboplatin? - ANSWER ✓ Myelosuppression,
monitor platelets, GI effects
What is the MOA of methotrexate? - ANSWER ✓ Inhibits pyrimidine and purine
synthesis, disrupts DNA
What is the cell cycle specificity of methotrexate? - ANSWER ✓ S phase arrest
What are the uses of methotrexate? - ANSWER ✓ Antimetabolite
What are the adverse effects of methotrexate? - ANSWER ✓ Myelosuppression,
GI effects
What is the MOA of 5-fluorouracil? - ANSWER ✓ Pyrimidine analog, disrupts
DNA
What is the cell cycle specificity of 5-fluorouracil? - ANSWER ✓ S phase arrest
What are the uses of 5-fluorouracil? - ANSWER ✓ Antimetabolite
What are the adverse effects of 5-fluorouracil? - ANSWER ✓ Contraindicated in
cats with seizures
, What is the MOA of cytosine arabinoside (cytarabine)? - ANSWER ✓ Pyrimidine
analog, disrupts DNA
What is the cell cycle specificity of cytosine arabinoside? - ANSWER ✓ S phase
arrest
What are the uses of cytosine arabinoside? - ANSWER ✓ Antimetabolite; crosses
the blood-brain barrier
What are the adverse effects of cytosine arabinoside? - ANSWER ✓ None listed
What is the MOA of doxorubicin? - ANSWER ✓ Inhibits topoisomerase II
What is the cell cycle specificity of doxorubicin? - ANSWER ✓ Not cell cycle
specific
What are the uses of doxorubicin? - ANSWER ✓ Antibiotic
What are the adverse effects of doxorubicin? - ANSWER ✓ Cardiotoxicity,
anaphylaxis, vesicant
What is the MOA of mitoxantrone? - ANSWER ✓ Inhibits topoisomerase II
What is the cell cycle specificity of mitoxantrone? - ANSWER ✓ Not cell cycle
specific
What are the uses of mitoxantrone? - ANSWER ✓ Antibiotic; non-cardiotoxic
substitute for doxorubicin
What are the adverse effects of mitoxantrone? - ANSWER ✓ Myelosuppression,
GI effects
What is the MOA of actinomycin D? - ANSWER ✓ Inhibits topoisomerase II
What is the cell cycle specificity of actinomycin D? - ANSWER ✓ Not cell cycle
specific
