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NBME CBSE BIOCHEMISTRY LIPIDS TEST
EXAM VERIFIED QUESTIONS & 100%
ACCURATE ANSWERS | COMPLETELY
UPDATED 2025–2026 EDITION A+
PERFORMANCE GUARANTEED
What enzyme allows for cholesterol synthesis in the liver?
HMG-CoA reductase
What enzyme esterifies cholesterol in HDL and packs esters densely in the core?
Lecithin-cholesterol acyl transferase (LCAT)
What receptor does LDL recognize?
B-100
What apo-B protein is present on cyclomicrons?
B-48
What receptor do lipoprotein lipase recognize?
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C-II
What enzyme in HDL removes triglycerides from VLDL?
Cholesteryl ester transfer protein (CETP)
What protein do liver receptors recognize for uptake of HDL,VLDL,
cyclomicrons?
Apo CII
What lipoprotein is highest in cholesterol?
LDL
An infant presents to the hospital with steatorrhea, abdominal distension, and
failure to thrive. Upon further evaluation, there are vitamin deficiencies especially
E causing ataxia and weakness. There is also lipid accumulation in enterocytes.
What is the presumed prognosis?
Abetalipoproteinemia
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An infant presents to the hospital and lab work is conducted. There is low or zero
VLDL,IDL,LDL and very low triglyceride and total cholesterol levels.
additionally, there is acanthocytosis (abnormal RBC membranes). What is the
presumed prognosis?
Abetalipoproteinemia
What enzyme is deficient in Abetalipoproteinemia?
microsomal triglyceride transfer protein (MTP)
A child/adult presents to the hospital with xanthomas, tendinous xanthoma
specifically in the Achilles and corneal arcus. What is the presumed prognosis?
hyperlipidemia
An individual presents to the hospital with an autosomal recessive defect. Lab
findings show >1000 triglycerides and elevated chylomicrons. They have reccurent
pancreatitis, enlarged liver, xanthomas, and are being treated with a very low fat
diet. What is the presumed prognosis?
Familial Dyslipidemia (Type I Hyperchylomicronemia)
NBME CBSE BIOCHEMISTRY LIPIDS TEST
EXAM VERIFIED QUESTIONS & 100%
ACCURATE ANSWERS | COMPLETELY
UPDATED 2025–2026 EDITION A+
PERFORMANCE GUARANTEED
What enzyme allows for cholesterol synthesis in the liver?
HMG-CoA reductase
What enzyme esterifies cholesterol in HDL and packs esters densely in the core?
Lecithin-cholesterol acyl transferase (LCAT)
What receptor does LDL recognize?
B-100
What apo-B protein is present on cyclomicrons?
B-48
What receptor do lipoprotein lipase recognize?
,2|Page
C-II
What enzyme in HDL removes triglycerides from VLDL?
Cholesteryl ester transfer protein (CETP)
What protein do liver receptors recognize for uptake of HDL,VLDL,
cyclomicrons?
Apo CII
What lipoprotein is highest in cholesterol?
LDL
An infant presents to the hospital with steatorrhea, abdominal distension, and
failure to thrive. Upon further evaluation, there are vitamin deficiencies especially
E causing ataxia and weakness. There is also lipid accumulation in enterocytes.
What is the presumed prognosis?
Abetalipoproteinemia
, 3|Page
An infant presents to the hospital and lab work is conducted. There is low or zero
VLDL,IDL,LDL and very low triglyceride and total cholesterol levels.
additionally, there is acanthocytosis (abnormal RBC membranes). What is the
presumed prognosis?
Abetalipoproteinemia
What enzyme is deficient in Abetalipoproteinemia?
microsomal triglyceride transfer protein (MTP)
A child/adult presents to the hospital with xanthomas, tendinous xanthoma
specifically in the Achilles and corneal arcus. What is the presumed prognosis?
hyperlipidemia
An individual presents to the hospital with an autosomal recessive defect. Lab
findings show >1000 triglycerides and elevated chylomicrons. They have reccurent
pancreatitis, enlarged liver, xanthomas, and are being treated with a very low fat
diet. What is the presumed prognosis?
Familial Dyslipidemia (Type I Hyperchylomicronemia)
