complete solution
SSRI MOA
block the reuptake of serotonin at the presynaptic neuron
What is the first line treatment for depression
SSRIs (selective serotonin reuptake inhibitors)
Biggest SEs from SSRI
- Weight gain (d/t retained fluid)
- Sexual dysfunction
- Potential for serotonin syndrome if combined with other meds like MAOIs/TCAs
What symptoms can occur after discontinuing SSRIs
Withdrawal sx: headache, dizziness, weakness, nausea, insomnia
6wks after d/c
Serotonin syndrome stages
1) diarrhea
2) restlessness