NAPLEX diabetes 2025/2026
Complete Questions And Correct
Answers (Verified Answers)|Brand
New Version Grade A+!
test used to identify patients who still produce insulin Correct Answer: C peptide
examples of macrovascular disease Correct Answer: coronary artery disease,
cerebrovascular disease, peripheral artery disease
which group has a higher risk of DM with a lower BMI Correct Answer: Asian
Americans
Pre diabetes dx criteria Correct Answer: fasting glucose 100-125; 2 hr plasma
glucose (75g) 140-199; or A1c 5.7-6.4%
Diabetes criteria for diagnosis Correct Answer: symptoms plus random glucose >
200; fasting > 126; 2 hour OGTT > 200 or A1c > 6.5%
meds that can increase blood glucose Correct Answer: atypical antipsych,
azoles (posa), beta agonists, BB (carvedilol, propranolol), cough syrup,
cyclosporine, FK, sirolimus, Diazoxide, interferon alfa, niacin, octreotide,
protease inhib, quinolones, steroids, thiazides, loops
drugs that lower blood glucose Correct Answer: linezolid, lorcaserin (Belviq),
Octreotide (with Type 1), pentamidine, propranolol and non-selective BB,
Quinine, quinolones
Gestational diabetes goals Correct Answer: preprandial < 95; 1 hour post < 140,
2 hours post < 120
,Pregestational diabetes goals Correct Answer: A1c < 6%, preprandial 60-99,
peak post-prandial 100-129
goal waist circumference Correct Answer: < 35 inches female; < 40 inches male
goal fiber intake Correct Answer: 14 grams per 1,000 kcal; 25 g for females and
38 g for males
who should get aspirin therapy as primary prevention Correct Answer: males >
50 and females > 60 with at least 1 additional factor (HTN, CVD, family hx,
smoking, etc)
what should be used if patient has aspirin allergy Correct Answer: clopidogrel
75mg
benefit of ACEI and ARBs Correct Answer: delay progression to diabetic
nephropathy in those with albuminuria
when do patients qualify for high intensity statin Correct Answer: <40 years with
overt CVD or >40 year with CVD risk factors or overt CVD
vaccinations indicated for diabetic patients Correct Answer: Hep B if
unvaccinated between 19-59; influenza, pneumococcal; Tetanus if due
ADA guidelines Correct Answer: < 7%, preprandial 80-130; peak post-prandial <
180
AACE guidelines Correct Answer: < 6.5%, preprandial < 110, peak post-prandial
< 140
when should initial therapy contain two drugs Correct Answer: A1c >/= 9
when should initial therapy include insulin Correct Answer: A1c > 10 or BG > 300
, at one point should an additional agent be added Correct Answer: A1c not at
goal after 3 months
which three drug regimens are not recommended Correct Answer: metformin +
DPP4 + GLP1 or metformin + SGLT2 + GLP1
medications with only moderate efficacy Correct Answer: DPP4 inhib, SGLT2
inhib, pramlintide
moderate risk of hypoglycemia Correct Answer: SU adn meglitinides
drugs that can cause weight loss Correct Answer: GLP1 agonists, SGLT2 inhib,
primlintide
drugs that cause weight gain Correct Answer: insulin, SUs, meglitinides, TZDs
which medications increase insulin secretion Correct Answer: SUs and
Meglitinides
how does metformin work Correct Answer: decreases hepatic glucose
production, decreases glucose absorption, and increases sensitivity
when is metformin CI Correct Answer: Scr > 1.5 in males, > 1.4 in females
Metaglip Correct Answer: metformin and glipizide
Glucovance Correct Answer: metformin and glyburide
Actoplus Met Correct Answer: pioglitazone and metformin
Avandamet Correct Answer: rosiglitazone and metformin
Janumet Correct Answer: sitagliptin and metformin
Complete Questions And Correct
Answers (Verified Answers)|Brand
New Version Grade A+!
test used to identify patients who still produce insulin Correct Answer: C peptide
examples of macrovascular disease Correct Answer: coronary artery disease,
cerebrovascular disease, peripheral artery disease
which group has a higher risk of DM with a lower BMI Correct Answer: Asian
Americans
Pre diabetes dx criteria Correct Answer: fasting glucose 100-125; 2 hr plasma
glucose (75g) 140-199; or A1c 5.7-6.4%
Diabetes criteria for diagnosis Correct Answer: symptoms plus random glucose >
200; fasting > 126; 2 hour OGTT > 200 or A1c > 6.5%
meds that can increase blood glucose Correct Answer: atypical antipsych,
azoles (posa), beta agonists, BB (carvedilol, propranolol), cough syrup,
cyclosporine, FK, sirolimus, Diazoxide, interferon alfa, niacin, octreotide,
protease inhib, quinolones, steroids, thiazides, loops
drugs that lower blood glucose Correct Answer: linezolid, lorcaserin (Belviq),
Octreotide (with Type 1), pentamidine, propranolol and non-selective BB,
Quinine, quinolones
Gestational diabetes goals Correct Answer: preprandial < 95; 1 hour post < 140,
2 hours post < 120
,Pregestational diabetes goals Correct Answer: A1c < 6%, preprandial 60-99,
peak post-prandial 100-129
goal waist circumference Correct Answer: < 35 inches female; < 40 inches male
goal fiber intake Correct Answer: 14 grams per 1,000 kcal; 25 g for females and
38 g for males
who should get aspirin therapy as primary prevention Correct Answer: males >
50 and females > 60 with at least 1 additional factor (HTN, CVD, family hx,
smoking, etc)
what should be used if patient has aspirin allergy Correct Answer: clopidogrel
75mg
benefit of ACEI and ARBs Correct Answer: delay progression to diabetic
nephropathy in those with albuminuria
when do patients qualify for high intensity statin Correct Answer: <40 years with
overt CVD or >40 year with CVD risk factors or overt CVD
vaccinations indicated for diabetic patients Correct Answer: Hep B if
unvaccinated between 19-59; influenza, pneumococcal; Tetanus if due
ADA guidelines Correct Answer: < 7%, preprandial 80-130; peak post-prandial <
180
AACE guidelines Correct Answer: < 6.5%, preprandial < 110, peak post-prandial
< 140
when should initial therapy contain two drugs Correct Answer: A1c >/= 9
when should initial therapy include insulin Correct Answer: A1c > 10 or BG > 300
, at one point should an additional agent be added Correct Answer: A1c not at
goal after 3 months
which three drug regimens are not recommended Correct Answer: metformin +
DPP4 + GLP1 or metformin + SGLT2 + GLP1
medications with only moderate efficacy Correct Answer: DPP4 inhib, SGLT2
inhib, pramlintide
moderate risk of hypoglycemia Correct Answer: SU adn meglitinides
drugs that can cause weight loss Correct Answer: GLP1 agonists, SGLT2 inhib,
primlintide
drugs that cause weight gain Correct Answer: insulin, SUs, meglitinides, TZDs
which medications increase insulin secretion Correct Answer: SUs and
Meglitinides
how does metformin work Correct Answer: decreases hepatic glucose
production, decreases glucose absorption, and increases sensitivity
when is metformin CI Correct Answer: Scr > 1.5 in males, > 1.4 in females
Metaglip Correct Answer: metformin and glipizide
Glucovance Correct Answer: metformin and glyburide
Actoplus Met Correct Answer: pioglitazone and metformin
Avandamet Correct Answer: rosiglitazone and metformin
Janumet Correct Answer: sitagliptin and metformin
